-
1
-
-
0041672570
-
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
-
Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 2003; 102: 783-788
-
(2003)
Blood
, vol.102
, pp. 783-788
-
-
Ganz, T.1
-
2
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 2004; 113: 1271-1276
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
-
3
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004; 306: 2090-2093
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
4
-
-
24744458603
-
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
-
Rivera S, Nemeth E, Gabayan V et al. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood 2005; 106: 2196-2199
-
(2005)
Blood
, vol.106
, pp. 2196-2199
-
-
Rivera, S.1
Nemeth, E.2
Gabayan, V.3
-
5
-
-
14744278436
-
Anemia of chronic disease
-
Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005; 352: 1011-1023
-
(2005)
N Engl J Med
, vol.352
, pp. 1011-1023
-
-
Weiss, G.1
Goodnough, L.T.2
-
7
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
Babitt JL, Huang FW, Wrighting DM et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 2006; 38: 531-539
-
(2006)
Nat Genet
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
Huang, F.W.2
Wrighting, D.M.3
-
8
-
-
34447137331
-
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
-
Babitt JL, Huang FW, Xia Y et al.Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest 2007; 117: 1933-1939
-
(2007)
J Clin Invest
, vol.117
, pp. 1933-1939
-
-
Babitt, J.L.1
Huang, F.W.2
Xia, Y.3
-
9
-
-
85047693999
-
Anemia of inflammation: The cytokine-hepcidin link
-
Andrews NC. Anemia of inflammation: the cytokine-hepcidin link. J Clin Invest 2004; 113: 1251-1253
-
(2004)
J Clin Invest
, vol.113
, pp. 1251-1253
-
-
Andrews, N.C.1
-
10
-
-
30144432585
-
The N-terminus of hepcidin is essential for its interaction with ferroportin: Structure-function study
-
Nemeth E, Preza GC, Jung CL et al. The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood 2006; 107: 328-333
-
(2006)
Blood
, vol.107
, pp. 328-333
-
-
Nemeth, E.1
Preza, G.C.2
Jung, C.L.3
-
11
-
-
0038662619
-
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
-
Nemeth E, Valore EV, Territo M et al. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 2003; 101: 2461-2463
-
(2003)
Blood
, vol.101
, pp. 2461-2463
-
-
Nemeth, E.1
Valore, E.V.2
Territo, M.3
-
12
-
-
4344600507
-
Hepcidin in iron metabolism
-
Ganz T. Hepcidin in iron metabolism. Curr Opin Hematol 2004; 11: 251-254
-
(2004)
Curr Opin Hematol
, vol.11
, pp. 251-254
-
-
Ganz, T.1
-
14
-
-
27144475517
-
Novel urine hepcidin assay by mass spectrometry
-
Kemna E, Tjalsma H, Laarakkers C et al. Novel urine hepcidin assay by mass spectrometry. Blood 2005; 106: 3268-3270
-
(2005)
Blood
, vol.106
, pp. 3268-3270
-
-
Kemna, E.1
Tjalsma, H.2
Laarakkers, C.3
-
15
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ et al. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001; 276: 7806-7810
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
-
16
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001; 98: 8780-8785
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
17
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas G, Bennoun M, Porteu A et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA 2002; 99: 4596-4601
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Porteu, A.3
-
18
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002; 110: 1037-1044
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
19
-
-
33644779127
-
Role of interleukin-6 in hypoxic regulation of intestinal iron absorption
-
Raja KB, Latunde-Dada GO, Peters TJ et al. Role of interleukin-6 in hypoxic regulation of intestinal iron absorption. Br J Haematol 2005; 131: 656-662
-
(2005)
Br J Haematol
, vol.131
, pp. 656-662
-
-
Raja, K.B.1
Latunde-Dada, G.O.2
Peters, T.J.3
-
20
-
-
13844307889
-
Regulation of hepcidin transcription by interleukin-1 and interleukin-6
-
Lee P, Peng H, Gelbart T et al. Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc Natl Acad Sci USA 2005; 102: 1906-1910
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1906-1910
-
-
Lee, P.1
Peng, H.2
Gelbart, T.3
-
21
-
-
33644876815
-
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
-
Wang RH, Li C, Xu X et al. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab 2005; 2: 399-409
-
(2005)
Cell Metab
, vol.2
, pp. 399-409
-
-
Wang, R.H.1
Li, C.2
Xu, X.3
-
22
-
-
38349194098
-
Furin mediated release of soluble hemojuvelin: A new link between hypoxia and iron homeostasis
-
Silvestri L, Pagani A, Camaschella C. Furin mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Blood 2008; 111: 924-931
-
(2008)
Blood
, vol.111
, pp. 924-931
-
-
Silvestri, L.1
Pagani, A.2
Camaschella, C.3
-
23
-
-
34248371666
-
Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis
-
Silvestri L, Pagani A, Fazi C et al. Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. Blood 2007; 109: 4503-4510
-
(2007)
Blood
, vol.109
, pp. 4503-4510
-
-
Silvestri, L.1
Pagani, A.2
Fazi, C.3
-
24
-
-
14944345916
-
Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes
-
Pietrangelo A, Caleffi A, Henrion J et al. Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes. Gastroenterology 2005; 128: 470-479
-
(2005)
Gastroenterology
, vol.128
, pp. 470-479
-
-
Pietrangelo, A.1
Caleffi, A.2
Henrion, J.3
-
25
-
-
1542283709
-
Screening hepcidin for mutations in juvenile hemochromatosis: Identification of a new mutation (C70R)
-
Roetto A, Daraio F, Porporato P et al. Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R). Blood 2004; 103: 2407-2409
-
(2004)
Blood
, vol.103
, pp. 2407-2409
-
-
Roetto, A.1
Daraio, F.2
Porporato, P.3
-
26
-
-
14344249451
-
Hemojuvelin (HJV)-associated hemochromatosis: Analysis of HJV and HFE mutations and iron overload in three families
-
Wallace DF, Dixon JL, Ramm GA et al. Hemojuvelin (HJV)-associated hemochromatosis: analysis of HJV and HFE mutations and iron overload in three families. Haematologica 2005; 90: 254-255
-
(2005)
Haematologica
, vol.90
, pp. 254-255
-
-
Wallace, D.F.1
Dixon, J.L.2
Ramm, G.A.3
-
27
-
-
33947212276
-
Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: Results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) Study
-
Coyne DW, Kapoian T, Suki W et al. Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) Study. J Am Soc Nephrol 2007; 18: 975-984
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 975-984
-
-
Coyne, D.W.1
Kapoian, T.2
Suki, W.3
-
28
-
-
33646345152
-
Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease
-
KDOQI
-
KDOQI. Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease. Am J Kidney Dis 2006; 47: S11-S145
-
(2006)
Am J Kidney Dis
, vol.47
-
-
-
29
-
-
0038777439
-
Safety in iron management
-
Fishbane S. Safety in iron management. Am J Kidney Dis 2003; 41: 18-26
-
(2003)
Am J Kidney Dis
, vol.41
, pp. 18-26
-
-
Fishbane, S.1
-
30
-
-
26444596187
-
The safety of sodium ferric gluconate complex in haemodialysis patients has been extensively evaluated
-
Michael B. The safety of sodium ferric gluconate complex in haemodialysis patients has been extensively evaluated. Nephrol Dial Transplant 2005; 20: 1770
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 1770
-
-
Michael, B.1
-
31
-
-
0029128255
-
Resistance to erythropoietin in iron-overloaded haemodialysis patients can be overcome by ascorbic acid administration
-
Gastaldello K, Vereerstraeten A, Nzame-Nze T et al. Resistance to erythropoietin in iron-overloaded haemodialysis patients can be overcome by ascorbic acid administration. Nephrol Dial Transplant 1995; 10(Suppl 6): 44-47
-
(1995)
Nephrol Dial Transplant
, vol.10
, Issue.SUPPL. 6
, pp. 44-47
-
-
Gastaldello, K.1
Vereerstraeten, A.2
Nzame-Nze, T.3
-
32
-
-
3042663307
-
Pentoxifylline improves hemoglobin levels in patients with erythropoietin-resistant anemia in renal failure
-
Cooper A, Mikhail A, Lethbridge MW et al. Pentoxifylline improves hemoglobin levels in patients with erythropoietin-resistant anemia in renal failure. J Am Soc Nephrol 2004; 15: 1877-1882
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1877-1882
-
-
Cooper, A.1
Mikhail, A.2
Lethbridge, M.W.3
-
33
-
-
33748102856
-
Hepcidin - a peptide hormone at the interface of innate immunity and iron metabolism
-
Ganz T. Hepcidin - a peptide hormone at the interface of innate immunity and iron metabolism. Curr Top Microbiol Immunol 2006; 306: 183-198
-
(2006)
Curr Top Microbiol Immunol
, vol.306
, pp. 183-198
-
-
Ganz, T.1
|