Validity and ethics of the human 4-h patch test as an alternative method to assess acute skin irritation potential

Contact Dermatitis

Volumn 45, Issue 1, 2001, Pages 1-12

  Robinson, Michael K ^a   McFadden, John P ^b   Basketter, David A ^c  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c UNILEVER RESEARCH   (United Kingdom)

Author keywords

4 h patch test; Alternatives to animal testing; EU legistation; R38; Skin irritation

Indexed keywords

ACETIC ACID; BENZALKONIUM CHLORIDE; DECANOL; DODECYL SULFATE SODIUM; HEXANOL; IRRITANT AGENT; OCTANOL; POLYSORBATE 80; SODIUM HYDROXIDE; TRIMETHYLAMMONIUM SALT DERIVATIVE;

IN VITRO STUDY; MEDICAL ETHICS; PATCH TEST; RABBIT; REVIEW; SAFETY; SKIN IRRITATION; SKIN TEST;

BIOMEDICAL AND BEHAVIORAL RESEARCH; EMPIRICAL APPROACH;

ANIMAL TESTING ALTERNATIVES; ANIMALS; DERMATITIS, IRRITANT; ETHICS, MEDICAL; HUMANS; PATCH TESTS; RABBITS; REPRODUCIBILITY OF RESULTS; SKIN IRRITANCY TESTS;

EID: 0034946339     PISSN: 01051873     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0536.2001.045001001.x     Document Type: Review

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