Effect of valine 106 on structure-function relation of cytosolic human thymidine kinase: Kinetic properties and oligomerization pattern of nine substitution mutants of V106

European Journal of Biochemistry

Volumn 271, Issue 11, 2004, Pages 2248-2256

  Frederiksen, Hanne ^a,b   Berenstein, Dvora ^a   Munch Petersen, Birgitte ^a  

^a ROSKILDE UNIVERSITY   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Dimer tetramer formation; Enzyme kinetics; Enzyme mutants; Structure function relation; Thymidine kinase

Indexed keywords

THYMIDINE KINASE; UNCLASSIFIED DRUG; VALINE; VALINE 106;

ARTICLE; CATALYSIS; CELL ACTIVITY; CONTROLLED STUDY; CYTOSOL; DNA SYNTHESIS; ENZYME ANALYSIS; ENZYME INDUCTION; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; OLIGOMERIZATION; POLARIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CYTOSOL; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE KINASE; VALINE;

EID: 2942605819     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04166.x     Document Type: Article

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