Ether-lipid (alkyl-phospholipid) metabolism and the mechanism of action of ether-lipid analogues in Leishmania

Molecular and Biochemical Parasitology

Volumn 111, Issue 1, 2000, Pages 1-14

  Lux, Henning ^a   Heise, Norton ^b,c   Klenner, Thomas ^d   Hart, David ^a   Opperdoes, Fred R ^b,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b DE DUVE INSTITUTE   (Belgium)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^d ASTA Medica   (Germany)

Author keywords

Anti leishmanial activity; Edelfosine; Ether lipid biosynthesis; Miltefosine

Indexed keywords

1 ACYLGLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE; ACYLTRANSFERASE; DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; EDELFOSINE; ETHER PHOSPHOLIPID; MILTEFOSINE; PHOSPHOGLYCERATE KINASE; SYNTHETASE; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL CULTURE; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; LEISHMANIA; LEISHMANIA MEXICANA; LIPID METABOLISM; LIVER; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROMASTIGOTE; RAT;

ACYLATION; ACYLTRANSFERASES; ALCOHOL OXIDOREDUCTASES; ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTIPROTOZOAL AGENTS; LEISHMANIA MEXICANA; MICROBODIES; PHOSPHOLIPID ETHERS; PHOSPHORYLCHOLINE;

LEISHMANIA MEXICANA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

EID: 0033758270     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(00)00278-4     Document Type: Article

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