Revealing the molecular determinants of neurotoxin specificity for calcium-activated versus voltage-dependent potassium channels

Biochemistry

Volumn 46, Issue 18, 2007, Pages 5358-5364

  Giangiacomo, Kathleen M ^a   Becker, Jennifer ^a   Garsky, Christopher ^a   Felix, John P ^b   Priest, Birgit T ^b   Schmalhofer, William ^b   Garcia, Maria L ^b   Mullmann, Theodore J ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DISEASES; ELECTRIC POTENTIAL; FREE ENERGY; MOLECULAR STRUCTURE; POTASSIUM;

BINDING FREE ENERGY; MOLECULAR DETERMINANTS; POTASSIUM CHANNELS;

NEUROLOGY;

CALCIUM ACTIVATED POTASSIUM CHANNEL; NEUROTOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; VOLTAGE GATED POTASSIUM CHANNEL;

ACCURACY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CHARYBDOTOXIN; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; KV1.3 POTASSIUM CHANNEL; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MOLECULAR SEQUENCE DATA; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; SCORPION VENOMS;

EID: 34248143507     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700150t     Document Type: Article

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