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Volumn 276, Issue 2, 2009, Pages 571-580

Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration

Author keywords

ATP; Gel filtration; Kinetics; Tetramerization; Thymidine kinase

Indexed keywords

PYROPHOSPHATE; THYMIDINE KINASE; THYMIDINE TRIPHOSPHATE; TRIPOLYPHOSPHATE;

EID: 58149161825     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06804.x     Document Type: Article
Times cited : (15)

References (29)
  • 1
    • 0035083865 scopus 로고    scopus 로고
    • The supply of exogenous deoxyribonucleotides accelerates the speed of the replication fork in early S-phase
    • Malinsky J, Koberna K, Stanek D, Masata M, Votruba I Raska I (2001) The supply of exogenous deoxyribonucleotides accelerates the speed of the replication fork in early S-phase. J Cell Sci 114, 747 750.
    • (2001) J Cell Sci , vol.114 , pp. 747-750
    • Malinsky, J.1    Koberna, K.2    Stanek, D.3    Masata, M.4    Votruba, I.5    Raska, I.6
  • 2
    • 33846576261 scopus 로고    scopus 로고
    • Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae
    • Chabes A Stillman B (2007) Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae. Proc Natl Acad Sci USA 104, 1183 1188.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1183-1188
    • Chabes, A.1    Stillman, B.2
  • 3
    • 0345791546 scopus 로고    scopus 로고
    • Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools
    • Koc A, Wheeler LJ, Mathews CK Merrill GF (2004) Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools. J Biol Chem 279, 223 230.
    • (2004) J Biol Chem , vol.279 , pp. 223-230
    • Koc, A.1    Wheeler, L.J.2    Mathews, C.K.3    Merrill, G.F.4
  • 4
    • 0015837824 scopus 로고
    • The deoxyribonucleoside 5′-triphosphate (dATP and dTTP) pools in phytohemagglutinin-stimulated and non-stimulated human lymphocytes
    • Munch-Petersen B, Tyrsted G Dupont B (1973) The deoxyribonucleoside 5′-triphosphate (dATP and dTTP) pools in phytohemagglutinin-stimulated and non-stimulated human lymphocytes. Exp Cell Res 79, 249 256.
    • (1973) Exp Cell Res , vol.79 , pp. 249-256
    • Munch-Petersen, B.1    Tyrsted, G.2    Dupont, B.3
  • 5
    • 0016759710 scopus 로고
    • The pool size of deoxyguanosine 5′-triphosphate and deoxycytidine 5′-triphosphate in phytohemagglutinin-stimulated and non-stimulated human lymphocytes
    • Tyrsted G (1975) The pool size of deoxyguanosine 5′-triphosphate and deoxycytidine 5′-triphosphate in phytohemagglutinin-stimulated and non-stimulated human lymphocytes. Exp Cell Res 91, 429 440.
    • (1975) Exp Cell Res , vol.91 , pp. 429-440
    • Tyrsted, G.1
  • 6
    • 0141611793 scopus 로고    scopus 로고
    • DNA building blocks at the foundation of better survival
    • Chabes A Thelander L (2003) DNA building blocks at the foundation of better survival. Cell Cycle 2, 171 173.
    • (2003) Cell Cycle , vol.2 , pp. 171-173
    • Chabes, A.1    Thelander, L.2
  • 7
    • 0023676214 scopus 로고
    • Consequences of depletion of cellular deoxyribonucleoside triphosphate pools on the excision-repair process in cultured human fibroblasts
    • Snyder RD (1988) Consequences of depletion of cellular deoxyribonucleoside triphosphate pools on the excision-repair process in cultured human fibroblasts. Mutat Res 200, 193 199.
    • (1988) Mutat Res , vol.200 , pp. 193-199
    • Snyder, R.D.1
  • 8
    • 0023925454 scopus 로고
    • Interactions between deoxyribonucleotide and DNA synthesis
    • Reichard P (1988) Interactions between deoxyribonucleotide and DNA synthesis. Annu Rev Biochem 57, 349 374.
    • (1988) Annu Rev Biochem , vol.57 , pp. 349-374
    • Reichard, P.1
  • 9
    • 33747339725 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion and thymidine phosphate pool dynamics in a cellular model of mitochondrial neurogastrointestinal encephalomyopathy
    • Pontarin G, Ferraro P, Valentino ML, Hirano M, Reichard P Bianchi V (2006) Mitochondrial DNA depletion and thymidine phosphate pool dynamics in a cellular model of mitochondrial neurogastrointestinal encephalomyopathy. J Biol Chem 281, 22720 22728.
    • (2006) J Biol Chem , vol.281 , pp. 22720-22728
    • Pontarin, G.1    Ferraro, P.2    Valentino, M.L.3    Hirano, M.4    Reichard, P.5    Bianchi, V.6
  • 11
    • 0347986676 scopus 로고    scopus 로고
    • Mitotic degradation of human thymidine kinase 1 is dependent on the anaphase-promoting complex/cyclosome-CDH1-mediated pathway
    • Ke PY Chang ZF (2004) Mitotic degradation of human thymidine kinase 1 is dependent on the anaphase-promoting complex/cyclosome-CDH1-mediated pathway. Mol Cell Biol 24, 514 526.
    • (2004) Mol Cell Biol , vol.24 , pp. 514-526
    • Ke, P.Y.1    Chang, Z.F.2
  • 12
    • 0027185675 scopus 로고
    • Reversible ATP-dependent transition between two forms of human cytosolic thymidine kinase with different enzymatic properties
    • Munch-Petersen B, Tyrsted G Cloos L (1993) Reversible ATP-dependent transition between two forms of human cytosolic thymidine kinase with different enzymatic properties. J Biol Chem 268, 15621 15625.
    • (1993) J Biol Chem , vol.268 , pp. 15621-15625
    • Munch-Petersen, B.1    Tyrsted, G.2    Cloos, L.3
  • 13
    • 0347694727 scopus 로고    scopus 로고
    • Perturbation of ATP-induced tetramerization of human cytosolic thymidine kinase by substitution of serine-13 with aspartic acid at the mitotic phosphorylation site
    • Li CL, Lu CY, Ke PY Chang ZF (2004) Perturbation of ATP-induced tetramerization of human cytosolic thymidine kinase by substitution of serine-13 with aspartic acid at the mitotic phosphorylation site. Biochem Biophys Res Commun, 313, 587 593.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 587-593
    • Li, C.L.1    Lu, C.Y.2    Ke, P.Y.3    Chang, Z.F.4
  • 15
    • 0038419639 scopus 로고    scopus 로고
    • Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
    • Sabini E, Ort S, Monnerjahn C, Konrad M Lavie A (2003) Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nat Struct Biol 10, 513 519.
    • (2003) Nat Struct Biol , vol.10 , pp. 513-519
    • Sabini, E.1    Ort, S.2    Monnerjahn, C.3    Konrad, M.4    Lavie, A.5
  • 17
    • 36749053510 scopus 로고    scopus 로고
    • Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes
    • Segura-Pena D, Lichter J, Trani M, Konrad M, Lavie A Lutz S (2007) Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes. Structure 15, 1555 1566.
    • (2007) Structure , vol.15 , pp. 1555-1566
    • Segura-Pena, D.1    Lichter, J.2    Trani, M.3    Konrad, M.4    Lavie, A.5    Lutz, S.6
  • 18
    • 0021742269 scopus 로고
    • Human thymidine kinase gene: Molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells
    • Bradshaw HD Jr. Deininger PL (1984) Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells. Mol Cell Biol 4, 2316 2320.
    • (1984) Mol Cell Biol , vol.4 , pp. 2316-2320
    • Bradshaw Jr., H.D.1    Deininger, P.L.2
  • 19
    • 0034644693 scopus 로고    scopus 로고
    • Valine, not methionine, is amino acid 106 in human cytosolic thymidine kinase (TK1). Impact on oligomerization, stability and kinetic properties
    • Berenstein D, Christensen JF, Kristensen T, Hofbauer R Munch-Petersen B (2000) Valine, not methionine, is amino acid 106 in human cytosolic thymidine kinase (TK1). Impact on oligomerization, stability and kinetic properties. J Biol Chem 275, 32187 32192.
    • (2000) J Biol Chem , vol.275 , pp. 32187-32192
    • Berenstein, D.1    Christensen, J.F.2    Kristensen, T.3    Hofbauer, R.4    Munch-Petersen, B.5
  • 20
    • 2942605819 scopus 로고    scopus 로고
    • Effect of valine 106 on structure-function relation of cytosolic human thymidine kinase. Kinetic properties and oligomerization pattern of nine substitution mutants of V106
    • Frederiksen H, Berenstein D Munch-Petersen B (2004) Effect of valine 106 on structure-function relation of cytosolic human thymidine kinase. Kinetic properties and oligomerization pattern of nine substitution mutants of V106. Eur J Biochem 271, 2248 2256.
    • (2004) Eur J Biochem , vol.271 , pp. 2248-2256
    • Frederiksen, H.1    Berenstein, D.2    Munch-Petersen, B.3
  • 22
    • 29144442291 scopus 로고    scopus 로고
    • Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme
    • Kosinska U, Carnrot C, Eriksson S, Wang L Eklund H (2005) Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme. FEBS J 272, 6365 6372.
    • (2005) FEBS J , vol.272 , pp. 6365-6372
    • Kosinska, U.1    Carnrot, C.2    Eriksson, S.3    Wang, L.4    Eklund, H.5
  • 23
    • 34247365953 scopus 로고    scopus 로고
    • Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure
    • Segura-Pena D, Lutz S, Monnerjahn C, Konrad M Lavie A (2007) Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. J Mol Biol 369, 129 141.
    • (2007) J Mol Biol , vol.369 , pp. 129-141
    • Segura-Pena, D.1    Lutz, S.2    Monnerjahn, C.3    Konrad, M.4    Lavie, A.5
  • 25
    • 0025916482 scopus 로고
    • Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides
    • Munch-Petersen B, Cloos L, Tyrsted G Eriksson S (1991) Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. J Biol Chem 266, 9032 9038.
    • (1991) J Biol Chem , vol.266 , pp. 9032-9038
    • Munch-Petersen, B.1    Cloos, L.2    Tyrsted, G.3    Eriksson, S.4
  • 26
    • 33646586729 scopus 로고    scopus 로고
    • High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics
    • Birringer MS, Perozzo R, Kut E, Stillhart C, Surber W, Scapozza L Folkers G (2006) High-level expression and purification of human thymidine kinase 1: quaternary structure, stability, and kinetics. Protein Expr Purif 47, 506 515.
    • (2006) Protein Expr Purif , vol.47 , pp. 506-515
    • Birringer, M.S.1    Perozzo, R.2    Kut, E.3    Stillhart, C.4    Surber, W.5    Scapozza, L.6    Folkers, G.7
  • 27
    • 0028489042 scopus 로고
    • International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: A critical factor in the maintenance of genetic stability
    • Kunz BA, Kohalmi SE, Kunkel TA, Mathews CK, Mcintosh EM Reidy JA (1994) International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability. Mutat Res 318, 1 64.
    • (1994) Mutat Res , vol.318 , pp. 1-64
    • Kunz, B.A.1    Kohalmi, S.E.2    Kunkel, T.A.3    Mathews, C.K.4    McIntosh, E.M.5    Reidy, J.A.6
  • 28
    • 0026352951 scopus 로고
    • Modulation of mutagenesis by deoxyribonucleotide levels
    • Kunz BA Kohalmi SE (1991) Modulation of mutagenesis by deoxyribonucleotide levels. Annu Rev Genet 25, 339 359.
    • (1991) Annu Rev Genet , vol.25 , pp. 339-359
    • Kunz, B.A.1    Kohalmi, S.E.2
  • 29
    • 23944450180 scopus 로고    scopus 로고
    • Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability
    • Ke PY, Kuo YY, Hu CM Chang ZF (2005) Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability. Genes Dev 19, 1920 1933.
    • (2005) Genes Dev , vol.19 , pp. 1920-1933
    • Ke, P.Y.1    Kuo, Y.Y.2    Hu, C.M.3    Chang, Z.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.