메뉴 건너뛰기




Volumn 36, Issue 12, 2008, Pages 2445-2451

Quantitative tissue and gene-specific differences and developmental changes in Nat1, Nat2, and Nat3 mRNA expression in the rat

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE; N ACETYLTRANSFERASE 1; N ACETYLTRANSFERASE 3; UNCLASSIFIED DRUG;

EID: 57349163483     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.023564     Document Type: Article
Times cited : (19)

References (25)
  • 1
    • 26444618665 scopus 로고    scopus 로고
    • Arylamine N-acetyltransferases: What we learn from genes and genomes
    • Boukouvala S and Fakis G (2005) Arylamine N-acetyltransferases: what we learn from genes and genomes. Drug Metab Rev 37:511-564.
    • (2005) Drug Metab Rev , vol.37 , pp. 511-564
    • Boukouvala, S.1    Fakis, G.2
  • 2
    • 0141444660 scopus 로고    scopus 로고
    • Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice
    • Boukouvala S, Price N, Plant KE, and Sim E (2003) Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice. Biochem J 375:593-602.
    • (2003) Biochem J , vol.375 , pp. 593-602
    • Boukouvala, S.1    Price, N.2    Plant, K.E.3    Sim, E.4
  • 3
    • 0028871138 scopus 로고
    • Complementary DNAs for two arylamine N-acetyltransferases with identical 5′ non-coding regions from rat pineal gland
    • Ebisawa T, Sasaki Y, and Deguchi T (1995) Complementary DNAs for two arylamine N-acetyltransferases with identical 5′ non-coding regions from rat pineal gland. Eur J Biochem 228:129-137.
    • (1995) Eur J Biochem , vol.228 , pp. 129-137
    • Ebisawa, T.1    Sasaki, Y.2    Deguchi, T.3
  • 4
    • 0033967807 scopus 로고    scopus 로고
    • Tissue- and gender-specific expression of N-acetyltransferase 2 (Nat2*) during development of the outbred mouse strain CD-1
    • Estrada L, Kanelakis KC, Levy GN, and Weber WW (2000) Tissue- and gender-specific expression of N-acetyltransferase 2 (Nat2*) during development of the outbred mouse strain CD-1. Drug Metab Dispos 28:139-146.
    • (2000) Drug Metab Dispos , vol.28 , pp. 139-146
    • Estrada, L.1    Kanelakis, K.C.2    Levy, G.N.3    Weber, W.W.4
  • 5
    • 0031902933 scopus 로고    scopus 로고
    • Substrate selectivity of mouse N-acetyltransferases 1, 2, and 3 expressed in COS-1 cells
    • Estrada-Rodgers L, Levy GN, and Weber WW (1998) Substrate selectivity of mouse N-acetyltransferases 1, 2, and 3 expressed in COS-1 cells. Drug Metab Dispos 26:502-505.
    • (1998) Drug Metab Dispos , vol.26 , pp. 502-505
    • Estrada-Rodgers, L.1    Levy, G.N.2    Weber, W.W.3
  • 6
    • 0031062306 scopus 로고    scopus 로고
    • Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: Functional characterization of the activation and deactivation of aromatic amine carcinogens
    • Fretland AJ, Doll MA, Gray K, Feng Y, and Hein DW (1997) Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens. Toxicol Appl Pharmacol 142:360-366.
    • (1997) Toxicol Appl Pharmacol , vol.142 , pp. 360-366
    • Fretland, A.J.1    Doll, M.A.2    Gray, K.3    Feng, Y.4    Hein, D.W.5
  • 7
    • 0028190698 scopus 로고
    • N-Acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: Enzymology and bioactivation
    • Hanna PE (1994) N-Acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation. Adv Pharmacol 27:401-430.
    • (1994) Adv Pharmacol , vol.27 , pp. 401-430
    • Hanna, P.E.1
  • 8
    • 0023812845 scopus 로고
    • Acetylator genotype and arylamine-induced carcinogenesis
    • Hein DW (1988) Acetylator genotype and arylamine-induced carcinogenesis. Biochim Biophys Acta 948:37-66.
    • (1988) Biochim Biophys Acta , vol.948 , pp. 37-66
    • Hein, D.W.1
  • 9
    • 0034653350 scopus 로고    scopus 로고
    • N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis
    • Hein DW (2000) N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis. Toxicol Lett 112-113:349-356.
    • (2000) Toxicol Lett , vol.112-113 , pp. 349-356
    • Hein, D.W.1
  • 12
    • 33645453469 scopus 로고    scopus 로고
    • Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster
    • Hein DW, Doll MA, Nerland DE, and Fretland AJ (2006) Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster. Mol Carcinog 45:230-238.
    • (2006) Mol Carcinog , vol.45 , pp. 230-238
    • Hein, D.W.1    Doll, M.A.2    Nerland, D.E.3    Fretland, A.J.4
  • 13
    • 0025851043 scopus 로고
    • Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model
    • Hein DW, Rustan TD, Bucher KD, Furman EJ, and Martin WJ (1991a) Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model. J Pharmacol Exp Ther 258:232-236.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 232-236
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Furman, E.J.4    Martin, W.J.5
  • 14
    • 0026077162 scopus 로고
    • Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver
    • Hein DW, Rustan TD, Bucher KD, Martin WJ, and Furman EJ (1991b) Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver. Drug Metab Dispos 19:933-937.
    • (1991) Drug Metab Dispos , vol.19 , pp. 933-937
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Martin, W.J.4    Furman, E.J.5
  • 15
    • 34548059291 scopus 로고    scopus 로고
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007a) Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements. Drug Metab Dispos 35:1649-1656.
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007a) Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements. Drug Metab Dispos 35:1649-1656.
  • 16
    • 34247323530 scopus 로고    scopus 로고
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007b) Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues. Drug Metab Dispos 35:721-727.
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007b) Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues. Drug Metab Dispos 35:721-727.
  • 18
    • 0028061086 scopus 로고
    • Arylamine N-acetyltransferase in BALB/c mice: Identification of a novel mouse isoenzyme by cloning and expression in vitro
    • Kelly SL and Sim E (1994) Arylamine N-acetyltransferase in BALB/c mice: identification of a novel mouse isoenzyme by cloning and expression in vitro. Biochem J 302 (Pt 2):347-353.
    • (1994) Biochem J , vol.302 , Issue.PART 2 , pp. 347-353
    • Kelly, S.L.1    Sim, E.2
  • 20
    • 0038172501 scopus 로고    scopus 로고
    • Neonatal ontogeny of murine arylamine N-acetyltransferases: Implications for arylamine genotoxicity
    • McQueen CA and Chau B (2003) Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity. Toxicol Sci 73:279-286.
    • (2003) Toxicol Sci , vol.73 , pp. 279-286
    • McQueen, C.A.1    Chau, B.2
  • 23
    • 0037561531 scopus 로고    scopus 로고
    • Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice
    • Sugamori KS, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, and Grant DM (2003) Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice. Mol Pharmacol 64:170-179.
    • (2003) Mol Pharmacol , vol.64 , pp. 170-179
    • Sugamori, K.S.1    Wong, S.2    Gaedigk, A.3    Yu, V.4    Abramovici, H.5    Rozmahel, R.6    Grant, D.M.7
  • 24
    • 38449091987 scopus 로고    scopus 로고
    • Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and functional characterization of a novel rNat3*2 genetic variant
    • Walraven JM, Barker DF, Doll MA, and Hein DW (2007) Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and functional characterization of a novel rNat3*2 genetic variant. Toxicol Sci 99:413-421.
    • (2007) Toxicol Sci , vol.99 , pp. 413-421
    • Walraven, J.M.1    Barker, D.F.2    Doll, M.A.3    Hein, D.W.4
  • 25
    • 33749010107 scopus 로고    scopus 로고
    • Identification and characterization of functional rat arylamine N-acetyltransferase 3: Comparisons with rat arylamine N-acetyltransferases 1 and 2
    • Walraven JM, Doll MA, and Hein DW (2006) Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2. J Pharmacol Exp Ther 319:369-375.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 369-375
    • Walraven, J.M.1    Doll, M.A.2    Hein, D.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.