EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma

PLoS ONE

Volumn 3, Issue 4, 2008, Pages

  Owen, Leah A ^a   Kowalewski, Ashley A ^a   Lessnick, Stephen L ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HISTONE DEACETYLASE; PROTEIN NKX2.2; RNA BINDING PROTEIN EWS; TRANSCRIPTION FACTOR; EWS FLI FUSION PROTEIN; EWS-FLI FUSION PROTEIN; HOMEODOMAIN PROTEIN; NKX 2.2 HOMEDOMAIN PROTEIN; NKX-2.2 HOMEDOMAIN PROTEIN; ONCOPROTEIN;

ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; EWING SARCOMA; GENE EXPRESSION PROFILING; GENE LOCATION; GENE REPRESSION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MICROARRAY ANALYSIS; PHENOTYPE; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; TRANSCRIPTION INITIATION; ANIMAL; BIOLOGICAL MODEL; CELL TRANSFORMATION; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; MICE; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEINS, FUSION; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; SARCOMA, EWING'S; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 44849085869     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001965     Document Type: Article

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