Dehydroepiandrosterone augments sensitivity to γ-ray irradiation in human H4 neuroglioma cells through down-regulation of Akt signaling

Free Radical Research

Volumn 42, Issue 11-12, 2008, Pages 957-965

  Hirao, Tomohito ^a   Urata, Yoshishige ^a   Kageyama, Kan ^a   Ikezaki, Midori ^a   Kawakatsu, Miho ^a   Matsuse, Michiko ^a   Matsuo, Takayuki ^a   Akishita, Masahiro ^b   Nagata, Izumi ^a   Kondo, Takahito ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

glutamylcysteine synthetase; Akt; Dehydroepiandrosterone; Glutathione; Protein phosphatase 2A; Radiation

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PRASTERONE; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GAMMA RADIATION; GLIOMA CELL; GLUTATHIONE METABOLISM; HORMONE RESPONSE; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION INJURY; RADIOSENSITIVITY; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL COUNT; CELL CYCLE; CELL PROLIFERATION; DEHYDROEPIANDROSTERONE; GAMMA RAYS; GAMMA-GLUTAMYLCYCLOTRANSFERASE; GLUTATHIONE; HUMANS; OXIDATION-REDUCTION; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION TOLERANCE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 57649180525     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760802566582     Document Type: Article

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