Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice

Biochemical Journal

Volumn 375, Issue 3, 2003, Pages 593-602

  Boukouvala, Sotiria ^a   Price, Naomi ^a   Plant, Kathryn E ^b   Sim, Edith ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Arylamine; Arylamine N acetyltransferase; Drug metabolism; Murine Nat2 promoter; N acetylation; Xenobiotic metabolizing enzyme gene expression

Indexed keywords

BRAIN; CELLS; CYTOLOGY; DNA; DRUG PRODUCTS; GENES; METABOLISM;

MURINES; POLYMORPHIC ENZYMES;

ENZYMES;

ARYLAMINE ACETYLTRANSFERASE; COMPLEMENTARY DNA; DRUG METABOLIZING ENZYME;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXON; GENE; GENE ACTIVITY; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE MAPPING; GENE MUTATION; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSCRIPTION; MOUSE; NAT2 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; XENOBIOTIC METABOLISM;

ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; BINDING SITES; BLOTTING, WESTERN; CELL LINE; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES; ISOENZYMES; MICE; MICE, INBRED BALB C; PROMOTER REGIONS (GENETICS); REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

ANIMALIA; MURINAE; SIMIAE; SIMIAN VIRUS 40;

EID: 0141444660     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030812     Document Type: Article

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