Rationally designed anti-HIV peptides containing multifunctional domains as molecule probes for studying the mechanisms of action of the first and second generation HIV fusion inhibitors

Journal of Biological Chemistry

Volumn 283, Issue 44, 2008, Pages 30376-30384

  Qi, Zhi ^a   Shi, Weiguo ^b   Xue, Na ^a   Pan, Chungen ^a,c   Jing, Weiguo ^a   Liu, Keliang ^b   Jiang, Shibo ^a  

^a NEW YORK BLOOD CENTER   (United States)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; DRUG PRODUCTS; FLOW INTERACTIONS; LUTETIUM; MACHINE DESIGN; PEPTIDES; PORT TERMINALS; PROTEINS; VIRUSES;

A STABLES; BINDING DOMAINS; BIOPHYSICAL PROPERTIES; CELL FUSIONS; CORE FORMATIONS; FIRST GENERATIONS; FUSION INHIBITORS; FUSION PROTEINS; HELIX BUNDLES; HIV FUSION INHIBITORS; HUMAN IMMUNODEFICIENCY VIRUSES; INHIBITORY ACTIVITIES; MOLECULE PROBES; MULTIFUNCTIONAL DOMAINS; RATIONAL DESIGNS; SECOND GENERATIONS; STRUCTURE DOMAINS; TARGET SITES;

BUDGET CONTROL;

C 34; ENFUVIRTIDE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; T 1249; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; COMPARATIVE STUDY; DRUG DESIGN; DRUG MECHANISM; LIPID VESICLE; MOLECULAR PROBE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CIRCULAR DICHROISM; DRUG DESIGN; HIV INFECTIONS; HUMANS; LIPID BILAYERS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 57649155175     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804672200     Document Type: Article

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