Quantitative structure-property relationships modeling of skin irritation

Toxicology in Vitro

Volumn 23, Issue 1, 2009, Pages 176-184

  Golla, Sharath ^a   Madihally, Sundar ^a   Robinson Jr , Robert L ^a   Gasem, Khaled A M ^a  

^a Oklahoma State University   (United States)

Author keywords

Draize test; Neural networks; Non linear QSPR models; Primary irritation index; Skin irritation

Indexed keywords

2 PROPANOL; ACETIC ACID; ALCOHOL; BENZALKONIUM CHLORIDE; BETAINE DERIVATIVE; DECANOIC ACID; DECANOL; DIMETHYL SULFOXIDE; GERANIOL; HEPTANOIC ACID DERIVATIVE; HEXANOL; HYDROCHLORIC ACID; LACTIC ACID; LAURIC ACID; LAURYL ALCOHOL; LINALYL ACETATE; N,N DIMETHYL N DODECYLAMINOBETAINE; OCTANOIC ACID; OCTANOL; PALMITIC ACID ISOPROPYL ESTER; POLYSORBATE 80; PROPYLENE GLYCOL; TRIETHANOLAMINE; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL NEURAL NETWORK; COMPUTER MODEL; MATHEMATICAL MODEL; MOLECULAR SIZE; PHYSICAL CHEMISTRY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SKIN IRRITATION; SKIN MANIFESTATION; SKIN PENETRATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; COMPUTER SIMULATION; DATABASES, FACTUAL; IRRITANTS; MODELS, BIOLOGICAL; NEURAL NETWORKS (COMPUTER); PREDICTIVE VALUE OF TESTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RABBITS; SKIN;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 58149179927     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.10.013     Document Type: Article

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