A robust structure-activity relationship (SAR) model for esters that cause skin irritation in humans

Toxicological Sciences

Volumn 55, Issue 1, 2000, Pages 215-222

  Smith, Jeffrey S ^a   Macina, Orest T ^a   Sussman, Nancy B ^a   Luster, Michael I ^b   Karol, Meryl H ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Computational model; Organic esters; Physicochemical parameters; Skin irritation; Structure activity relationship

Indexed keywords

BENZOIC ACID DERIVATIVE; ESTER; ORGANIC COMPOUND;

ANIMAL MODEL; ARTICLE; CONTACT DERMATITIS; DATA BASE; DERMATITIS; HUMAN; MODEL; NONHUMAN; RABBIT; SKIN IRRITATION; STATISTICAL MODEL; STRUCTURE ACTIVITY RELATION;

EID: 0034025227     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/55.1.215     Document Type: Article

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