-
1
-
-
0242529051
-
Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral naive patients
-
I.CO.N.A. Study Group. Italian Cohort of Antiretroviral-Naive Patients
-
D'ARMINIO MONFORTE A, LEPRI AC, REZZA G et al.: Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral naive patients. I.CO.N.A. Study Group. Italian Cohort of Antiretroviral-Naive Patients. AIDS (2000) 14(5):499-507.
-
(2000)
AIDS
, vol.14
, Issue.5
, pp. 499-507
-
-
D'arminio Monforte, A.1
Lepri, A.C.2
Rezza, G.3
-
2
-
-
0033587510
-
Highly active antiretroviral therapy in a large urban clinic: Risk factors for virologic failure and adverse drug reactions
-
LUCAS GM, CHAISSON RE, MOORE RD: Highly active antiretroviral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions. Ann. Intern. Med. (1999) 131 (2):81-87.
-
(1999)
Ann. Intern. Med.
, vol.131
, Issue.2
, pp. 81-87
-
-
Lucas, G.M.1
Chaisson, R.E.2
Moore, R.D.3
-
3
-
-
0032103187
-
Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients
-
SHAFER RW, WINTERS MA, PALMER S, MERIGAN TC: Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients. Ann. Intern. Med. (1998) 128(11):906-911.
-
(1998)
Ann. Intern. Med.
, vol.128
, Issue.11
, pp. 906-911
-
-
Shafer, R.W.1
Winters, M.A.2
Palmer, S.3
Merigan, T.C.4
-
4
-
-
16644381659
-
The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection
-
MAEDA K, NAKATA H, OGATA H et al.: The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection. Curr. Opin. Pharmacol. (2004) 4 5):447-452.
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, Issue.5
, pp. 447-452
-
-
Maeda, K.1
Nakata, H.2
Ogata, H.3
-
5
-
-
4544381403
-
HIV fusion and its inhibition in antiretroviral therapy
-
GREENBERG M, CAMMACK N, SALGO M, SMILEY L: HIV fusion and its inhibition in antiretroviral therapy. Rev. Med. Virol. (2004) 14 5):321-337.
-
(2004)
Rev. Med. Virol.
, vol.14
, Issue.5
, pp. 321-337
-
-
Greenberg, M.1
Cammack, N.2
Salgo, M.3
Smiley, L.4
-
7
-
-
3042595910
-
Small-molecule antagonists of CCR5 and CXCR4: A promising new class of anti-HIV-1 drugs
-
SEIBERT C, SAKMAR TP: Small-molecule antagonists of CCR5 and CXCR4: a promising new class of anti-HIV-1 drugs. Curr. Pharm. Des (2004) 10(17):2041-2062.
-
(2004)
Curr. Pharm. Des.
, vol.10
, Issue.17
, pp. 2041-2062
-
-
Seibert, C.1
Sakmar, T.P.2
-
8
-
-
0032577550
-
HIV entry and its inhibition
-
CHAN DC, KIM PS: HIV entry and its inhibition. Cell (1998) 93(5):681-684.
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 681-684
-
-
Chan, D.C.1
Kim, P.S.2
-
9
-
-
0032902197
-
Structural basis for membrane fusion by enveloped viruses
-
WEISSENHORN W, DESSEN A, CALDER LJ et al.: Structural basis for membrane fusion by enveloped viruses. Mol. Membr. Biol. (1999) 16(1):3-9.
-
(1999)
Mol. Membr. Biol.
, vol.16
, Issue.1
, pp. 3-9
-
-
Weissenhorn, W.1
Dessen, A.2
Calder, L.J.3
-
10
-
-
0038576281
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
LALEZARI JP, HENRY K, O'HEARN M et al.: Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N. Engl. Med. (2003) 348(22):2175-2185.
-
(2003)
N. Engl. Med.
, vol.348
, Issue.22
, pp. 2175-2185
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
-
11
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
-
LAZZARIN A, CLOTET B, COOPER DA et al.: Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. N. Engl. J. Med. (2003) 348(22):2186-2195.
-
(2003)
N. Engl. J. Med.
, vol.348
, Issue.22
, pp. 2186-2195
-
-
Lazzarin, A.1
Clotet, B.2
Cooper, D.A.3
-
12
-
-
1642391068
-
Enfuvirtide: The first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes
-
MATTHEWS T, SALGO M, GREENBERG M et al.: Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes. Nat. Rev. Drug Discov. (2004) 3(3):215-225.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, Issue.3
, pp. 215-225
-
-
Matthews, T.1
Salgo, M.2
Greenberg, M.3
-
13
-
-
0027959493
-
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus Type 1 gp41 are potent inhibitors of virus infection
-
WILD CT, SHUGARS DC, GREENWELL TK, MCDANAL CB, MATTHEWS TJ: Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus Type 1 gp41 are potent inhibitors of virus infection. Proc. Natl. Acad. Sci. USA (1994) 91 21):9770-9774.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, Issue.21
, pp. 9770-9774
-
-
Wild, C.T.1
Shugars, D.C.2
Greenwell, T.K.3
McDanal, C.B.4
Matthews, T.J.5
-
14
-
-
0032433685
-
Evidence that a prominent cavity in the coiled coil of HIV Type 1 gp41 is an attractive drug target
-
CHAN DC, CHUTKOWSKI CT, KIM PS: Evidence that a prominent cavity in the coiled coil of HIV Type 1 gp41 is an attractive drug target. Proc. Natl. Acad. Sci. USA (1998) 95(26):15613-15617.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.26
, pp. 15613-15617
-
-
Chan, D.C.1
Chutkowski, C.T.2
Kim, P.S.3
-
15
-
-
0034645796
-
Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation
-
KLIGER Y, SHAI Y: Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation. J. Mol. Biol. (2000) 295 2):163-168.
-
(2000)
J. Mol. Biol.
, vol.295
, Issue.2
, pp. 163-168
-
-
Kliger, Y.1
Shai, Y.2
-
16
-
-
0031962175
-
Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors
-
JONES PL, KORTE T, BLUMENTHAL R: Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors. J. Biol. Chem. (1998) 273(1):404-409.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.1
, pp. 404-409
-
-
Jones, P.L.1
Korte, T.2
Blumenthal, R.3
-
17
-
-
0038065763
-
Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41
-
MUNOZ-BARROSO I, DURELL S, SAKAGUCHI K, APPELLA E, BLUMENTHAL R: Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41. J. Cell Biol. (1998) 140(2):315-323.
-
(1998)
J. Cell Biol.
, vol.140
, Issue.2
, pp. 315-323
-
-
Munoz-Barroso, I.1
Durell, S.2
Sakaguchi, K.3
Appella, E.4
Blumenthal, R.5
-
18
-
-
0035846960
-
Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage
-
KLIGER Y, GALLO SA, PEISAJOVICH SG et al.: Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage. J. Biol. Chem. (2001) 276(2):1391-1397.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.2
, pp. 1391-1397
-
-
Kliger, Y.1
Gallo, S.A.2
Peisajovich, S.G.3
-
19
-
-
0029926552
-
HIV-1 membrane fusion mechanism: Structural studies of the interactions between biologically-active peptides from gp41
-
LAWLESS MK, BARNEY S, GUTHRIE KI et al.: HIV-1 membrane fusion mechanism: structural studies of the interactions between biologically-active peptides from gp41. Biochemistry (1996) 35 42):13697-13708.
-
(1996)
Biochemistry
, vol.35
, Issue.42
, pp. 13697-13708
-
-
Lawless, M.K.1
Barney, S.2
Guthrie, K.I.3
-
20
-
-
0035313589
-
Human immunodeficiency virus Type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion
-
NAGASHIMA KA, THOMPSON DA, ROSENFIELD SI et al.: Human immunodeficiency virus Type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion. J. Infect. Dis. (2001) 183(7):1121-1125.
-
(2001)
J. Infect. Dis.
, vol.183
, Issue.7
, pp. 1121-1125
-
-
Nagashima, K.A.1
Thompson, D.A.2
Rosenfield, S.I.3
-
21
-
-
0031869099
-
A semiautomated fluorescence-based cell-to-cell fusion assay for gp120-gp41 and CD4 expressing cells
-
PINE PS, WEAVER JL, ORAVECZ T et al.: A semiautomated fluorescence-based cell-to-cell fusion assay for gp120-gp41 and CD4 expressing cells. Exp. Cell Res. (1998) 240(1):49-57.
-
(1998)
Exp. Cell Res.
, vol.240
, Issue.1
, pp. 49-57
-
-
Pine, P.S.1
Weaver, J.L.2
Oravecz, T.3
-
22
-
-
0012823617
-
Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 to 24 weks
-
Boston, MA, USA February Abstract 141
-
GREENBERG ML, MELBY T, SISTA P, et al.: Baseline and on-treatment susceptibility to enfuvirtide seen in TORO 1 and TORO 2 to 24 weks. 10th Conference on Retroviruses and Opportunistic Infections Boston, MA, USA February (2003) Abstract 141.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Greenberg, M.L.1
Melby, T.2
Sista, P.3
-
23
-
-
0033856458
-
Sensitivity of human immunodeficiency virus Type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
-
DERDEYN CA, DECKER JM, SFAKIANOS JN et al.: Sensitivity of human immunodeficiency virus Type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J. Virol. (2000) 74(18):8358-8367.
-
(2000)
J. Virol.
, vol.74
, Issue.18
, pp. 8358-8367
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
24
-
-
0034890660
-
Sensitivity of human immunodeficiency virus Type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
-
DERDEYN CA, DECKER JM, SFAKIANOS JN et al.: Sensitivity of human immunodeficiency virus Type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J. Virol. (2001) 75(18):8605-8614.
-
(2001)
J. Virol.
, vol.75
, Issue.18
, pp. 8605-8614
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
-
25
-
-
0037223692
-
Baseline susceptibility of primary human immunodeficiency virus Type 1 to entry inhibitors
-
LABROSSE B, LABERNARDIERE JL, DAM E et al.: Baseline susceptibility of primary human immunodeficiency virus Type 1 to entry inhibitors. J. Virol. (2003) 77(2):1610-1613.
-
(2003)
J. Virol.
, vol.77
, Issue.2
, pp. 1610-1613
-
-
Labrosse, B.1
Labernardiere, J.L.2
Dam, E.3
-
26
-
-
0042895999
-
Analysis of baseline enfuvirtide (T20) susceptibility and co-receptor tropism in two Phase III study populations
-
Boston, MA, USA Abstract
-
WHITCOMB JM, HUANG W, FRANSEN S, et al.: Analysis of baseline enfuvirtide (T20) susceptibility and co-receptor tropism in two Phase III study populations. 10th Conference on Retroviruses and Opportunistic Infections. Boston, MA, USA (2003) Abstract.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Whitcomb, J.M.1
Huang, W.2
Fransen, S.3
-
27
-
-
0347717476
-
The fusion inhibitors T-20 and T-1249 demonstrate potent in vitro antiviral activity against clade-B HIV-1 isolates resistance to reverse transcriptase and protease inhibitors and non-B clades
-
SISTA P, MELBY T, DHINGRA U, et al.: The fusion inhibitors T-20 and T-1249 demonstrate potent in vitro antiviral activity against clade-B HIV-1 isolates resistance to reverse transcriptase and protease inhibitors and non-B clades. Antivir. Ther. (2001) 6(Suppl. 1):3-4.
-
(2001)
Antivir. Ther.
, vol.6
, Issue.SUPPL. 1
, pp. 3-4
-
-
Sista, P.1
Melby, T.2
Dhingra, U.3
-
29
-
-
1842502574
-
Are fusion inhibitors active against all HIV variants?
-
POVEDA E, RODES B, TORO C, SORIANO V: Are fusion inhibitors active against all HIV variants? AIDS Res. Hum. Retroviruses (2004) 20(3):347-348.
-
(2004)
AIDS Res. Hum. Retroviruses
, vol.20
, Issue.3
, pp. 347-348
-
-
Poveda, E.1
Rodes, B.2
Toro, C.3
Soriano, V.4
-
30
-
-
3042606321
-
Peptide inhibitors of virus-cell fusion: Enfuvirtide as a case study in clinical discovery and development
-
COOPER DA, LANGE JM: Peptide inhibitors of virus-cell fusion: enfuvirtide as a case study in clinical discovery and development. Lancet Infect Dis. (2004) 4(7):426-436.
-
(2004)
Lancet Infect. Dis.
, vol.4
, Issue.7
, pp. 426-436
-
-
Cooper, D.A.1
Lange, J.M.2
-
31
-
-
4444375658
-
Resistance to enfuvirtide, the first HIV fusion inhibitor
-
GREENBERG ML, CAMMACK N: Resistance to enfuvirtide, the first HIV fusion inhibitor. J. Antimicrob. Chemother. (2004) 54 2):333-340.
-
(2004)
J. Antimicrob. Chemother.
, vol.54
, Issue.2
, pp. 333-340
-
-
Greenberg, M.L.1
Cammack, N.2
-
32
-
-
0035805185
-
Primary genotypic resistance of HIV-1 to the fusion inhibitor T-20 in long-term infected patients
-
ZOLLNER B, FEUCHT HH, SCHROTER M et al.: Primary genotypic resistance of HIV-1 to the fusion inhibitor T-20 in long-term infected patients. AIDS (2001) 15(7):935-936.
-
(2001)
AIDS
, vol.15
, Issue.7
, pp. 935-936
-
-
Zollner, B.1
Feucht, H.H.2
Schroter, M.3
-
33
-
-
0031883832
-
Determinants of human immunodeficiency virus Type 1 resistance to gp41-derived inhibitory peptides
-
RIMSKY LT, SHUGARS DC, MATTHEWS TJ: Determinants of human immunodeficiency virus Type 1 resistance to gp41-derived inhibitory peptides. J. Virol. (1998) 72(2):986-993.
-
(1998)
J. Virol.
, vol.72
, Issue.2
, pp. 986-993
-
-
Rimsky, L.T.1
Shugars, D.C.2
Matthews, T.J.3
-
34
-
-
0036090585
-
Emergence of resistant human immunodeficiency virus Type 1 in patients receiving fusion inhibitor (T-20) monotherapy
-
WEI X, DECKER JM, LIU H et al.: Emergence of resistant human immunodeficiency virus Type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob. Agents Chemother. (2002) 46(6):1896-1905.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, Issue.6
, pp. 1896-1905
-
-
Wei, X.1
Decker, J.M.2
Liu, H.3
-
35
-
-
0038069784
-
Impact of HIV-1 gp41 amino acid substitutions (positions 36-45) on susceptibility to T-20 (enfuvirtide) in vitro: Analysis of primary virus isolates receovered from patients during chronic enfuvirtide treatment and site directed mutants in NL4-3
-
MINK M, GREENBERG ML, MOSIER S et al.: Impact of HIV-1 gp41 amino acid substitutions (positions 36-45) on susceptibility to T-20 (enfuvirtide) in vitro: analysis of primary virus isolates receovered from patients during chronic enfuvirtide treatment and site directed mutants in NL4-3. Antivir. Ther. (2002) 7(Suppl. 1):S24.
-
(2002)
Antivir. Ther.
, vol.7
, Issue.SUPPL. 1
-
-
Mink, M.1
Greenberg, M.L.2
Mosier, S.3
-
37
-
-
3042799046
-
Relative replicative fitness of human immunodeficiency virus Type 1 mutants resistant to enfuvirtide (T-20)
-
LU J, SISTA P, GIGUEL F, GREENBERG M, KURITZKES DR: Relative replicative fitness of human immunodeficiency virus Type 1 mutants resistant to enfuvirtide (T-20). J. Virol. (2004) 78 9):4628-4637.
-
(2004)
J. Virol.
, vol.78
, Issue.9
, pp. 4628-4637
-
-
Lu, J.1
Sista, P.2
Giguel, F.3
Greenberg, M.4
Kuritzkes, D.R.5
-
38
-
-
7644236011
-
Emergence of a drug-dependent human immunodeficiency virus Type 1 variant during therapy with the T20 fusion inhibitor
-
BALDWIN CE, SANDERS RW, DENG Y et al.: Emergence of a drug-dependent human immunodeficiency virus Type 1 variant during therapy with the T20 fusion inhibitor. J. Virol. (2004) 78 22):12428-12437.
-
(2004)
J. Virol.
, vol.78
, Issue.22
, pp. 12428-12437
-
-
Baldwin, C.E.1
Sanders, R.W.2
Deng, Y.3
-
39
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
-
KILBY JM, HOPKINS S, VENETTA TM et al.: Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat. Med. (1998) 4 11):1302-1307.
-
(1998)
Nat. Med.
, vol.4
, Issue.11
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, T.M.3
-
40
-
-
0036066762
-
The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults
-
KILBY JM, LALEZARI JP, ERON JJ et al.: The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults. AIDS Res. Hum. Retroviruses (2002) 18 10):685-693.
-
(2002)
AIDS Res. Hum. Retroviruses
, vol.18
, Issue.10
, pp. 685-693
-
-
Kilby, J.M.1
Lalezari, J.P.2
Eron, J.J.3
-
41
-
-
2342614844
-
Safety, tolerability, and plasma pharmacokinetics of high-strength formulations of enfuvirtide (T-20) in treatment-experienced HIV-1-infected parients
-
WHEELER DA, LALEZARI JP, KILBY JM et al.: Safety, tolerability, and plasma pharmacokinetics of high-strength formulations of enfuvirtide (T-20) in treatment-experienced HIV-1-infected parients. J. Clin. Virol. (2004) 30(2):183-190.
-
(2004)
J. Clin. Virol.
, vol.30
, Issue.2
, pp. 183-190
-
-
Wheeler, D.A.1
Lalezari, J.P.2
Kilby, J.M.3
-
42
-
-
0036335809
-
Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition
-
ZHANG X, NIEFORTH K, LANG JM et al.: Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition. Clin. Pharmacol. Ther. (2002) 72 1):10-19.
-
(2002)
Clin. Pharmacol. Ther.
, vol.72
, Issue.1
, pp. 10-19
-
-
Zhang, X.1
Nieforth, K.2
Lang, J.M.3
-
43
-
-
1642292791
-
Enfuvirtide pharmacokinetic-pharmacodynamic (PK-PD) relationship
-
Warsaw, Poland Abstract 4.1/4
-
ZHANG X, BUSS N, SALGO M, PATEL IH: Enfuvirtide pharmacokinetic-pharmacodynamic (PK-PD) relationship. 9th European AIDS Conference. Warsaw, Poland (2003). Abstract 4.1/4.
-
(2003)
9th European AIDS Conference
-
-
Zhang, X.1
Buss, N.2
Salgo, M.3
Patel, I.H.4
-
44
-
-
17144405887
-
Pharmacokinetic (PK), pharmacodynamic, and safety assessment of qd versus bid dosing with enfuvirtide in HIV infected subjects
-
Washington DC, USA, October 30 - November 2 Poster H-866
-
THOMPSON M, TRUE A, CHIU YY et al. Pharmacokinetic (PK), pharmacodynamic, and safety assessment of qd versus bid dosing with enfuvirtide in HIV infected subjects. 44th Interscience Conference on Antimicrob. Agents Chemother Washington DC, USA, October 30 - November 2 (2004). Poster H-866.
-
(2004)
44th Interscience Conference on Antimicrob. Agents Chemother.
-
-
Thompson, M.1
True, A.2
Chiu, Y.Y.3
-
45
-
-
0042885473
-
Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients
-
LALEZARI JP, PATEL IH, ZHANG X et al.: Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients. J. Clin. Virol. (2003) 28(2):217-222.
-
(2003)
J. Clin. Virol.
, vol.28
, Issue.2
, pp. 217-222
-
-
Lalezari, J.P.1
Patel, I.H.2
Zhang, X.3
-
46
-
-
17144383061
-
-
Roche Pharmaceuticals: FUZEON© US Product Information, Roche Pharmaceuticals
-
Roche Pharmaceuticals: FUZEON© US Product Information, Roche Pharmaceuticals (2003).
-
(2003)
-
-
-
47
-
-
11244271641
-
Pharmacokinetics of enfuvirtide in a patient with impaired renal function
-
LEEN C, WAT C, NIEFORTH K: Pharmacokinetics of enfuvirtide in a patient with impaired renal function. Clin. Infect. Dis. (2004) 39(11):e119-e121.
-
(2004)
Clin. Infect. Dis.
, vol.39
, Issue.11
-
-
Leen, C.1
Wat, C.2
Nieforth, K.3
-
48
-
-
0346339863
-
Pharmacokinetics of enfuvirtide in pediatric HIV infected patients receiving combination therapy
-
BELLIBAS SE, SIDDIQUE Z, DORR A, et al.: Pharmacokinetics of enfuvirtide in pediatric HIV infected patients receiving combination therapy. Antivir. Ther. (2003) 8(Suppl. 1):S421.
-
(2003)
Antivir. Ther.
, vol.8
, Issue.SUPPL. 1
-
-
Bellibas, S.E.1
Siddique, Z.2
Dorr, A.3
-
49
-
-
4744362280
-
Enfuvirtide prescription at the end of pregnancy to a multi-treated HIV-infected woman with virological breakthrough
-
MEYOHAS MC, LACOMBE K, CARBONNE B, MORAND-JOUBERT L, GIRARD PM: Enfuvirtide prescription at the end of pregnancy to a multi-treated HIV-infected woman with virological breakthrough. AIDS (2004) 18 14):1966-1968.
-
(2004)
AIDS
, vol.18
, Issue.14
, pp. 1966-1968
-
-
Meyohas, M.C.1
Lacombe, K.2
Carbonne, B.3
Morand-Joubert, L.4
Girard, P.M.5
-
50
-
-
2942594069
-
Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus Type 1-infected patients
-
ZHANG X, LALEZARI JP, BADLEY AD et al.: Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus Type 1-infected patients. Clin. Pharm. Ther. (2004) 75 6):558-568.
-
(2004)
Clin. Pharm. Ther.
, vol.75
, Issue.6
, pp. 558-568
-
-
Zhang, X.1
Lalezari, J.P.2
Badley, A.D.3
-
51
-
-
0242469076
-
Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide
-
BOYD MA, ZHANG X, DORR A et al.: Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide. J. Clin. Pharmacol. (2003) 43(12):1382-1391.
-
(2003)
J. Clin. Pharmacol.
, vol.43
, Issue.12
, pp. 1382-1391
-
-
Boyd, M.A.1
Zhang, X.2
Dorr, A.3
-
52
-
-
2942642589
-
Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1 infected patients
-
RUXRUNGTHAM K, BOYD M, BELLIBAS SE et al.: Lack of interaction between enfuvirtide and ritonavir or ritonavir-boosted saquinavir in HIV-1 infected patients. J. Clin. Pharmacol. (2004) 44(7):793-803.
-
(2004)
J. Clin. Pharmacol.
, vol.44
, Issue.7
, pp. 793-803
-
-
Ruxrungtham, K.1
Boyd, M.2
Bellibas, S.E.3
-
53
-
-
0037471311
-
A Phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy
-
LALEZARI JP, ERON JJ, CARLSON M et al.: A Phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy. AIDS (2003) 17 5):691-698.
-
(2003)
AIDS
, vol.17
, Issue.5
, pp. 691-698
-
-
Lalezari, J.P.1
Eron, J.J.2
Carlson, M.3
-
54
-
-
0032839921
-
Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: Phenotypic resistance to protease inhibitors predicts outcome of therapy
-
PIKETTY C, RACE E, CASTIEL P et al.: Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: phenotypic resistance to protease inhibitors predicts outcome of therapy. AIDS (1999) 13(11):F71-F77.
-
(1999)
AIDS
, vol.13
, Issue.11
-
-
Piketty, C.1
Race, E.2
Castiel, P.3
-
55
-
-
10744229122
-
A controlled Phase II trial assessing three doses of enfuvirtide (T-20) in combination with abacavir, amprenavir, ritonavir and efavirenz in non-nucleoside reverse transcriptase inhibitor-naive HIV-infected adults
-
LALEZARI JP, DEJESUS E, NORTHFELT DW et al.: A controlled Phase II trial assessing three doses of enfuvirtide (T-20) in combination with abacavir, amprenavir, ritonavir and efavirenz in non-nucleoside reverse transcriptase inhibitor-naive HIV-infected adults. Antivir. Ther. (2003) 8(4):279-287.
-
(2003)
Antivir. Ther.
, vol.8
, Issue.4
, pp. 279-287
-
-
Lalezari, J.P.1
DeJesus, E.2
Northfelt, D.W.3
-
56
-
-
4043094071
-
Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children
-
CHURCH JA, HUGHES M, CHEN J et al.: Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children. Pediatr. Infect. Dis. J. (2004) 23 8):713-718.
-
(2004)
Pediatr. Infect. Dis. J.
, vol.23
, Issue.8
, pp. 713-718
-
-
Church, J.A.1
Hughes, M.2
Chen, J.3
-
57
-
-
0036020193
-
Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children
-
CHURCH JA, CUNNINGHAM C, HUGHES M et al.: Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children. Pediatr. Infect. Dis. J. (2002) 21(7):653-659.
-
(2002)
Pediatr. Infect. Dis. J.
, vol.21
, Issue.7
, pp. 653-659
-
-
Church, J.A.1
Cunningham, C.2
Hughes, M.3
-
58
-
-
2642553329
-
24-week safety and efficacy of enfuvirtide as part of an optimized regimen in adolescents
-
San Fransisco, CA, USA Abstract 929
-
WIZNIA A, CHURCH J, STAVOLA J, et al.: 24-week safety and efficacy of enfuvirtide as part of an optimized regimen in adolescents. 11th Conference on Retroviruses and Opportunistic Infections. San Fransisco, CA, USA (2004). Abstract 929.
-
(2004)
11th Conference on Retroviruses and Opportunistic Infections
-
-
Wiznia, A.1
Church, J.2
Stavola, J.3
-
59
-
-
4544386796
-
Enfuvirtide TORO studies: 48 week results confirm 24 week findings
-
Paris, France Abstract LB2
-
KATLAMA C, ARASTÉH K, CLOTET B et al.: Enfuvirtide TORO studies: 48 week results confirm 24 week findings. 2nd International AIDS Society Meeting. Paris, France (2003). Abstract LB2.
-
(2003)
2nd International AIDS Society Meeting
-
-
Katlama, C.1
Arastéh, K.2
Clotet, B.3
-
60
-
-
1642310750
-
Durability of response to enfuvirtide through 48 weeks in the TORO trials
-
Chicago, IL, USA Abstract H-835
-
TROTTIER B, ARASTEH K, HENRY K, et al.: Durability of response to enfuvirtide through 48 weeks in the TORO trials. 43rd Interscience Conference on Antimicrob. Agents Chemother. Chicago, IL, USA (2003). Abstract H-835.
-
(2003)
43rd Interscience Conference on Antimicrob. Agents Chemother.
-
-
Trottier, B.1
Arasteh, K.2
Henry, K.3
-
61
-
-
17144417071
-
TORO: 96 week virological and immunological response and safety evaluation of enfuvirtide with an optimized background regimen
-
Bangkok, Thailand Abstract MoOrB1058
-
ARASTEH K, LAZZARIN A, CLOTET B et al.: TORO: 96 week virological and immunological response and safety evaluation of enfuvirtide with an optimized background regimen. XV International AIDS Conference. Bangkok, Thailand (2004). Abstract MoOrB1058.
-
(2004)
XV International AIDS Conference
-
-
Arasteh, K.1
Lazzarin, A.2
Clotet, B.3
-
62
-
-
17144407126
-
Early viral load responses on enfuvirtide in heavily treatment-experienced patients
-
Bangkok, Thailand Abstract TuPeB4484
-
BARTLETT JA, SALGO M, DEMASI R: Early viral load responses on enfuvirtide in heavily treatment-experienced patients. XV International AIDS Conference. Bangkok, Thailand (2004). Abstract TuPeB4484.
-
(2004)
XV International AIDS Conference
-
-
Bartlett, J.A.1
Salgo, M.2
Demasi, R.3
-
63
-
-
0347600772
-
Impact of enfuvirtide on health-related quality of life at 48 weeks
-
Warsaw, Poland Abstract 7.3/19
-
CLUMECK N, COHEN CJ, THOMPSON M et al.: Impact of enfuvirtide on health-related quality of life at 48 weeks. 9th European AIDS Conference. Warsaw, Poland (2003). Abstract 7.3/19.
-
(2003)
9th European AIDS Conference
-
-
Clumeck, N.1
Cohen, C.J.2
Thompson, M.3
-
64
-
-
1842461846
-
Impact of enfuvirtide on helath-related quality of life
-
COHEN CJ, CLUMECK N, MOLINA J-M, et al.: Impact of enfuvirtide on helath-related quality of life. Antivir. Ther. (2003) 8(Suppl. 1):S510.
-
(2003)
Antivir. Ther.
, vol.8
, Issue.SUPPL. 1
-
-
Cohen, C.J.1
Clumeck, N.2
Molina, J.-M.3
-
65
-
-
1642314025
-
Efficacy of enfuvirtide in subgroups of patients through 48 weeks of therapy in the TORO trials
-
Warsaw, Poland Abstract 7.3/15
-
WALMSLEY S, CLOTET B, COOPER D et al.: Efficacy of enfuvirtide in subgroups of patients through 48 weeks of therapy in the TORO trials. 9th European AIDS Conference. Warsaw, Poland (2003). Abstract 7.3/15.
-
(2003)
9th European AIDS Conference
-
-
Walmsley, S.1
Clotet, B.2
Cooper, D.3
-
67
-
-
20544435888
-
A treatment staging proposal derived from a post-hoc analysis of the 48 week results from the TORO studies
-
Bangkok, Thailand Abstract TuPeB4483
-
MONTANER J, CHUNG J, GUIMARAES D et al.: A treatment staging proposal derived from a post-hoc analysis of the 48 week results from the TORO studies. XV International AIDS Conference. Bangkok, Thailand (2004). Abstract TuPeB4483.
-
(2004)
XV International AIDS Conference
-
-
Montaner, J.1
Chung, J.2
Guimaraes, D.3
-
68
-
-
1642414599
-
Safety of enfuvirtide (ENF) through 48 weeks of therapy in the TORO trials
-
Chicago, IL, USA Abstract H-836
-
ERON JJ, DELFRAISSY JF, KURITZKES D, et al.: Safety of enfuvirtide (ENF) through 48 weeks of therapy in the TORO trials. 43rd Interscience Conference on Antimicrob. Agents Chemother. Chicago, IL, USA (2003). Abstract H-836.
-
(2003)
43rd Interscience Conference on Antimicrob. Agents Chemother.
-
-
Eron, J.J.1
Delfraissy, J.F.2
Kuritzkes, D.3
-
69
-
-
0142244854
-
Injection site reactions with the HIV-1 fusion inhibitor enfuvirtide
-
BALL RA, KINCHELOW T. Injection site reactions with the HIV-1 fusion inhibitor enfuvirtide. J. Am. Acad. Dermatol. (2003) 49 5):826-831.
-
(2003)
J. Am. Acad. Dermatol.
, vol.49
, Issue.5
, pp. 826-831
-
-
Ball, R.A.1
Kinchelow, T.2
-
70
-
-
2942583415
-
A prospective clinical and histological examination of injection sites with the HIV fusion inhibitor enfuvirtide (ENF)
-
Chicago, IL, USA Abstract H-2015
-
MYERS SA, SELIM A, MCDANIEL M, et al.: A prospective clinical and histological examination of injection sites with the HIV fusion inhibitor enfuvirtide (ENF). 43rd Interscience Conference on Antimicrob. Agents Chemother. Chicago, IL, USA (2003). Abstract H-2015.
-
(2003)
43rd Interscience Conference on Antimicrob. Agents Chemother.
-
-
Myers, S.A.1
Selim, A.2
McDaniel, M.3
-
71
-
-
2642581870
-
The effects of enfuvirtide therapy on body composition and serum lipids through 48 weeks in the TORO trials
-
San Francisco, USA Abstract 715
-
COOPER DA, REISS P, HENRY K et al.: The effects of enfuvirtide therapy on body composition and serum lipids through 48 weeks in the TORO trials. 11th Conference on Retroviruses and Opportunistic Infections. San Francisco, USA (2004). Abstract 715.
-
(2004)
11th Conference on Retroviruses and Opportunistic Infections
-
-
Cooper, D.A.1
Reiss, P.2
Henry, K.3
-
72
-
-
9144264190
-
Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide
-
WALMSLEY S, HENRY K, KATLAMA C et al.: Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide. J. Infect. Dis. (2003) 188 12):1827-1833.
-
(2003)
J. Infect. Dis.
, vol.188
, Issue.12
, pp. 1827-1833
-
-
Walmsley, S.1
Henry, K.2
Katlama, C.3
-
73
-
-
17144406247
-
Increase in serum IgE levels during enfuvirtide treatment in multidrug-resistant HIV-1 infected patients
-
Bangkok, Thailand Abstract
-
HASSON H, DANISE A, CARINI E et al.: Increase in serum IgE levels during enfuvirtide treatment in multidrug-resistant HIV-1 infected patients. XV International AIDS Conference. Bangkok, Thailand (2004). Abstract.
-
(2004)
XV International AIDS Conference
-
-
Hasson, H.1
Danise, A.2
Carini, E.3
-
74
-
-
17144381511
-
Incidence of baseline elevated serum IgE levels in the HIV-treatment-experienced population of the TORO studies remains stable during treatment and does not correlate with enfuvirtide (ENF) use
-
Washington DC, USA Poster H-170
-
WAT C, PANTALEO G, HERATH C et al.: Incidence of baseline elevated serum IgE levels in the HIV-treatment-experienced population of the TORO studies remains stable during treatment and does not correlate with enfuvirtide (ENF) use. 44th Interscience Conference on Antimicrob. Agents Chemother. Washington DC, USA (2004). Poster H-170.
-
(2004)
44th Interscience Conference on Antimicrob. Agents Chemother.
-
-
Wat, C.1
Pantaleo, G.2
Herath, C.3
-
75
-
-
3042726798
-
Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel
-
YENI PG, HAMMER SM, HIRSCH MS et al.: Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel. JAMA (2004) 292(2):251-265.
-
(2004)
JAMA
, vol.292
, Issue.2
, pp. 251-265
-
-
Yeni, P.G.1
Hammer, S.M.2
Hirsch, M.S.3
-
76
-
-
2542452668
-
Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and adolescents
-
Department of Health and Human Services. Panel on Clinical Practices for Treatment of HIV Infection
-
Department of Health and Human Services. Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and adolescents Panel on Clinical Practices for Treatment of HIV Infection (2004).
-
(2004)
-
-
-
77
-
-
0142248431
-
British HIV Association (BHIVA) guidelines for the treatment of HIV-infected adults with antiretroviral therapy
-
POZNIAK A, GAZZARD B, ANDERSON J. et al.: British HIV Association (BHIVA) guidelines for the treatment of HIV-infected adults with antiretroviral therapy. HIV Med. (2003) 4(Suppl. 1):1-41.
-
(2003)
HIV Med.
, vol.4
, Issue.SUPPL. 1
, pp. 1-41
-
-
Pozniak, A.1
Gazzard, B.2
Anderson, J.3
-
78
-
-
0036315615
-
Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: Patient satisfaction and impact on activities of daily living
-
COHEN CJ, DUSEK A, GREEN J. et al.: Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: patient satisfaction and impact on activities of daily living. AIDS Patient Care STDS (2002) 16(7):327-335.
-
(2002)
AIDS Patient Care STDS
, vol.16
, Issue.7
, pp. 327-335
-
-
Cohen, C.J.1
Dusek, A.2
Green, J.3
-
79
-
-
0036708580
-
Subcutaneous injection survey: Psychometric evaluation of a treatment satisfaction instrument associated with a novel HIV medication
-
GREEN J, KLEINMAN L, CIESLA G et al.: Subcutaneous injection survey: psychometric evaluation of a treatment satisfaction instrument associated with a novel HIV medication. HIV Clin. Trials (2002) 3(5):387-395.
-
(2002)
HIV Clin. Trials
, vol.3
, Issue.5
, pp. 387-395
-
-
Green, J.1
Kleinman, L.2
Ciesla, G.3
-
80
-
-
0142186214
-
Patient acceptance of self-injected enfuvirtide at 8 and 24 weeks
-
COHEN C, HELLINGER J, JOHNSON M et al.: Patient acceptance of self-injected enfuvirtide at 8 and 24 weeks. HIV Clin. Trials (2003) 4(5):347-357.
-
(2003)
HIV Clin. Trials
, vol.4
, Issue.5
, pp. 347-357
-
-
Cohen, C.1
Hellinger, J.2
Johnson, M.3
-
81
-
-
3042663633
-
Patient acceptance with self-injection of enfuvirtide (ENF) for HIV over 48 weeks of treatment
-
Warsaw, Poland Abstract 7.1/1
-
COHEN C, GREEN J, WINTFELD N, PATEL K: Patient acceptance with self-injection of enfuvirtide (ENF) for HIV over 48 weeks of treatment. 9th European AIDS Conference. Warsaw, Poland (2003). Abstract 7.1/1.
-
(2003)
9th European AIDS Conference
-
-
Cohen, C.1
Green, J.2
Wintfeld, N.3
Patel, K.4
|