-
1
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
Geng, L., Donnelly, E., McMahon, G., Lin, P. C., Sierra-Rivera, E., Oshinka, H., and Hallahan, D. E. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res., 61: 2413-2419, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
Lin, P.C.4
Sierra-Rivera, E.5
Oshinka, H.6
Hallahan, D.E.7
-
2
-
-
0037102157
-
Phosphatidylinositol 3-kinase/Akt signaling in the response of vascular endothelium to ionizing radiation
-
Edwards, E., Geng, L., Tan, J., Onishko, H., Donnelly, E., and Hallahan. D. E. Phosphatidylinositol 3-kinase/Akt signaling in the response of vascular endothelium to ionizing radiation. Cancer Res., 62: 4671-4677, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 4671-4677
-
-
Edwards, E.1
Geng, L.2
Tan, J.3
Onishko, H.4
Donnelly, E.5
Hallahan, D.E.6
-
3
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek, H., Datta, S. R., Franke, T. F., Birnbaum, M. J., Yao, R., Cooper, G. M., Segal, R. A., Kaplan, D. R., and Greenberg, M. E. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (Wash. DC), 275: 661-665, 1997.
-
(1997)
Science (Wash. DC)
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
4
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell, 91: 231-241, 1997.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
5
-
-
0034320568
-
Mechanisms of apoptosis
-
Reed, J. C. Mechanisms of apoptosis. Am. J. Pathol., 157: 1415-1430, 2000.
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1415-1430
-
-
Reed, J.C.1
-
6
-
-
0026720350
-
Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit
-
Hiles, I. D., Otsu, M., Volinia, S., Fry, M. J., Gout, I., Dhand, R., Panayotou, G., Ruiz-Larrea, F., Thompson, A., Totty, N. F., et al. Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell, 70: 419-429, 1992.
-
(1992)
Cell
, vol.70
, pp. 419-429
-
-
Hiles, I.D.1
Otsu, M.2
Volinia, S.3
Fry, M.J.4
Gout, I.5
Dhand, R.6
Panayotou, G.7
Ruiz-Larrea, F.8
Thompson, A.9
Totty, N.F.10
-
7
-
-
0027198412
-
A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo
-
Klippel, A., Escobedo, J. A., Hu, Q., and Williams, L. T. A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo. Mol. Cell. Biol., 13: 5560-5566, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 5560-5566
-
-
Klippel, A.1
Escobedo, J.A.2
Hu, Q.3
Williams, L.T.4
-
8
-
-
0028198330
-
The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity
-
Klippel, A., Escobedo, J. A., Hirano, M., and Williams, L. T. The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity. Mol. Cell. Biol., 14: 2675-2685, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2675-2685
-
-
Klippel, A.1
Escobedo, J.A.2
Hirano, M.3
Williams, L.T.4
-
9
-
-
0029009331
-
Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells
-
Sakaue, H., Hara, K., Noguchi, T., Matozaki, T., Kotani, K., Ogawa, W., Yonezawa, K., Waterfield, M. D., and Kasuga, M. Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells. J. Biol. Chem., 270: 11304-11309, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11304-11309
-
-
Sakaue, H.1
Hara, K.2
Noguchi, T.3
Matozaki, T.4
Kotani, K.5
Ogawa, W.6
Yonezawa, K.7
Waterfield, M.D.8
Kasuga, M.9
-
10
-
-
0027981333
-
1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells
-
Hara, K., Yonezawa, K., Sakaue, H., Ando, A., Kotani, K., Kitamura, T., Kitamura, Y., Ueda, H., Stephens, L., Jackson, T. R., et al. 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc. Natl. Acad. Sci. USA, 91: 7415-7419, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7415-7419
-
-
Hara, K.1
Yonezawa, K.2
Sakaue, H.3
Ando, A.4
Kotani, K.5
Kitamura, T.6
Kitamura, Y.7
Ueda, H.8
Stephens, L.9
Jackson, T.R.10
-
11
-
-
0033597752
-
Dominant negative forms of Akt (protein kinase B) and atypical protein kinase C λ do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription
-
Kotani, K., Ogawa, W., Hino, Y., Kitamura, T., Ueno, H., Sano, W., Sutherland, C., Granner, D. K., and Kasuga, M. Dominant negative forms of Akt (protein kinase B) and atypical protein kinase C λ do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription. J. Biol. Chem., 274: 21305-21312, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21305-21312
-
-
Kotani, K.1
Ogawa, W.2
Hino, Y.3
Kitamura, T.4
Ueno, H.5
Sano, W.6
Sutherland, C.7
Granner, D.K.8
Kasuga, M.9
-
12
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
Paris, F., Fuks, Z., Kang, A., Capodieci, P., Juan, G., Ehleiter, D., Haimovitz-Friedman, A., Cordon-Cardo, C., and Kolesnick, R. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science (Wash. DC), 293: 293-297, 2001.
-
(2001)
Science (Wash. DC)
, vol.293
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
Capodieci, P.4
Juan, G.5
Ehleiter, D.6
Haimovitz-Friedman, A.7
Cordon-Cardo, C.8
Kolesnick, R.9
-
13
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Wash. DC), 281: 1309-1312, 1998.
-
(1998)
Science (Wash. DC)
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
14
-
-
0031870774
-
Apoptosis: Molecular aspects of cell death and disease
-
Granville, D. J., Carthy, C. M., Hunt, D. W., and McManus, B. M. Apoptosis: molecular aspects of cell death and disease. Lab. Investig., 78: 893-913, 1998.
-
(1998)
Lab. Investig.
, vol.78
, pp. 893-913
-
-
Granville, D.J.1
Carthy, C.M.2
Hunt, D.W.3
McManus, B.M.4
-
15
-
-
0038281227
-
Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002
-
Gupta, A. K., Cerniglia, G. J., Mick, R., Ahmed, M. S., Bakanauskas, V. J., Muschel, R. J., and McKenna, W. G. Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002. Int. J. Radiat. Oncol. Biol. Phys., 56: 846-853, 2003.
-
(2003)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.56
, pp. 846-853
-
-
Gupta, A.K.1
Cerniglia, G.J.2
Mick, R.3
Ahmed, M.S.4
Bakanauskas, V.J.5
Muschel, R.J.6
McKenna, W.G.7
-
16
-
-
0036304685
-
Local recurrence in head and neck cancer: Relationship to radiation resistance and signal transduction
-
Gupta, A. K., McKenna, W. G., Weber, C. N., Feldman, M. D., Goldsmith, J. D., Mick, R., Machtay, M., Rosenthal, D. I., Bakanauskas, V. J., Cemiglia, G. J., Bemhard, E. J., Weber, R. S., and Muschel, R. J. Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin. Cancer Res., 8: 885-892, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 885-892
-
-
Gupta, A.K.1
McKenna, W.G.2
Weber, C.N.3
Feldman, M.D.4
Goldsmith, J.D.5
Mick, R.6
Machtay, M.7
Rosenthal, D.I.8
Bakanauskas, V.J.9
Cemiglia, G.J.10
Bemhard, E.J.11
Weber, R.S.12
Muschel, R.J.13
-
17
-
-
0042399368
-
Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy
-
Liang, K., Jin, W., Knuefermann, C., Schmidt, M., Mills, G. B., Ang, K. K., Milas, L., and Fan, Z. Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy. Mol. Cancer Ther., 2: 353-360, 2003.
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 353-360
-
-
Liang, K.1
Jin, W.2
Knuefermann, C.3
Schmidt, M.4
Mills, G.B.5
Ang, K.K.6
Milas, L.7
Fan, Z.8
-
18
-
-
0037069932
-
In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways
-
Kraus, A. C., Ferber, I., Bachmann, S. O., Specht, H., Wimmel, A., Gross, M. W., Schlegel, J., Suske, G., and Schuermann, M. In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways. Oncogene, 21: 8683-8695, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 8683-8695
-
-
Kraus, A.C.1
Ferber, I.2
Bachmann, S.O.3
Specht, H.4
Wimmel, A.5
Gross, M.W.6
Schlegel, J.7
Suske, G.8
Schuermann, M.9
-
19
-
-
0033628571
-
Phosphatidylinositol-3 kinase dependent pathways: The role in control of cell growth, survival, and malignant transformation
-
Krasilnikov, M. A. Phosphatidylinositol-3 kinase dependent pathways: the role in control of cell growth, survival, and malignant transformation. Biochemistry, 65: 59-67, 2000.
-
(2000)
Biochemistry
, vol.65
, pp. 59-67
-
-
Krasilnikov, M.A.1
-
20
-
-
18644376568
-
Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage
-
Deverman, B. E., Cook, B. L., Manson, S. R., Niederhoff, R. A., Langer, E. M., Rosova, I., Kulans, L. A., Fu, X., Weinberg, J. S., Heinecke, J. W., Roth, K. A., and Weintraub, S. J. Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. Cell, 111: 51-62, 2002.
-
(2002)
Cell
, vol.111
, pp. 51-62
-
-
Deverman, B.E.1
Cook, B.L.2
Manson, S.R.3
Niederhoff, R.A.4
Langer, E.M.5
Rosova, I.6
Kulans, L.A.7
Fu, X.8
Weinberg, J.S.9
Heinecke, J.W.10
Roth, K.A.11
Weintraub, S.J.12
-
21
-
-
0032806132
-
Ionizing radiation-induced Bax-mediated cell death is dependent on activation of cysteine and serine proteases
-
Gong, B., Chen, Q., Endlich, B., Mazumder, S., and Almasan, A. Ionizing radiation-induced Bax-mediated cell death is dependent on activation of cysteine and serine proteases. Cell Growth Differ., 10: 491-502, 1999.
-
(1999)
Cell Growth Differ.
, vol.10
, pp. 491-502
-
-
Gong, B.1
Chen, Q.2
Endlich, B.3
Mazumder, S.4
Almasan, A.5
-
22
-
-
0037017396
-
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
-
Dijkers, P. F., Birkenkamp, K. U., Lam, E. W., Thomas, N. S., Lammers, J. W., Koenderman, L., and Coffer, P. J. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J. Cell Biol., 156: 531-542, 2002.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 531-542
-
-
Dijkers, P.F.1
Birkenkamp, K.U.2
Lam, E.W.3
Thomas, N.S.4
Lammers, J.W.5
Koenderman, L.6
Coffer, P.J.7
-
23
-
-
0035843140
-
Irradiation of mitochondria initiates apoptosis in a cell free system
-
Taneja, N., Tjalkens, R., Philbert, M. A., and Rehemtulla, A. Irradiation of mitochondria initiates apoptosis in a cell free system. Oncogene, 20: 167-177, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 167-177
-
-
Taneja, N.1
Tjalkens, R.2
Philbert, M.A.3
Rehemtulla, A.4
-
24
-
-
0036889475
-
Oxygen deprivation induced cell death: An update
-
Brunelle, J. K., and Chandel, N. S. Oxygen deprivation induced cell death: an update. Apoptosis, 7: 475-482, 2002.
-
(2002)
Apoptosis
, vol.7
, pp. 475-482
-
-
Brunelle, J.K.1
Chandel, N.S.2
|