Structural elucidation of a PDE-5 inhibitor detected as an adulterant in a health supplement

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 4, 2008, Pages 1070-1075

  Ge, Xiaowei ^a   Low, Min Yong ^a   Zou, Peng ^a   Lin, Li ^b   Yin, Sharon Oh Sze ^a   Bloodworth, Bosco C ^a   Koh, Hwee Ling ^b  

^a HEALTH SCIENCES AUTHORITY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Adulterant; Health supplement; Liquid chromatography (LC); Mass spectrometry (MS); Nuclear magnetic resonance (NMR); PDE 5 inhibitor

Indexed keywords

8 [2 (4 (HYDROXYMETHYL)PIPERIDIN 1 YL]BENZYLAMINO] 3 ETHYL 1H IMIDAZO[4,5 G]QUINAZOLINE 2(3H) THIONE; KF 31327; PHOSPHODIESTERASE V INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG DETERMINATION; DRUG IMPURITY; DRUG ISOLATION; DRUG STRUCTURE; INFRARED SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

CAPSULES; CHROMATOGRAPHY, LIQUID; DIETARY SUPPLEMENTS; DRUG CONTAMINATION; ERECTILE DYSFUNCTION; HUMANS; IMIDAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MOLECULAR STRUCTURE; PHOSPHODIESTERASE INHIBITORS; QUINAZOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 57849096122     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.08.019     Document Type: Article

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