Activation of CCAAT/enhancer-binding protein α or PU.1 in hematopoietic stem cells leads to their reduced self-renewal and proliferation

Stem Cells

Volumn 26, Issue 12, 2008, Pages 3172-3181

  Fukuchi, Yumi ^a   Ito, Miyuki ^a   Shibata, Fumi ^a   Kitamura, Toshio ^a   Nakajima, Hideaki ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CCAAT enhancer binding protein ; Hematopoietic stem cell; PU.1; Self renewal

Indexed keywords

BMI1 PROTEIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; HOX PROTEIN; PROTEIN HOXB4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL FRACTIONATION; CELL LINEAGE; CELL PROLIFERATION; CELL RENEWAL; COLONY FORMATION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; BONE MARROW CELLS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; MICE; MICE, TRANSGENIC; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSGENES;

MUS MUSCULUS;

EID: 58049196594     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0320     Document Type: Article

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