PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis

Oncogene

Volumn 24, Issue 16, 2005, Pages 2715-2722

  Abaan, Ogan D ^a   Levenson, Amy ^a   Khan, Osman ^a   Furth, Priscilla A ^a   Üren, Aykut ^a   Toretsky, Jeffrey A ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

ESFT; Ewing's Sarcoma; EWS FLI1; Phosphatase; PTPL1

Indexed keywords

AGAR; ENZYME INHIBITOR; ETOPOSIDE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE L1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EWS FLII; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CULTURE; CELL STRAIN COS7; CHROMATIN; CHROMOSOME TRANSLOCATION 11; CONTROLLED STUDY; CULTURE MEDIUM; DNA MICROARRAY; EWING SARCOMA; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; METASTASIS; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION; UPREGULATION;

ANIMALS; BONE NEOPLASMS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CLONING, MOLECULAR; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; ONCOGENE PROTEINS, FUSION; PHENOTYPE; PROTEIN BINDING; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEIN C-FLI-1; SARCOMA, EWING'S; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 17844370020     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208247     Document Type: Article

References (49)

1. Baer C, Nees M, Breit S, Selle B, Kulozik AE, Schaefer KL, Braun Y, Wai D and Poremba C. (2004). Int. J. Cancer, 110, 687-694.
2. Banville D, Ahmad S, Stocco R and Shen SH. (1994). J. Biol. Chem., 269, 22320-22327.
3. Bompard G, Martin M, Roy C, Vignon F and Freiss G. (2003). J. Cell Sci., 116, 2519-2530.
4. Bompard G, Puech C, Prebois C, Vignon F and Freiss G. (2002). J. Biol. Chem., 277, 47861-47869.
5. Dauphinot L, De Oliveira C, Melot T, Sevenet N, Thomas V, Weissman BE and Delattre O. (2001). Oncogene, 20, 3258-3265.
6. de Alava E and Gerald WL. (2000). J. Clin. Oncol., 18, 204-213.
7. Deneen B, Hamidi H and Denny CT. (2003a). Cancer Res., 63, 4268-4274.
8. Deneen B, Welford SM, Ho T, Hernandez F, Kurland I and Denny CT. (2003b). Mol. Cell. Biol., 23, 3897-3908.
9. Erdmann K. (2003). Eur. J. Biochem., 270, 4789-4798.
10. Fan C, Li Q, Ross D and Engelhardt JF. (2003). J. Biol. Chem., 278, 2072-2080.
11. Fan C, Yang J and Engelhardt JF. (2002). J. Cell Sci., 115, 4843-4853.
12. Freiss G, Puech C and Vignon F. (1998). Mol. Endocrinol., 12, 568-579.
13. Fukuma M, Okita H, Hata J and Umezawa A. (2003). Oncogene, 22, 1-9.
14. Gil-Henn H and Elson A. (2003). J. Biol. Chem., 278, 15579-15586.
15. Grier HE, Krailo MD, Tarbell NJ, Link MP, Fryer CJ, Pritchard DJ, Gebhardt MC, Dickman PS, Perlman EJ, Meyers PA, Donaldson SS, Moore S, Rausen AR, Vietti TJ and Miser JS. (2003). N. Engl. J. Med, 348, 694-701.
16. Hahm KB, Cho K, Lee C, Im YH, Chang J, Choi SG, Sorensen PH, Thiele CJ and Kim SJ. (1999). Nat. Genet., 23, 222-227.
17. Houghton JA, Harwood FG, Gibson AA and Tillman DM. (1997). Clin. Cancer Res., 3, 2205-2209.
18. Irie S, Li Y, Kanki H, Ohyama T, Deaven LL, Somlo S and Sato TA. (2001). DNA Sequence, 11, 519-526.
19. Ivanov VN, Lopez Bergami P, Maulit G, Sato TA, Sassoon D and Ronai Z. (2003). Mol. Cell. Biol., 23, 3623-3635.
20. Khan J, Wei JS, Ringner M, Saal LH, Ladanyi M, Westermann F, Berthold F, Schwab M, Antonescu CR, Peterson C and Meltzer PS. (2001). Nat. Med., 7, 673-679.
21. Komada Y, Inaba H, Zhou YW, Zhang XL, Tanaka S, Azuma E and Sakurai M. (1997). Br. J. Haematol., 99, 325-330.
22. Kontny HU, Lehrnbecher TM, Chanock SJ and Mackall CL. (1998). Cancer Res., 58, 5842-5849.
23. Kovar H, Aryee DN, Jug G, Henockl C, Schemper M, Delattre O, Thomas G and Gadner H. (1996). Cell Growth Differ., 7, 429-437.
24. Lee SH, Shin MS, Lee JY, Park WS, Kim SY, Jang JJ, Dong SM, Na EY, Kim CS, Kim SH and Yoo NJ. (1999). J. Pathol., 188, 207-212.
25. Lessnick SL, Dacwag CS and Golub TR. (2002). Cancer Cell, 1, 393-401.
26. Maekawa K, Imagawa N, Naito A, Harada S, Yoshie O and Takagi S. (1999). Biochem. J., 337 (Part 2), 179-184.
27. Mao X, Miesfeldt S, Yang H, Leiden JM and Thompson CB. (1994). J. Biol. Chem., 269, 18216-18222.
28. May WA, Gishizky ML, Lessnick SL, Lunsford LB, Lewis BC, Delattre O, Zucman J, Thomas G and Denny CT. (1993). Proc. Natl. Acad. Sci. USA, 90, 5752-5756.
29. Mitsiades N, Poulaki V, Leone A and Tsokos M. (1999). J. Natl. Cancer Inst., 91, 1678-1684.
30. Murthy KK, Clark K, Fortin Y, Shen SH and Banville D. (1999). J. Biol. Chem., 274, 20679-20687.
31. Myc A, Arscott PL, Bretz JD, Thompson NW and Baker Jr JR. (1999). Endocrinology, 140, 5431-5434.
32. Nakai Y, Irie S and Sato TA. (2000). Eur. J. Biochem., 267, 7170-7175.
33. Nakatani F, Tanaka K, Sakimura R, Matsumoto Y, Matsunobu T, Li X, Hanada M, Okada T and Iwamoto Y. (2003). J. Biol. Chem., 278, 15105-15115.
34. Nishimori H, Sasaki Y, Yoshida K, Irifune H, Zembutsu H, Tanaka T, Aoyama T, Hosaka T, Kawaguchi S, Wada T, Hata J, Toguchida J, Nakamura Y and Tokino T. (2002). Oncogene, 21, 8302-8309.
35. Saras J, Claesson-Welsh L, Heldin CH and Gonez LJ. (1994). J. Biol. Chem., 269, 24082-24089.
36. Saras J, Engstrom U, Gonez LJ and Heldin CH. (1997a). J. Biol. Chem., 272, 20979-20981.
37. Saras J, Franzen P, Aspenstrom P, Hellman U, Gonez LJ and Heldin CH. (1997b). J. Biol. Chem., 272, 24333-24338.
38. Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR and Olefsky JM. (1995). J. Biol. Chem., 270, 19151-19157.
39. Tanaka K, Iwakuma T, Harimaya K, Sato H and Iwamoto Y. (1997). J. Clin. Invest., 99, 239-247.
40. Tanaka S, Ito T and Wands JR. (1996). J Biol. Chem., 271, 14610-14616.
41. Thompson AD, Braun BS, Arvand A, Stewart SD, May WA, Chen E, Korenberg J and Denny C. (1996). Oncogene, 13, 2649-2658.
42. Toretsky JA, Kalebic T, Blakesley V, LeRoith D and Helman LJ. (1997). J. Biol. Chem., 272, 30822-30827.
43. Toretsky JA, Thakar M, Eskenazi AE and Frantz CN. (1999). Cancer Res., 59, 5745-5750.
44. Ungefroren H, Voss M, Jansen M, Roeder C, Henne-Bruns D, Kremer B and Kalthoff H. (1998). Cancer Res., 58, 1741-1749.
45. Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C and Toretsky JA. (2003). Oncogene, 22, 2334-2342.
46. Uslu R, Borsellino N, Frost P, Garban H, Ng CP, Mizutani Y, Belldegrun A and Bonavida B. (1997). Clin. Cancer Res., 3, 963-972.
47. Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zembutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y and Tokino T. (2003). Genes Chromosomes Cancer, 36, 224-232.
48. Xiao S, Rose DW, Sasaoka T, Maegawa H, Burke Jr TR, Roller PP, Shoelson SE and Olefsky JM. (1994). J. Biol. Chem., 269, 21244-21248.
49. Zwerner JP and May WA. (2001). Oncogene, 20, 626-633.