In vitro skin irritation testing on reconstituted human epidermis: Reproducibility for 50 chemicals tested with two protocols

Toxicology in Vitro

Volumn 20, Issue 4, 2006, Pages 401-416

  Tornier, Carine ^a   Rosdy, Martin ^a   Maibach, Howard I ^b  

^a SkinEthic Laboratories   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alternative methods; Chemicals testing; Patch test; Skin irritation; SkinEthic; Validation

Indexed keywords

1 BROMOPENTANE; 1,1,1 TRICHLOROETHANE; 10 UNDECENOIC ACID; 2 METHYL 4 PHENYL 2 BUTANOL; 2 PROPANOL; 3 CHLORONITROBENZENE; 3,3' DITHIODIPROPIONIC ACID; 4 AMINO 1,2,4 TRIAZOLE; ALKENE DERIVATIVE; BENZENE DERIVATIVE; BUTANOL; CYCLOOCTENE; DECANOL; DIMETHYL DISULFIDE; DISULFIDE; DODECYL SULFATE SODIUM; HEXANOIC ACID DERIVATIVE; HEXANOIC ACID METHYL ESTER; HYDROXYCITRONELLAL; INTERLEUKIN 1ALPHA; LAURIC ACID METHYL ESTER; LIMONENE; OCTANOIC ACID; PALMITIC ACID ISOPROPYL ESTER; PALMITIC ACID METHYL ESTER; PENTANE; POTASSIUM HYDROXIDE; PROPIONIC ACID DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; COST; EPIDERMIS; HISTOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PATCH TEST; PHYSICAL CHEMISTRY; PROTEIN SECRETION; SKIN TEST; SKIN TOXICITY; TOXICITY TESTING;

ANIMAL TESTING ALTERNATIVES; CELL SURVIVAL; CELLS, CULTURED; EPIDERMIS; HUMANS; INTERLEUKIN-1; IRRITANTS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; TOXICITY TESTS; XENOBIOTICS;

ORYCTOLAGUS CUNICULUS;

EID: 33645220351     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.09.004     Document Type: Article

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