Vascular endothelium in cancer

Cell and Tissue Research

Volumn 335, Issue 1, 2009, Pages 223-240

  Nikitenko, Leonid L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Angiogenesis; Cancer; Endothelial cell; Kaposi's sarcoma; Lymphangiogenesis; Neoplasm

Indexed keywords

ANGIOPOIETIN 2; ANTIRETROVIRUS AGENT; BEVACIZUMAB; BORTEZOMIB; CETUXIMAB; CYCLOSPORIN; DAUNORUBICIN; DOXORUBICIN; ERLOTINIB; IMATINIB; PACLITAXEL; RAPAMYCIN; SORAFENIB; THALIDOMIDE; TRASTUZUMAB; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANGIOGENESIS; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CELL DIFFERENTIATION; CELL FUNCTION; CELL HETEROGENEITY; CELL INTERACTION; CELL LINEAGE; CELL PROLIFERATION; CELL TRANSFORMATION; CLINICAL TRIAL; CONGENITAL BLOOD VESSEL MALFORMATION; DISEASE ACTIVITY; DRUG SUBSTITUTION; DRUG TARGETING; ENDOTHELIUM CELL; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOMEOSTASIS; HUMAN; KAPOSI SARCOMA; LYMPHANGIOGENESIS; MALIGNANT NEOPLASTIC DISEASE; METASTASIS; MOLECULAR DYNAMICS; MORPHOGENESIS; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; ORGANOGENESIS; PATHOGENESIS; PATHOPHYSIOLOGY; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; STROMA CELL; TISSUE SPECIFICITY; TUMOR GROWTH; TUMOR RESISTANCE; TUMOR VASCULARIZATION; VASCULAR ENDOTHELIUM;

ANIMALS; DRUG RESISTANCE, NEOPLASM; ENDOTHELIUM, VASCULAR; HOMEOSTASIS; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; ORGANOGENESIS;

EID: 57749176665     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-008-0707-4     Document Type: Review

References (74)

1. RH Adams K Alitalo 2007 Molecular regulation of angiogenesis and lymphangiogenesis Nat Rev Mol Cell Biol 8 464 478
2. A Alajati AM Laib H Weber AM Boos A Bartol K Ikenberg T Korff H Zentgraf C Obodozie R Graeser S Christian G Finkenzeller GB Stark M Héroult HG Augustin 2008 Spheroid-based engineering of a human vasculature in mice Nat Methods 5 439 445
3. K Alitalo P Carmeliet 2002 Molecular mechanisms of lymphangiogenesis in health and disease Cancer Cell 1 219 227
4. K Alitalo T Tammela TV Petrova 2005 Lymphangiogenesis in development and human disease Nature 438 946 953
5. T Asahara T Murohara A Sullivan M Silver R van der Zee T Li B Witzenbichler G Schatteman JM Isner 1997 Isolation of putative progenitor endothelial cells for angiogenesis Science 275 964 967
6. W Arap MG Kolonin M Trepel J Lahdenranta M Cardó-Vila RJ Giordano PJ Mintz PU Ardelt VJ Yao CI Vidal L Chen A Flamm H Valtanen LM Weavind ME Hicks RE Pollock GH Botz CD Bucana E Koivunen D Cahill P Troncoso KA Baggerly RD Pentz KA Do CJ Logothetis R Pasqualini 2002 Steps toward mapping the human vasculature by phage display Nat Med 8 121 127
7. C Bais B Santomasso O Coso L Arvanitakis EG Raaka JS Gutkind AS Asch E Cesarman MC Gershengorn EA Mesri 1998 G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator Nature 391 86 89
8. S Bandyopadhyay R Zhan A Chaudhuri M Watabe SK Pai S Hirota S Hosobe T Tsukada K Miura Y Takano K Saito ME Pauza S Hayashi Y Wang S Mohinta T Mashimo M Iiizumi E Furuta K Watabe 2006 Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression Nat Med 12 933 938
9. P Bianco PG Robey PJ Simmons 2008 Mesenchymal stem cells: revisiting history, concepts, and assays Cell Stem Cell 2 313 319
10. C Boshoff R Weiss 2002 AIDS-related malignancies Nat Rev Cancer 2 373 382
11. C Boshoff Y Endo PD Collins Y Takeuchi JD Reeves VL Schweickart MA Siani T Sasaki TJ Williams PW Gray PS Moore Y Chang RA Weiss 1997 Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines Science 278 290 294
12. LF Brown BJ Dezube K Tognazzi HF Dvorak GD Yancopoulos 2000 Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma Am J Pathol 156 2179 2183
13. F Bruyère L Melen-Lamalle S Blacher G Roland M Thiry L Moons F Frankenne P Carmeliet K Alitalo C Libert JP Sleeman JM Foidart A Noël 2008 Modeling lymphangiogenesis in a three-dimensional culture system Nat Methods 5 431 437
14. C Calabrese H Poppleton M Kocak TL Hogg C Fuller B Hamner EY Oh MW Gaber D Finklestein M Allen A Frank IT Bayazitov SS Zakharenko A Gajjar A Davidoff RJ Gilbertson 2007 A perivascular niche for brain tumor stem cells Cancer Cell 11 69 82
15. P Carmeliet 2003 Angiogenesis in health and disease Nat Med 9 653 660
16. P Carmeliet 2005 Angiogenesis in life, disease and medicine Nature 438 932 936
17. P Carmeliet RK Jain 2000 Angiogenesis in cancer and other diseases Nature 407 249 257
18. JT Chi HY Chang G Haraldsen FL Jahnsen OG Troyanskaya DS Chang Z Wang SG Rockson M van de Rijn D Botstein PO Brown 2003 Endothelial cell diversity revealed by global expression profiling Proc Natl Acad Sci USA 100 10623 10628
19. J Condeelis JW Pollard 2006 Macrophages: obligate partners for tumor cell migration, invasion, and metastasis Cell 124 262 266
20. JR Conejo-Garcia F Benencia MC Courreges E Kang A Mohamed-Hadley RJ Buckanovich DO Holtz A Jenkins H Na L Zhang DS Wagner D Katsaros R Caroll G Coukos 2004 Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of VEGF-A Nat Med 10 950 958
21. S Della Bella A Taddeo ML Calabrò L Brambilla M Bellinvia E Bergamo M Clerici ML Villa 2008 Peripheral blood endothelial progenitors as potential reservoirs of Kaposi's sarcoma-associated herpesvirus PLoS ONE 3 e1520
22. M De Palma MA Venneri C Roca L Naldini 2003 Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells Nat Med 9 789 795
23. EA Engels RM Pfeiffer JJ Goedert P Virgo TS McNeel SM Scoppa RJ Biggar for the HIV/AIDS Cancer Match Study 2006 Trends in cancer risk among people with AIDS in the United States 1980-2002 AIDS 20 1645 1654
24. S Euvrard J Kanitakis A Claudy 2003 Skin cancers after organ transplantation N Engl J Med 348 1681 1691
25. N Ferrara RS Kerbel 2005 Angiogenesis as a therapeutic target Nature 438 967 974
26. C Folkins S Man P Xu Y Shaked DJ Hicklin RS Kerbel 2007 Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors Cancer Res 67 3560 3564
27. J Folkman 1971 Tumor angiogenesis: therapeutic implications N Engl J Med 285 1182 1186
28. Folkman J (2000) Tumour angiogenesis. In: Holland JF, Frei E, Bast RC, Kufe DW, Morton DL, Weichselbaum RR (eds) Cancer medicine. Decker, Ontario, pp 132-152
29. NW Gale G Thurston S Davis SJ Wiegand J Holash JS Rudge GD Yancopoulos 2002 Complementary and coordinated roles of the VEGFs and angiopoietins during normal and pathologic vascular formation Cold Spring Harb Symp Quant Biol 67 267 273
30. D Galli A Innocenzi L Staszewsky L Zanetta M Sampaolesi A Bai E Martinoli E Carlo G Balconi F Fiordaliso S Chimenti G Cusella E Dejana G Cossu R Latini 2005 Mesoangioblasts, vessel-associated multipotent stem cells, repair the infarcted heart by multiple cellular mechanisms: a comparison with bone marrow progenitors, fibroblasts, and endothelial cells Arterioscler Thromb Vasc Biol 25 692 697
31. A Gessain R Duprez 2005 Spindle cells and their role in Kaposi's sarcoma Int J Biochem Cell Biol 37 2457 2465
32. D Hanahan RA Weinberg 2000 The hallmarks of cancer Cell 100 57 70
33. A Hansen C Boshoff D Lagos 2007 Kaposi sarcoma as a model of oncogenesis and cancer treatment Expert Rev Anticancer Ther 7 211 220
34. YK Hong K Foreman JW Shin S Hirakawa CL Curry DR Sage T Libermann BJ Dezube JD Fingeroth M Detmar 2004 Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus Nat Genet 36 683 685
35. H Hurwitz L Fehrenbacher W Novotny T Cartwright J Hainsworth W Heim 2004 Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer New Engl J Med 350 2335 2342
36. RK Jain 1996 Delivery of molecular medicine to solid tumors Science 271 1079 1080
37. RK Jain 2008 Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer Nat Rev Cancer 8 309 316
38. RK Jain GC Koenig M Dellian D Fukumura LL Munn RJ Melder 1996 Leukocyte-endothelial adhesion and angiogenesis in tumors Cancer Metastasis Rev 15 195 204
39. D Karnoub AB Dash AP Vo A Sullivan MW Brooks GW Bell AL Richardson K Polyak R Tubo RA Weinberg 2007 Mesenchymal stem cells within tumour stroma promote breast cancer metastasis Nature 449 557 563
40. RS Kerbel J Folkman 2002 Clinical translation of angiogenesis inhibitors Nat Rev Cancer 2 727 739
41. D Kerjaschki N Huttary I Raab H Regele K Bojarski-Nagy G Bartel SM Krober H Greinix A Rosenmaier F Karlhofer N Wick PR Mazal 2006 Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants Nat Med 12 230 234
42. HB Koon GJ Bubley L Pantanowitz D Masiello B Smith K Crosby J Proper W Weeden TE Miller P Chatis MJ Egorin SR Tahan BJ Dezube 2005 Imatinib-induced regression of AIDS-related Kaposi's sarcoma J Clin Oncol 23 982 989
43. RR Langley IJ Fidler 2007 Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis Endocr Rev 28 297 321
44. J LeCouter R Lin N Ferrara 2002 Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis Nat Med 8 913 917
45. ND Lawson N Scheer VN Pham CH Kim AB Chitnis JA Campos-Ortega BM Weinstein 2001 Notch signaling is required for arterial-venous differentiation during embryonic vascular development Development 128 3675 3683
46. ND Lawson AM Vogel BM Weinstein 2002 Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation Dev Cell 3 127 136
47. R Masood J Cai T Zheng DL Smith Y Naidu PS Gill 1997 Vascular endothelial growth factor/vascular permeability factor is an autocrine growth factor for AIDS-Kaposi sarcoma Proc Natl Acad Sci USA 94 979 984
48. Moncada S (2006) Nitric oxide and the vascular endothelium. In: Moncada S, Higgs A (eds) Handbook of Experimental Pharmacology, vol 176. The vascular endothelium. Springer, Berlin Heidelberg New York, pp 213-254
49. AD Mutlu LE Cavallin L Vincent C Chiozzini P Eroles EM Duran Z Asgari AT Hooper KM La Perle C Hilsher SJ Gao DP Dittmer S Rafii EA Mesri 2007 In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma Cancer Cell 11 245 258
50. J Oliner H Min J Leal D Yu S Rao E You X Tang H Kim S Meyer SJ Han N Hawkins R Rosenfeld E Davy K Graham F Jacobsen S Stevenson J Ho Q Chen T Hartmann M Michaels M Kelley L Li K Sitney F Martin JR Sun N Zhang J Lu J Estrada R Kumar A Coxon S Kaufman J Pretorius S Scully R Cattley M Payton S Coats L Nguyen B Desilva A Ndifor I Hayward R Radinsky T Boone R Kendall 2004 Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2 Cancer Cell 6 507 516
51. Nikitenko LL, Boshoff C (2006) Endothelial cells and cancer. In: Moncada S, Higgs A (eds) Handbook of Experimental Pharmacology, vol 176. The vascular endothelium. Springer, Berlin Heidelberg New York, pp 637-664
52. LL Nikitenko SB Fox S Kehoe MCP Rees R Bicknell 2006 Adrenomedullin and tumor angiogenesis Br J Cancer 94 1 7
53. A Ny M Koch M Schneider E Neven RT Tong S Maity C Fischer S Plaisance D Lambrechts C Héligon S Terclavers M Ciesiolka R Kälin WY Man I Senn S Wyns F Lupu A Brändli K Vleminckx D Collen M Dewerchin EM Conway L Moons RK Jain P Carmeliet 2005 A genetic Xenopus laevis tadpole model to study lymphangiogenesis Nat Med 11 9 998 1004
54. A Orimo PB Gupta DC Sgroi F Arenzana-Seisdedos T Delaunay R Naeem VJ Carey AL Richardson RA Weinberg 2005 Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion Cell 121 335 348
55. TP Padera A Kadambi E di Tomaso CM Carreira EB Brown Y Boucher NC Choi D Mathisen J Wain EJ Mark LL Munn RK Jain 2002 Lymphatic metastasis in the absence of functional intratumor lymphatics Science 296 1883 1886
56. D Padua XH Zhang Q Wang C Nadal WL Gerald RR Gomis J Massagué 2008 TGF-beta primes breast tumors for lung metastasis seeding through angiopoietin-like 4 Cell 133 66 77
57. S Pati CB Pelser J Dufraine JL Bryant MS Reitz Jr FF Weichold 2002 Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma Blood 99 3771 3779
58. BN Perry B Govindarajan SS Bhandarkar UG Knaus M Valo C Sturk CO Carrillo A Sohn F Cerimele D Dumont A Losken J Williams LF Brown X Tan E Ioffe GD Yancopoulos JL Arbiser 2006 Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice J Invest Dermatol 126 2316 2322
59. BA Peters LA Diaz K Polyak L Meszler K Romans EC Guinan JH Antin D Myerson SR Hamilton B Vogelstein KW Kinzler C Lengauer 2005 Contribution of bone marrow-derived endothelial cells to human tumor vasculature Nat Med 11 261 262
60. DC Rafii B Psaila J Butler DK Jin D Lyden 2008 Regulation of vasculogenesis by platelet-mediated recruitment of bone marrow-derived cells Arterioscler Thromb Vasc Biol 28 217 222
61. K Red-Horse Y Crawford F Shojaei N Ferrara 2007 Endothelium- microenvironment interactions in the developing embryo and in the adult Dev Cell 12 181 194
62. MR Ritter MI Dorrell J Edmonds SF Friedlander M Friedlander 2002 Insulin-like growth factor 2 and potential regulators of hemangioma growth and involution identified by large-scale expression analysis Proc Natl Acad Sci USA 99 7455 7460
63. S Seaman J Stevens MY Yang D Logsdon C Graff-Cherry B St Croix 2007 Genes that distinguish physiological and pathological angiogenesis Cancer Cell 11 539 554
64. C Sgadari G Barillari E Toschi D Carlei I Bacigalupo S Baccarini C Palladino P Leone R Bugarini L Malavasi A Cafaro M Falchi D Valdembri G Rezza F Bussolino P Monini B Ensoli 2002 HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma Nat Med 8 225 232
65. A Sodhi R Chaisuparat J Hu AK Ramsdell BD Manning EA Sausville ET Sawai A Molinolo JS Gutkind S Montaner 2006 The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor Cancer Cell 10 133 143
66. H Spring T Schüler B Arnold GJ Hämmerling R Ganss 2005 Chemokines direct endothelial progenitors into tumor neovessels Proc Natl Acad Sci USA 102 18111 18116
67. G Stallone A Schena B Infante S Di Paolo A Loverre G Maggio E Ranieri L Gesualdo FP Schena G Grandaliano 2005 Sirolimus for Kaposi's sarcoma in renal-transplant recipients N Engl J Med 352 1317 1323
68. A Taddeo P Presicce L Brambilla M Bellinvia ML Villa S Della Bella 2008 Circulating endothelial progenitor cells are increased in patients with classic Kaposi's sarcoma J Invest Dermatol 128 2125 2128
69. RJ Vart LL Nikitenko D Lagos MW Trotter M Cannon D Bourboulia F Gratrix Y Takeuchi C Boshoff 2007 Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells Cancer Res 67 4042 4051
70. HW Wang MW Trotter D Lagos D Bourboulia S Henderson T Makinen S Elliman AM Flanagan K Alitalo C Boshoff 2004 Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma Nat Genet 36 687 693
71. J Wilting Y Aref R Huang SI Tomarev L Schweigerer B Christ P Valasek M Papoutsi 2006 Dual origin of avian lymphatics Dev Biol 292 165 173
72. K Yaniv S Isogai D Castranova L Dye J Hitomi BM Weinstein 2006 Live imaging of lymphatic development in the zebrafish Nat Med 12 711 716
73. TP Zhong S Childs JP Leu MC Fishman 2001 Gridlock signalling pathway fashions the first embryonic artery Nature 414 216 220
74. A Zlotnik 2004 Chemokines in neoplastic progression Semin Cancer Biol 14 181 185