Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats

Journal of Hepatology

Volumn 41, Issue 2, 2004, Pages 242-250

  Imanishi, Yukihiro ^a   Maeda, Naoto ^a   Otogawa, Kohji ^a   Seki, Shuichi ^a   Matsui, Hiroko ^a   Kawada, Norifumi ^a   Arakawa, Tetsuo ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

BrdU, 5 bromo 2 deoxyuridine; Cell proliferation; CMC, carboxymethylcellulose; Collagen; DAB, 3,3 diaminobenzidine tetrahydrochloride; ECM, extracellular matrix; Migration; Mitogen activated protein kinase; Traditional Chinese medicine

Indexed keywords

ALPHA ACTIN; ARTEMISIAE CAPILLARI SPICA EXTRACT; BROXURIDINE; CINNAMIC ACID; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; EMODIN; FIBRONECTIN; GARDENIAE FRUCTUS EXTRACT; HERBACEOUS AGENT; HYALURONIC ACID; INCHIN KO TO; INCHINKO TO; PLANT EXTRACT; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RHUBARB EXTRACT; THIOACETAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL MIGRATION; CHINESE HERB; CHINESE MEDICINE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; LIVER CELL CULTURE; LIVER FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; WESTERN BLOTTING;

ACTINS; ANIMALS; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; DNA; DRUGS, CHINESE HERBAL; EMODIN; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MUSCLE, SMOOTH; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, WISTAR; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; THIOACETAMIDE;

EID: 4444303261     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.04.005     Document Type: Article

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