Induction of G2/M arrest and apoptosis by sesquiterpene lactones in human melanoma cell lines

Biochemical Pharmacology

Volumn 75, Issue 2, 2008, Pages 369-382

  Rozenblat, Sharon ^a   Grossman, Shlomo ^a   Bergman, Margalit ^a   Gottlieb, Hugo ^a   Cohen, Yigal ^a   Dovrat, Sara ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

Apoptosis; Chemoresistance; G2 M arrest; Melanoma; Sequiterpene lactones

Indexed keywords

CASPASE 3; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INUVISCOLIDE; MEMBRANE PHOSPHOLIPID; P21 ACTIVATED KINASE; PROTEIN P53; PROTEIN P56; PROTEIN SUBUNIT; SERINE; SESQUITERPENE LACTONE DERIVATIVE; SURVIVIN; THREONINE; TOMENTOSIN; TRANSCRIPTION FACTOR RELA; TYROSINE; UNCLASSIFIED DRUG; LACTONE; PLANT EXTRACT; SESQUITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG PURIFICATION; EMBRYO INDUCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INULA; INULA VISCOSA; MELANOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; CELL DIVISION; CELL MEMBRANE POTENTIAL; DRUG EFFECT; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

APOPTOSIS; CASPASE 3; CDC2 PROTEIN KINASE; CELL DIVISION; CELL LINE, TUMOR; G2 PHASE; HUMANS; INULA; LACTONES; MELANOMA; MEMBRANE POTENTIALS; NF-KAPPA B; PHOSPHORYLATION; PLANT EXTRACTS; SESQUITERPENES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 37349021483     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.08.024     Document Type: Article

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