메뉴 건너뛰기




Volumn 6, Issue 12, 2008, Pages 1937-1945

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; AURORA B KINASE; EWS FLI1 FUSION PROTEIN; GENE PRODUCT; HYBRID PROTEIN; LUCIFERASE; MESSENGER RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 57749101153     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0054     Document Type: Article
Times cited : (43)

References (57)
  • 1
    • 0028074607 scopus 로고
    • The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains
    • Ohno T, Ouchida M, Lee L, Gatalica Z, Rao VN, Reddy ES. The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains. Oncogene 1994;9:3087-97.
    • (1994) Oncogene , vol.9 , pp. 3087-3097
    • Ohno, T.1    Ouchida, M.2    Lee, L.3    Gatalica, Z.4    Rao, V.N.5    Reddy, E.S.6
  • 2
    • 0027197554 scopus 로고
    • Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein
    • Rao VN, Ohno T, Prasad DD, Bhattacharya G, Reddy ES. Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein. Oncogene 1993;8:2167-73.
    • (1993) Oncogene , vol.8 , pp. 2167-2173
    • Rao, V.N.1    Ohno, T.2    Prasad, D.D.3    Bhattacharya, G.4    Reddy, E.S.5
  • 4
    • 0026335817 scopus 로고
    • erg, an ets-related gene, codes for sequence-specific transcriptional activators
    • Reddy ES, Rao VN. erg, an ets-related gene, codes for sequence-specific transcriptional activators. Oncogene 1991;6:2285-89.
    • (1991) Oncogene , vol.6 , pp. 2285-2289
    • Reddy, E.S.1    Rao, V.N.2
  • 5
    • 0035839938 scopus 로고    scopus 로고
    • Biology of EWS/ETS fusions in Ewing's family tumors
    • Arvand A, Denny CT. Biology of EWS/ETS fusions in Ewing's family tumors. Oncogene 2001;20:5747-54.
    • (2001) Oncogene , vol.20 , pp. 5747-5754
    • Arvand, A.1    Denny, C.T.2
  • 6
    • 0035393826 scopus 로고    scopus 로고
    • The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1
    • Arvand A, Welford SM, Teitell MA, Denny CT. The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1. Cancer Res 2001;61:5311-7.
    • (2001) Cancer Res , vol.61 , pp. 5311-5317
    • Arvand, A.1    Welford, S.M.2    Teitell, M.A.3    Denny, C.T.4
  • 7
    • 4544268945 scopus 로고    scopus 로고
    • ETS transcription factors: Possible targets for cancer therapy
    • Oikawa T. ETS transcription factors: possible targets for cancer therapy. Cancer Sci 2004;95:626-33.
    • (2004) Cancer Sci , vol.95 , pp. 626-633
    • Oikawa, T.1
  • 8
    • 0037448612 scopus 로고    scopus 로고
    • Molecular biology of the Ets family of transcription factors
    • Oikawa, T, Yamada T. Molecular biology of the Ets family of transcription factors. Gene 2003;303:11-34.
    • (2003) Gene , vol.303 , pp. 11-34
    • Oikawa, T.1    Yamada, T.2
  • 9
    • 0030894642 scopus 로고    scopus 로고
    • Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias
    • Yi H, Fujimura Y, Ouchida M, Prasad DD, Rao VN, Reddy ES. Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias. Oncogene 1997;14:1259-68.
    • (1997) Oncogene , vol.14 , pp. 1259-1268
    • Yi, H.1    Fujimura, Y.2    Ouchida, M.3    Prasad, D.D.4    Rao, V.N.5    Reddy, E.S.6
  • 10
    • 0028913803 scopus 로고
    • Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene
    • Sorensen PH, Shimada H, Liu XF, Lim JF, Thomas G, Triche TJ. Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene. Cancer Res 1995;55:1385-92.
    • (1995) Cancer Res , vol.55 , pp. 1385-1392
    • Sorensen, P.H.1    Shimada, H.2    Liu, X.F.3    Lim, J.F.4    Thomas, G.5    Triche, T.J.6
  • 11
    • 0028826420 scopus 로고
    • Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts
    • Ouchida M, Ohno T, Fujimura Y, Rao VN, Reddy ES. Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts. Oncogene 1995;11:1049-54.
    • (1995) Oncogene , vol.11 , pp. 1049-1054
    • Ouchida, M.1    Ohno, T.2    Fujimura, Y.3    Rao, V.N.4    Reddy, E.S.5
  • 12
    • 44849085869 scopus 로고    scopus 로고
    • EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma. PLoS ONE
    • 3:e1965
    • Owen LA, Kowalewski AA, Lessnick SL. EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma. PLoS ONE 2008;3:e1965.
    • (2008)
    • Owen, L.A.1    Kowalewski, A.A.2    Lessnick, S.L.3
  • 13
    • 34547097800 scopus 로고    scopus 로고
    • EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins
    • Potikyan G, Savene RO, Gaulden JM, et al. EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins. Cancer Res 2007;67:6675-84.
    • (2007) Cancer Res , vol.67 , pp. 6675-6684
    • Potikyan, G.1    Savene, R.O.2    Gaulden, J.M.3
  • 14
    • 33646366123 scopus 로고    scopus 로고
    • Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma
    • Smith R, Owen LA, Trem DJ, et al. Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Cancer Cell 2006;9:405-16.
    • (2006) Cancer Cell , vol.9 , pp. 405-416
    • Smith, R.1    Owen, L.A.2    Trem, D.J.3
  • 15
    • 33845344030 scopus 로고    scopus 로고
    • NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma
    • Kinsey M, Smith R, Lessnick SL. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma. Mol Cancer Res 2006;4:851-9.
    • (2006) Mol Cancer Res , vol.4 , pp. 851-859
    • Kinsey, M.1    Smith, R.2    Lessnick, S.L.3
  • 16
    • 17844370020 scopus 로고    scopus 로고
    • PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's sarcoma tumorigenesis
    • Abaan OD, Levenson A, Khan O, Furth PA, Uren A, Toretsky JA. PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's sarcoma tumorigenesis. Oncogene 2005;24:2715-22.
    • (2005) Oncogene , vol.24 , pp. 2715-2722
    • Abaan, O.D.1    Levenson, A.2    Khan, O.3    Furth, P.A.4    Uren, A.5    Toretsky, J.A.6
  • 17
    • 0037994344 scopus 로고    scopus 로고
    • B-Platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells
    • Uren A, Merchant MS, Sun CJ, et al. B-Platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells. Oncogene 2003;22:2334-42.
    • (2003) Oncogene , vol.22 , pp. 2334-2342
    • Uren, A.1    Merchant, M.S.2    Sun, C.J.3
  • 18
    • 10744231438 scopus 로고    scopus 로고
    • EWS/ETS fusions activate telomerase in Ewing's tumors
    • Takahashi A, Higashino F, Aoyagi M, et al. EWS/ETS fusions activate telomerase in Ewing's tumors. Cancer Res 2003;63:8338-44.
    • (2003) Cancer Res , vol.63 , pp. 8338-8344
    • Takahashi, A.1    Higashino, F.2    Aoyagi, M.3
  • 19
    • 0037427070 scopus 로고    scopus 로고
    • Upregulation of Id2, an oncogenic helix-loop-helix protein, is mediated by the chimeric EWS/ets protein in Ewing sarcoma
    • Fukuma M, Okita H, Hata J, Umezawa A. Upregulation of Id2, an oncogenic helix-loop-helix protein, is mediated by the chimeric EWS/ets protein in Ewing sarcoma. Oncogene 2003;22:1-9.
    • (2003) Oncogene , vol.22 , pp. 1-9
    • Fukuma, M.1    Okita, H.2    Hata, J.3    Umezawa, A.4
  • 20
    • 0041672262 scopus 로고    scopus 로고
    • Functional analysis of the EWS/ETS target gene uridine phosphorylase
    • Deneen B, Hamidi H, Denny CT. Functional analysis of the EWS/ETS target gene uridine phosphorylase. Cancer Res 2003;63:4268-74.
    • (2003) Cancer Res , vol.63 , pp. 4268-4274
    • Deneen, B.1    Hamidi, H.2    Denny, C.T.3
  • 21
    • 0033988179 scopus 로고    scopus 로고
    • Preferential down-regulation of phospholipase C-β in Ewing's sarcoma cells transfected with antisense EWS-Fli1
    • Dohjima T, Ohno T, Banno Y, et al. Preferential down-regulation of phospholipase C-β in Ewing's sarcoma cells transfected with antisense EWS-Fli1. Br J Cancer 2000;82:16-9.
    • (2000) Br J Cancer , vol.82 , pp. 16-19
    • Dohjima, T.1    Ohno, T.2    Banno, Y.3
  • 22
    • 0030707948 scopus 로고    scopus 로고
    • EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic
    • May WA, Arvand A, Thompson AD, et al. EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic. Nat Genet 1997;17:495-7.
    • (1997) Nat Genet , vol.17 , pp. 495-497
    • May, W.A.1    Arvand, A.2    Thompson, A.D.3
  • 23
    • 0032848660 scopus 로고    scopus 로고
    • Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein
    • Hahm KB, Cho K, Lee C, et al. Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein. Nat Genet 1999;23:222-7.
    • (1999) Nat Genet , vol.23 , pp. 222-227
    • Hahm, K.B.1    Cho, K.2    Lee, C.3
  • 24
    • 33947236885 scopus 로고    scopus 로고
    • The suppression of aurora-A/STK15/ BTAK expression enhances chemosensitivity to docetaxel in human esophageal squamous cell carcinoma
    • Tanaka E, Hashimoto Y, Ito T, et al. The suppression of aurora-A/STK15/ BTAK expression enhances chemosensitivity to docetaxel in human esophageal squamous cell carcinoma. Clin Cancer Res 2007;13:1331-40.
    • (2007) Clin Cancer Res , vol.13 , pp. 1331-1340
    • Tanaka, E.1    Hashimoto, Y.2    Ito, T.3
  • 25
    • 34547135182 scopus 로고    scopus 로고
    • Predictive value of Aurora-A/STK15 expression for late stage epithelial ovarian cancer patients treated by adjuvant chemotherapy
    • Lassmann S, Shen Y, Jutting U, et al. Predictive value of Aurora-A/STK15 expression for late stage epithelial ovarian cancer patients treated by adjuvant chemotherapy. Clin Cancer Res 2007;13:4083-91.
    • (2007) Clin Cancer Res , vol.13 , pp. 4083-4091
    • Lassmann, S.1    Shen, Y.2    Jutting, U.3
  • 26
    • 33645515866 scopus 로고    scopus 로고
    • Global gene expression profiling of pleural mesotheliomas: Overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction
    • Lopez-Rios F, Chuai S, Flores R, et al. Global gene expression profiling of pleural mesotheliomas: overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction. Cancer Res 2006;66:2970-9.
    • (2006) Cancer Res , vol.66 , pp. 2970-2979
    • Lopez-Rios, F.1    Chuai, S.2    Flores, R.3
  • 27
    • 33744911634 scopus 로고    scopus 로고
    • Targeting Aurora kinases for the treatment of prostate cancer
    • Lee EC, Frolov A, Li R, Ayala G, Greenberg NM. Targeting Aurora kinases for the treatment of prostate cancer. Cancer Res 2006;66:4996-5002.
    • (2006) Cancer Res , vol.66 , pp. 4996-5002
    • Lee, E.C.1    Frolov, A.2    Li, R.3    Ayala, G.4    Greenberg, N.M.5
  • 28
    • 33746905089 scopus 로고    scopus 로고
    • AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer
    • Furukawa T, Kanai N, Shiwaku HO, Soga N, Uehara A, Horii A. AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer. Oncogene 2006;25:4831-9.
    • (2006) Oncogene , vol.25 , pp. 4831-4839
    • Furukawa, T.1    Kanai, N.2    Shiwaku, H.O.3    Soga, N.4    Uehara, A.5    Horii, A.6
  • 29
    • 5144233514 scopus 로고    scopus 로고
    • Centrosome hyperamplification predicts progression and tumor recurrence in bladder cancer
    • Yamamoto Y, Matsuyama H, Furuya T, et al. Centrosome hyperamplification predicts progression and tumor recurrence in bladder cancer. Clin Cancer Res 2004;10:6449-55.
    • (2004) Clin Cancer Res , vol.10 , pp. 6449-6455
    • Yamamoto, Y.1    Matsuyama, H.2    Furuya, T.3
  • 30
    • 1642361744 scopus 로고    scopus 로고
    • Overexpression and amplification of Aurora-A in hepatocellular carcinoma
    • Jeng YM, Peng SY, Lin CY, Hsu HC. Overexpression and amplification of Aurora-A in hepatocellular carcinoma. Clin Cancer Res 2004;10:2065-71.
    • (2004) Clin Cancer Res , vol.10 , pp. 2065-2071
    • Jeng, Y.M.1    Peng, S.Y.2    Lin, C.Y.3    Hsu, H.C.4
  • 31
    • 0037663344 scopus 로고    scopus 로고
    • Aneuploidy of human testicular germ cell tumors is associated with amplification of centrosomes
    • Mayer F, Stoop H, Sen S, et al. Aneuploidy of human testicular germ cell tumors is associated with amplification of centrosomes. Oncogene 2003;22:3859-66.
    • (2003) Oncogene , vol.22 , pp. 3859-3866
    • Mayer, F.1    Stoop, H.2    Sen, S.3
  • 32
    • 0037019736 scopus 로고    scopus 로고
    • Amplification/overexpression of a mitotic kinase gene in human bladder cancer
    • Sen S, Zhou H, Zhang RD, et al. Amplification/overexpression of a mitotic kinase gene in human bladder cancer. J Natl Cancer Inst 2002;94:1320-9.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1320-1329
    • Sen, S.1    Zhou, H.2    Zhang, R.D.3
  • 33
    • 0033756439 scopus 로고    scopus 로고
    • Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers
    • Takahashi T, Futamura M, Yoshimi N, et al. Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers. Jpn J Cancer Res 2000;91:1007-14.
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1007-1014
    • Takahashi, T.1    Futamura, M.2    Yoshimi, N.3
  • 34
    • 0033135640 scopus 로고    scopus 로고
    • Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast
    • Tanaka T, Kimura M, Matsunaga K, Fukada D, Mori H, Okano Y. Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res 1999;59:2041-4.
    • (1999) Cancer Res , vol.59 , pp. 2041-2044
    • Tanaka, T.1    Kimura, M.2    Matsunaga, K.3    Fukada, D.4    Mori, H.5    Okano, Y.6
  • 35
    • 0031714080 scopus 로고    scopus 로고
    • Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
    • Zhou H, Kuang J, Sen S, et al. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 1998;20:189-93.
    • (1998) Nat Genet , vol.20 , pp. 189-193
    • Zhou, H.1    Kuang, J.2    Sen, S.3
  • 36
    • 0031421053 scopus 로고    scopus 로고
    • Assignment of STK6 to human chromosome 20q13.2→q13.3 and a pseudogene STK6P to 1q41→q42
    • Kimura M, Matsuda Y, Okano Y, et al. Assignment of STK6 to human chromosome 20q13.2→q13.3 and a pseudogene STK6P to 1q41→q42. Cytogenet Cell Genet 1997;79:201-3.
    • (1997) Cytogenet Cell Genet , vol.79 , pp. 201-203
    • Kimura, M.1    Matsuda, Y.2    Okano, Y.3
  • 37
    • 0030946109 scopus 로고    scopus 로고
    • Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1
    • Kimura M, Kotani S, Okano Y, et al. Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. J Biol Chem 1997;272:13766-71.
    • (1997) J Biol Chem , vol.272 , pp. 13766-13771
    • Kimura, M.1    Kotani, S.2    Okano, Y.3
  • 38
    • 0032408639 scopus 로고    scopus 로고
    • Identification and characterization of STK12/Aik2: A human gene related to aurora of Drosophila and yeast IPL1
    • Kimura M, Matsuda Y, Yoshioka T, Sumi N, Okano Y. Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1. Cytogenet Cell Genet 1998;82:147-52.
    • (1998) Cytogenet Cell Genet , vol.82 , pp. 147-152
    • Kimura, M.1    Matsuda, Y.2    Yoshioka, T.3    Sumi, N.4    Okano, Y.5
  • 39
    • 33845743957 scopus 로고    scopus 로고
    • Aurora kinases: New targets for cancer therapy
    • Carvajal RD, Tse A, Schwartz GK. Aurora kinases: new targets for cancer therapy. Clin Cancer Res 2006;12:6869-75.
    • (2006) Clin Cancer Res , vol.12 , pp. 6869-6875
    • Carvajal, R.D.1    Tse, A.2    Schwartz, G.K.3
  • 41
    • 0037105758 scopus 로고    scopus 로고
    • Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability
    • Ota T, Suto S, Katayama H, et al. Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability. Cancer Res 2002;62:5168-77.
    • (2002) Cancer Res , vol.62 , pp. 5168-5177
    • Ota, T.1    Suto, S.2    Katayama, H.3
  • 42
    • 0032213515 scopus 로고    scopus 로고
    • Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells
    • Tatsuka M, Katayama H, Ota T, et al. Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res 1998;58:4811-6.
    • (1998) Cancer Res , vol.58 , pp. 4811-4816
    • Tatsuka, M.1    Katayama, H.2    Ota, T.3
  • 43
    • 0033548619 scopus 로고    scopus 로고
    • Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3
    • Kimura M, Matsuda Y, Yoshioka T, Okano, Y. Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3. J Biol Chem 1999;274:7334-40.
    • (1999) J Biol Chem , vol.274 , pp. 7334-7340
    • Kimura, M.1    Matsuda, Y.2    Yoshioka, T.3    Okano, Y.4
  • 44
    • 33744962325 scopus 로고    scopus 로고
    • Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1
    • Udayakumar TS, Belakavadi M, Choi KH, Pandey PK, Fondell JD. Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1. J Biol Chem 2006;281:14691-9.
    • (2006) J Biol Chem , vol.281 , pp. 14691-14699
    • Udayakumar, T.S.1    Belakavadi, M.2    Choi, K.H.3    Pandey, P.K.4    Fondell, J.D.5
  • 45
    • 0037155870 scopus 로고    scopus 로고
    • Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1
    • Tanaka M, Ueda A, Kanamori H, et al. Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1. J Biol Chem 2002;277:10719-26.
    • (2002) J Biol Chem , vol.277 , pp. 10719-10726
    • Tanaka, M.1    Ueda, A.2    Kanamori, H.3
  • 46
    • 34547109084 scopus 로고    scopus 로고
    • Overexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients
    • Landen CN, Jr., Lin YG, Immaneni A, et al. Overexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients. Clin Cancer Res 2007;13:4098-104.
    • (2007) Clin Cancer Res , vol.13 , pp. 4098-4104
    • Landen Jr., C.N.1    Lin, Y.G.2    Immaneni, A.3
  • 47
    • 34249327737 scopus 로고    scopus 로고
    • Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis
    • Hayama S, Daigo Y, Yamabuki T, et al. Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis. Cancer Res 2007;67:4113-22.
    • (2007) Cancer Res , vol.67 , pp. 4113-4122
    • Hayama, S.1    Daigo, Y.2    Yamabuki, T.3
  • 48
    • 34249791474 scopus 로고    scopus 로고
    • Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians
    • Chen J, Li D, Wei C, et al. Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians. Clin Cancer Res 2007;13:3100-4.
    • (2007) Clin Cancer Res , vol.13 , pp. 3100-3104
    • Chen, J.1    Li, D.2    Wei, C.3
  • 49
    • 0032100685 scopus 로고    scopus 로고
    • A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
    • Bischoff JR, Anderson L, Zhu Y, et al. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 1998;17:3052-65.
    • (1998) EMBO J , vol.17 , pp. 3052-3065
    • Bischoff, J.R.1    Anderson, L.2    Zhu, Y.3
  • 50
    • 23044503962 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells
    • Nozawa S, Ohno T, Banno Y, Dohjima T, Wakahara K, Fan DG, Shimizu K. Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells. J Biol Chem 2005;280:27544-51.
    • (2005) J Biol Chem , vol.280 , pp. 27544-27551
    • Nozawa, S.1    Ohno, T.2    Banno, Y.3    Dohjima, T.4    Wakahara, K.5    Fan, D.G.6    Shimizu, K.7
  • 51
    • 0038489117 scopus 로고    scopus 로고
    • Small interfering RNAs expressed from a Pol III promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line
    • Dohjima T, Lee NS, Li H, Ohno T, Rossi JJ. Small interfering RNAs expressed from a Pol III promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line. Mol Ther 2003;7:811-6.
    • (2003) Mol Ther , vol.7 , pp. 811-816
    • Dohjima, T.1    Lee, N.S.2    Li, H.3    Ohno, T.4    Rossi, J.J.5
  • 52
    • 0033619191 scopus 로고    scopus 로고
    • Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells
    • Thompson AD, Teitell M, Arvand A, Denny CT. Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells. Oncogene 1999;18:5506-13.
    • (1999) Oncogene , vol.18 , pp. 5506-5513
    • Thompson, A.D.1    Teitell, M.2    Arvand, A.3    Denny, C.T.4
  • 53
    • 0242574348 scopus 로고    scopus 로고
    • Homotypic and heterotypic interactions of EWS, FLI1 and their oncogenic fusion protein
    • Spahn L, Siligan C, Bachmaier R, Schmid JA, Aryee DN, Kovar H. Homotypic and heterotypic interactions of EWS, FLI1 and their oncogenic fusion protein. Oncogene 2003;22:6819-29.
    • (2003) Oncogene , vol.22 , pp. 6819-6829
    • Spahn, L.1    Siligan, C.2    Bachmaier, R.3    Schmid, J.A.4    Aryee, D.N.5    Kovar, H.6
  • 54
    • 31544474854 scopus 로고    scopus 로고
    • The possible role of EWS-Fli1 in evasion of senescence in Ewing family tumors
    • Matsunobu T, Tanaka K, Iwamoto Y, et al. The possible role of EWS-Fli1 in evasion of senescence in Ewing family tumors. Cancer Res 2006;66:803-11.
    • (2006) Cancer Res , vol.66 , pp. 803-811
    • Matsunobu, T.1    Tanaka, K.2    Iwamoto, Y.3
  • 55
    • 0034968428 scopus 로고    scopus 로고
    • Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression
    • Dauphinot L, De Oliveira C, Melot T, et al. Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression. Oncogene 2001;20:3258-65.
    • (2001) Oncogene , vol.20 , pp. 3258-3265
    • Dauphinot, L.1    De Oliveira, C.2    Melot, T.3
  • 56
    • 0035834675 scopus 로고    scopus 로고
    • DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis
    • Welford SM, Hebert SP, Deneen B, Arvand A, Denny CT. DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis. J Biol Chem 2001;276:41977-84.
    • (2001) J Biol Chem , vol.276 , pp. 41977-41984
    • Welford, S.M.1    Hebert, S.P.2    Deneen, B.3    Arvand, A.4    Denny, C.T.5
  • 57
    • 0348141703 scopus 로고    scopus 로고
    • Characterization of the A673 cell line (Ewing tumor) by molecular cytogenetic techniques
    • Coleman N, Roberts I. Characterization of the A673 cell line (Ewing tumor) by molecular cytogenetic techniques. Cancer Genet Cytogenet 2004;148:86.
    • (2004) Cancer Genet Cytogenet , vol.148 , pp. 86
    • Coleman, N.1    Roberts, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.