Over-expression of a modified bifunctional apoptosis regulator protects against cardiac injury and doxorubicin-induced cardiotoxicity in transgenic mice

Cardiovascular Research

Volumn 81, Issue 1, 2009, Pages 20-27

  Chua, Chu Chang ^a   Gao, Jinping ^a   Ho, Ye Shih ^b   Xu, Xingshun ^a   Kuo, I Chun ^c   Chua, Kaw Yan ^c   Wang, Hong ^a   Hamdy, Ronald C ^a   Reed, John C ^d   Chua, Balvin H L ^a  

^a EAST TENNESSEE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d BURNHAM INSTITUTE   (United States)

Author keywords

BAR; Cardiac apoptosis; Doxorubicin induced cardiotoxicity; Ischaemia reperfusion injury; Transgenic mice

Indexed keywords

AMINO ACID; BIFUNCTIONAL APOPTOSIS REGULATOR; DOXORUBICIN; MYOSIN HEAVY CHAIN ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY LIGATION; EX VIVO STUDY; FEMALE; HEART INFARCTION SIZE; HEART INJURY; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RATE; HEART VENTRICLE PRESSURE; IN VIVO STUDY; ISOLATED HEART; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; REPERFUSION INJURY; RING FINGER MOTIF; TRANSGENE; TRANSGENIC MOUSE; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CALCIUM; DISEASE MODELS, ANIMAL; DOXORUBICIN; HEART DISEASES; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PROTEASOME ENDOPEPTIDASE COMPLEX; RING FINGER DOMAINS; UBIQUITIN;

EID: 57749172871     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn257     Document Type: Article

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