Mechanism of action of anti-proliferative lysophospholipid analogues against the protozoan parasite Trypanosoma cruzi: Potentiation of in vitro activity by the sterol biosynthesis inhibitor ketoconazole

Journal of Antimicrobial Chemotherapy

Volumn 47, Issue 5, 2001, Pages 537-546

  Lira, Rene ^a   Contreras, Lellys Mariela ^a   Santa Rita, Ricardo M ^b   Urbina, Julio A ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLLYSOPHOSPHOLIPID; CARBON 14; CHOLESTEROL; CHOLINE; ERGOSTEROL; ILMOFOSINE; KETOCONAZOLE; LYSOPHOSPHOLIPID; METHIONINE; METHYLTRANSFERASE; MILTEFOSINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; SPHINGOMYELIN; SQUALENE; STEROL;

AMASTIGOTE; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SELECTIVITY; DRUG STRUCTURE; EPIMASTIGOTE; IC 50; IN VITRO STUDY; LIPID COMPOSITION; LYSIS; NONHUMAN; RADIOACTIVITY; STEROL SYNTHESIS; TRYPANOSOMA CRUZI; VERO CELL;

EID: 0035025017     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/47.5.537     Document Type: Article

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