Physiologically based pharmacokinetic (PBPK) models for ethanol

IEEE Transactions on Biomedical Engineering

Volumn 55, Issue 12, 2008, Pages 2691-2700

  Plawecki, Martin H ^a   Han, Jae Joon ^b   Doerschuk, Peter C ^c   Ramchandani, Vijay A ^d   O'Connor, Sean J ^a,e  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Samsung Advanced Institute of Technology (SAIT)   (South Korea)

^c Cornell University   (United States)

^d NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^e PURDUE UNIVERSITY   (United States)

Author keywords

Alcohol; Ethanol; Model; Pharmacokinetics; Physiologically based pharmacokinetic (PBPK) models; Physiology

Indexed keywords

CONTROL STRATEGIES; ETHANOL CONCENTRATIONS; GOVERNING EQUATIONS; INTRAVENOUS ADMINISTRATIONS; MATHEMATICAL FOUNDATIONS; NONLINEAR ORDINARY DIFFERENTIAL EQUATIONS; PARAMETER IDENTIFICATIONS; PHARMACOKINETIC MODELS; PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELS;

ETHANOL; NONLINEAR EQUATIONS; ORDINARY DIFFERENTIAL EQUATIONS; PHARMACOKINETICS; PHYSIOLOGICAL MODELS;

MATHEMATICAL MODELS;

DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HUMANS; INFUSIONS, INTRAVENOUS; LIVER; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; NONLINEAR DYNAMICS; TISSUE DISTRIBUTION;

EID: 58149231284     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2008.919132     Document Type: Article

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