Novel α-KTx sites in the BK channel and comparative sequence analysis reveal distinguishing features of the BK and KV channel outer pore

Cell Biochemistry and Biophysics

Volumn 52, Issue 1, 2008, Pages 47-58

  Giangiacomo, Kathleen M ^a   Becker, Jennifer ^a   Garsky, Christopher ^a   Schmalhofer, William ^b   Garcia, Maria L ^b   Mullmann, Theodore J ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

KTx; BK; Iberiotoxin; Kcsa; KV1; MthK; Slo1; Slo2; Slo3

Indexed keywords

ANIMALIA;

LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; PEPTIDE; POTASSIUM CHANNEL BLOCKING AGENT; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CHANNEL GATING; CHEMICAL STRUCTURE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; RAT; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; HUMANS; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STRUCTURE, SECONDARY; RATS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS;

EID: 58149241373     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-008-9026-3     Document Type: Article

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