Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma

Cancer Letters

Volumn 274, Issue 1, 2009, Pages 143-150

  Semba, Shuho ^a   Satake, Shinya ^a   Matsushita, Mai ^a   Yokozaki, Hiroshi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

CDX2; Claudin; Gastric carcinoma; Intestinal differentiation; PTEN

Indexed keywords

CLAUDIN 3; CLAUDIN 4; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR CDX2; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CYTOPLASM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CARCINOMA; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CYTOPLASM; FLUORESCENT ANTIBODY TECHNIQUE; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; INTESTINES; MEMBRANE PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STOMACH NEOPLASMS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 57749084424     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.09.019     Document Type: Article

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