메뉴 건너뛰기




Volumn 45, Issue 4, 2006, Pages 230-238

Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster

Author keywords

Acetylation polymorphism; Bladder cancer; NAT2 genotype; Pancreatic cancer

Indexed keywords

4 AMINOBENZOIC ACID; 4 BIPHENYLAMINE; ACYLTRANSFERASE; AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE; BIPHENYL DERIVATIVE; HYDROXYL GROUP; N ACETYLTRANSFERASE 1; N HYDROXY 4 BIPHENYLAMINE; SULFADIMIDINE; UNCLASSIFIED DRUG;

EID: 33645453469     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20164     Document Type: Article
Times cited : (50)

References (58)
  • 1
    • 0023812845 scopus 로고
    • Acetylator genotype and arylamine-induced carcinogenesis
    • Hein DW. Acetylator genotype and arylamine-induced carcinogenesis. Biochim Biophys Acta 1988;948:37-66.
    • (1988) Biochim Biophys Acta , vol.948 , pp. 37-66
    • Hein, D.W.1
  • 2
    • 0021813284 scopus 로고
    • N-Acetylation pharmacogenetics
    • Weber WW, Hein DW. N-Acetylation pharmacogenetics. Pharmacol Revs 1985;37:25-79.
    • (1985) Pharmacol Revs , vol.37 , pp. 25-79
    • Weber, W.W.1    Hein, D.W.2
  • 3
    • 0033960051 scopus 로고    scopus 로고
    • Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms
    • Hein DW, Doll MA, Fretland AJ, et al. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol Biomarkers Prev 2000;9:29-42.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 29-42
    • Hein, D.W.1    Doll, M.A.2    Fretland, A.J.3
  • 5
    • 0037201542 scopus 로고    scopus 로고
    • Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis
    • Hein DW. Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis. Mutat Res 2002;506-507:65-77.
    • (2002) Mutat Res , vol.506-507 , pp. 65-77
    • Hein, D.W.1
  • 6
    • 3242880312 scopus 로고    scopus 로고
    • Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: Role of genetic and non genetic factors
    • Rodrigues-Lima F, Dupret JM. Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: Role of genetic and non genetic factors. Curr Pharm Des 2004;10:2519-2524.
    • (2004) Curr Pharm des , vol.10 , pp. 2519-2524
    • Rodrigues-Lima, F.1    Dupret, J.M.2
  • 7
    • 12644293822 scopus 로고    scopus 로고
    • Rodent models of the human acetylation polymorphism: Comparisons of recombinant acetyltransferases
    • Hein DW, Doll MA, Fretland AJ, et al. Rodent models of the human acetylation polymorphism: Comparisons of recombinant acetyltransferases. Mut Res 1997;376:101-106.
    • (1997) Mut Res , vol.376 , pp. 101-106
    • Hein, D.W.1    Doll, M.A.2    Fretland, A.J.3
  • 8
    • 0020042254 scopus 로고
    • A unique pharmacogenetic expression of the N-acetylation polymorphism in the inbred hamster
    • Hein DW, Omichinski JG, Brewer JA, Weber WW. A unique pharmacogenetic expression of the N-acetylation polymorphism in the inbred hamster. J Pharmacol Exp Ther 1982;220:8-15.
    • (1982) J Pharmacol Exp Ther , vol.220 , pp. 8-15
    • Hein, D.W.1    Omichinski, J.G.2    Brewer, J.A.3    Weber, W.W.4
  • 9
    • 0025967717 scopus 로고
    • Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
    • Grant DM, Beer M, Blum M, Meyer UA. Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes. Mol Pharmacol 1991;39:184-191.
    • (1991) Mol Pharmacol , vol.39 , pp. 184-191
    • Grant, D.M.1    Beer, M.2    Blum, M.3    Meyer, U.A.4
  • 10
    • 0027281895 scopus 로고
    • Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
    • Hein DW, Doll MA, Rustan TD, et al. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 1993;14:1633-1638.
    • (1993) Carcinogenesis , vol.14 , pp. 1633-1638
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3
  • 11
    • 0028358566 scopus 로고
    • Syrian hamster monomorphic n-acetyltransferase (NAT1) alleles: Amplification, cloning, sequencing, and expression in E. coli
    • Ferguson RJ, Doll MA, Rustan TD, Baumstark BR, Hein DW. Syrian hamster monomorphic n-acetyltransferase (NAT1) alleles: Amplification, cloning, sequencing, and expression in E. coli. Pharmacogenetics 1994;4:82-90.
    • (1994) Pharmacogenetics , vol.4 , pp. 82-90
    • Ferguson, R.J.1    Doll, M.A.2    Rustan, T.D.3    Baumstark, B.R.4    Hein, D.W.5
  • 12
    • 0025793325 scopus 로고
    • An arylamine acetyltransferase (AT-I) from Syrian golden hamster liver: Cloning, complete nucleotide sequence, and expression in mammalian cells
    • Abu-Zeid M, Nagata K, Miyata M, et al. An arylamine acetyltransferase (AT-I) from Syrian golden hamster liver: Cloning, complete nucleotide sequence, and expression in mammalian cells. Mol Carcinogenesis 1991;4:81-88.
    • (1991) Mol Carcinogenesis , vol.4 , pp. 81-88
    • Abu-Zeid, M.1    Nagata, K.2    Miyata, M.3
  • 13
    • 0029869584 scopus 로고    scopus 로고
    • Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyltransferase encoding genes of the Syrian hamster
    • Ferguson RJ, Doll MA, Rustan TD, Hein DW. Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyltransferase encoding genes of the Syrian hamster. Pharmacogenetics 1996;6:55-66.
    • (1996) Pharmacogenetics , vol.6 , pp. 55-66
    • Ferguson, R.J.1    Doll, M.A.2    Rustan, T.D.3    Hein, D.W.4
  • 15
    • 0027246519 scopus 로고
    • Primary aromatic amines from side-stream cigarette smoke are common contaminants of indoor air
    • Luceri F, Pieraccini G, Moneti G, Dolara P. Primary aromatic amines from side-stream cigarette smoke are common contaminants of indoor air. Toxicol Ind Health 1993;9:405-413.
    • (1993) Toxicol Ind Health , vol.9 , pp. 405-413
    • Luceri, F.1    Pieraccini, G.2    Moneti, G.3    Dolara, P.4
  • 16
    • 0033044237 scopus 로고    scopus 로고
    • Mutagenicity and aromatic amine content of fumes from heated cooking oils produced in Taiwan
    • Chiang TA, Pei-Fen W, Ying LS, Wang LF, Ko YC. Mutagenicity and aromatic amine content of fumes from heated cooking oils produced in Taiwan. Food Chem Toxicol 1999;37:125-134.
    • (1999) Food Chem Toxicol , vol.37 , pp. 125-134
    • Chiang, T.A.1    Pei-Fen, W.2    Ying, L.S.3    Wang, L.F.4    Ko, Y.C.5
  • 17
    • 0038032435 scopus 로고    scopus 로고
    • United States Department of Health and Human Services, Public Health Service
    • National Toxicology Program. Report on Carcinogens. Eleventh Edition, United States Department of Health and Human Services, Public Health Service. 2005.
    • (2005) Report on Carcinogens. Eleventh Edition
  • 18
    • 0028224431 scopus 로고
    • Acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in White, Black, and Asian men in Los Angeles, California
    • Yu MC, Skipper PL, Taghizadeh K, et al. Acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in White, Black, and Asian men in Los Angeles, California. J Natl Cancer Inst 1994;86:712-716.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 712-716
    • Yu, M.C.1    Skipper, P.L.2    Taghizadeh, K.3
  • 19
    • 0035117747 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms, metabolic activation and environmental carcinogenesis: Why molecular epidemiologists should think about enzyme expression
    • Williams JA. Single nucleotide polymorphisms, metabolic activation and environmental carcinogenesis: Why molecular epidemiologists should think about enzyme expression. Carcinogenesis 2001;22:209-214.
    • (2001) Carcinogenesis , vol.22 , pp. 209-214
    • Williams, J.A.1
  • 20
    • 0015597281 scopus 로고
    • Multiple N-acetyltransferases and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase
    • Hearse DJ, Weber WW. Multiple N-acetyltransferases and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase. Biochem J 1973;132:519-526.
    • (1973) Biochem J , vol.132 , pp. 519-526
    • Hearse, D.J.1    Weber, W.W.2
  • 22
    • 0026040316 scopus 로고
    • Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon
    • Turesky RJ, Lang NP, Butler MA, Teitel CH, Kadlubar FF. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. Carcinogenesis 1991;12:1839-1845.
    • (1991) Carcinogenesis , vol.12 , pp. 1839-1845
    • Turesky, R.J.1    Lang, N.P.2    Butler, M.A.3    Teitel, C.H.4    Kadlubar, F.F.5
  • 23
    • 0025962119 scopus 로고
    • Acetylator genotype-dependent expression of arylamine N-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients
    • Kirlin WG, Ogolla F, Andrews AF, et al. Acetylator genotype-dependent expression of arylamine N-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients. Cancer Res 1991;51:549-555.
    • (1991) Cancer Res , vol.51 , pp. 549-555
    • Kirlin, W.G.1    Ogolla, F.2    Andrews, A.F.3
  • 24
    • 0028198167 scopus 로고
    • Expression of monomorphic and polymorphic N-acetyltransferases in human colon
    • Ilett KF, Ingram DM, Carpenter DS, et al. Expression of monomorphic and polymorphic N-acetyltransferases in human colon. Biochem Pharmacol 1994;47:914-917.
    • (1994) Biochem Pharmacol , vol.47 , pp. 914-917
    • Ilett, K.F.1    Ingram, D.M.2    Carpenter, D.S.3
  • 25
    • 0031969231 scopus 로고    scopus 로고
    • Expression of arylamine N-acetyltransferase in human intestine
    • Hickman D, Pope J, Patil SD, et al. Expression of arylamine N-acetyltransferase in human intestine. Gut 1998;42:402-409.
    • (1998) Gut , vol.42 , pp. 402-409
    • Hickman, D.1    Pope, J.2    Patil, S.D.3
  • 27
    • 0025851043 scopus 로고
    • Extrahepatic expression of the N-acetylation polymorphism towards arylamine carcinogens in tumor target organs of an inbred rat model
    • Hein DW, Rustan TD, Bucher KD, Furman EJ, Martin WJ. Extrahepatic expression of the N-acetylation polymorphism towards arylamine carcinogens in tumor target organs of an inbred rat model. J Pharmacol Exp Ther 1991;258:232-236.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 232-236
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Furman, E.J.4    Martin, W.J.5
  • 29
    • 0030960852 scopus 로고    scopus 로고
    • Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice
    • Stanley LA, Mills IG, Sim E. Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice. Pharmacogenetics 1997;7:121-130.
    • (1997) Pharmacogenetics , vol.7 , pp. 121-130
    • Stanley, L.A.1    Mills, I.G.2    Sim, E.3
  • 30
    • 0037561531 scopus 로고    scopus 로고
    • Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice
    • Sugamori KS, Wong S, Gaedigk A, et al. Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice. Mol Pharmacol 2003;64:170-179.
    • (2003) Mol Pharmacol , vol.64 , pp. 170-179
    • Sugamori, K.S.1    Wong, S.2    Gaedigk, A.3
  • 31
    • 0026319473 scopus 로고
    • Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus
    • Hein DW, Rustan TD, Bucher KD, Miller LS. Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus. J Pharmacol Exp Ther 1991;259:699-704.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 699-704
    • Hein, D.W.1    Rustan, T.D.2    Bucher, K.D.3    Miller, L.S.4
  • 32
    • 0028301762 scopus 로고
    • Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): Acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens
    • Hein DW, Doll MA, Rustan TD, Gray K, Ferguson RJ, Feng Y. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): Acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens. Toxicol Appl Pharmacol 1994;124:16-24.
    • (1994) Toxicol Appl Pharmacol , vol.124 , pp. 16-24
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3    Gray, K.4    Ferguson, R.J.5    Feng, Y.6
  • 33
    • 0002063453 scopus 로고
    • A new model for toxic risk assessments: Construction of homozygous rapid and slow acetylator congenic Syrian hamster lines
    • Hein DW. A new model for toxic risk assessments: Construction of homozygous rapid and slow acetylator congenic Syrian hamster lines. Toxicol Meth 1991;1:44-52.
    • (1991) Toxicol Meth , vol.1 , pp. 44-52
    • Hein, D.W.1
  • 34
    • 0028207404 scopus 로고
    • Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters
    • Ferguson RJ, Doll MA, Rustan TD, Baumstark BR, Hein DW. Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters. Gene 1994;140:247-249.
    • (1994) Gene , vol.140 , pp. 247-249
    • Ferguson, R.J.1    Doll, M.A.2    Rustan, T.D.3    Baumstark, B.R.4    Hein, D.W.5
  • 35
    • 0032967592 scopus 로고    scopus 로고
    • Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse
    • Leff MA, Epstein PN, Doll MA, et al. Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse. J Pharmacol Exp Ther 1999;290:182-187.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 182-187
    • Leff, M.A.1    Epstein, P.N.2    Doll, M.A.3
  • 36
    • 0036952798 scopus 로고    scopus 로고
    • Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: Implications for cancer predisposition
    • Fretland AJ, Doll MA, Zhu Y, Smith L, Leff MA, Hein DW. Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: Implications for cancer predisposition. Cancer Detect Prev 2002;26:10-14.
    • (2002) Cancer Detect Prev , vol.26 , pp. 10-14
    • Fretland, A.J.1    Doll, M.A.2    Zhu, Y.3    Smith, L.4    Leff, M.A.5    Hein, D.W.6
  • 37
    • 33645449782 scopus 로고    scopus 로고
    • Recombinant expression of rat, hamster and mouse N-acetyltransferase 2 (NAT2) rapid and slow acetylator phenotypes in yeast
    • Xiao GH, Doll MA, Fretland AJ, Webb SJ, Hein DW. Recombinant expression of rat, hamster and mouse N-acetyltransferase 2 (NAT2) rapid and slow acetylator phenotypes in yeast. Proc Ninth North Amer ISSX Meeting 1999;15:130.
    • (1999) Proc Ninth North Amer ISSX Meeting , vol.15 , pp. 130
    • Xiao, G.H.1    Doll, M.A.2    Fretland, A.J.3    Webb, S.J.4    Hein, D.W.5
  • 38
    • 0030598397 scopus 로고    scopus 로고
    • Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat. Evidence for multiplicity of N-acetyltransferases in the intestine
    • Ware JA, Svensson CK. Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat. Evidence for multiplicity of N-acetyltransferases in the intestine. Biochem Pharmacol 1996;52:1613-1620.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1613-1620
    • Ware, J.A.1    Svensson, C.K.2
  • 39
    • 0022415085 scopus 로고
    • Biochemical investigation of the basis for the genetic N-acetylation polymorphism in the inbred hamster
    • Hein DW, Kirlin WG, Ferguson RJ, Weber WW. Biochemical investigation of the basis for the genetic N-acetylation polymorphism in the inbred hamster. J Pharmacol Exp Ther 1985;234:358-364.
    • (1985) J Pharmacol Exp Ther , vol.234 , pp. 358-364
    • Hein, D.W.1    Kirlin, W.G.2    Ferguson, R.J.3    Weber, W.W.4
  • 40
    • 0023011568 scopus 로고
    • N-acetyltransferase multiplicity and bioactivation of N-arylhydroxamic acids by hamster hepatic and intestinal enzymes
    • Smith TJ, Hanna PE. N-acetyltransferase multiplicity and bioactivation of N-arylhydroxamic acids by hamster hepatic and intestinal enzymes. Carcinogenesis 1986;7:697-702.
    • (1986) Carcinogenesis , vol.7 , pp. 697-702
    • Smith, T.J.1    Hanna, P.E.2
  • 41
    • 0024370471 scopus 로고
    • Kinetic characterization of acetylator genotype-dependent and -independent N-acetyltransferase isozymes in homozygous rapid and slow acetylator inbred hamster liver cytosol
    • Trinidad A, Kirlin WG, Ogolla F, et al. Kinetic characterization of acetylator genotype-dependent and -independent N-acetyltransferase isozymes in homozygous rapid and slow acetylator inbred hamster liver cytosol. Drug Metab Dispos 1989;17:238-247.
    • (1989) Drug Metab Dispos , vol.17 , pp. 238-247
    • Trinidad, A.1    Kirlin, W.G.2    Ogolla, F.3
  • 42
    • 0025695732 scopus 로고
    • Monomorphic and polymorphic isozymes of arylamine N-acetyltransferases in hamster liver: Purification of the isozymes and genetic basis of N-acetylation polymorphism
    • Ozawa S, Abu-Zeid M, Kawakubo Y, Toyama S, Yamazoe Y, Kato R. Monomorphic and polymorphic isozymes of arylamine N-acetyltransferases in hamster liver: Purification of the isozymes and genetic basis of N-acetylation polymorphism. Carcinogenesis 1990;11:2137-2144.
    • (1990) Carcinogenesis , vol.11 , pp. 2137-2144
    • Ozawa, S.1    Abu-Zeid, M.2    Kawakubo, Y.3    Toyama, S.4    Yamazoe, Y.5    Kato, R.6
  • 43
    • 0027477877 scopus 로고
    • Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus
    • Hein DW, Doll MA, Gray K, Rustan TD, Ferguson RJ. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus. Cancer Res 1993;53:509-514.
    • (1993) Cancer Res , vol.53 , pp. 509-514
    • Hein, D.W.1    Doll, M.A.2    Gray, K.3    Rustan, T.D.4    Ferguson, R.J.5
  • 44
    • 0024328530 scopus 로고
    • Identification and kinetic characterization of acetylator genotype-dependent and -independent arylamine carcinogen N-acetyltransferases in hamster bladder cytosol
    • Yerokun T, Kirlin WG, Trinidad A, et al. Identification and kinetic characterization of acetylator genotype-dependent and -independent arylamine carcinogen N-acetyltransferases in hamster bladder cytosol. Drug Metab Dispos 1989;17:231-237.
    • (1989) Drug Metab Dispos , vol.17 , pp. 231-237
    • Yerokun, T.1    Kirlin, W.G.2    Trinidad, A.3
  • 45
    • 0037339213 scopus 로고    scopus 로고
    • Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster
    • Hein DW, Doll MA, Xiao GH, Feng Y. Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster. Pharmacogenetics 2003;13:159-167.
    • (2003) Pharmacogenetics , vol.13 , pp. 159-167
    • Hein, D.W.1    Doll, M.A.2    Xiao, G.H.3    Feng, Y.4
  • 46
    • 0023096171 scopus 로고
    • Extrahepatic expression of N-acetylator genotype in the inbred hamster
    • Hein DW, Kirlin WG, Ogolla F, Trinidad A. Extrahepatic expression of N-acetylator genotype in the inbred hamster. Drug Metab Dispos 1987;15:68-73.
    • (1987) Drug Metab Dispos , vol.15 , pp. 68-73
    • Hein, D.W.1    Kirlin, W.G.2    Ogolla, F.3    Trinidad, A.4
  • 47
    • 0023640953 scopus 로고
    • Acetylator genotype dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: Relationship to arylamine N-acetyltransferase
    • Hein DW, Flammang TJ, Kirlin WG, Trinidad A, Ogolla F. Acetylator genotype dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: Relationship to arylamine N-acetyltransferase. Carcinogenesis 1987;8:1767-1774.
    • (1987) Carcinogenesis , vol.8 , pp. 1767-1774
    • Hein, D.W.1    Flammang, T.J.2    Kirlin, W.G.3    Trinidad, A.4    Ogolla, F.5
  • 48
    • 0025039194 scopus 로고
    • Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxy-arylamine O-acetyltransferase in Syrian inbred hamster intestine and colon: Identity with the hepatic acetylation polymorphism
    • Ogolla F, Ferguson RJ, Kirlin WG, et al. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxy-arylamine O-acetyltransferase in Syrian inbred hamster intestine and colon: Identity with the hepatic acetylation polymorphism. Drug Metab Dispos 1990;18:680-685.
    • (1990) Drug Metab Dispos , vol.18 , pp. 680-685
    • Ogolla, F.1    Ferguson, R.J.2    Kirlin, W.G.3
  • 49
    • 0043092254 scopus 로고    scopus 로고
    • Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo [4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus
    • Fretland AJ, Devanaboyina US, Doll MA, Zhao S, Xiao GH, Hein DW. Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo [4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus. Toxicol Sci 2003;74:253-259.
    • (2003) Toxicol Sci , vol.74 , pp. 253-259
    • Fretland, A.J.1    Devanaboyina, U.S.2    Doll, M.A.3    Zhao, S.4    Xiao, G.H.5    Hein, D.W.6
  • 50
    • 0026650976 scopus 로고
    • N- and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells
    • Minchin RF, Reeves PT, Teitel CH, et al. N- and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells. Biochem Biophys Res Comm 1992;185:839-844.
    • (1992) Biochem Biophys Res Comm , vol.185 , pp. 839-844
    • Minchin, R.F.1    Reeves, P.T.2    Teitel, C.H.3
  • 51
    • 0029117480 scopus 로고
    • Metabolic activation of N-hydroxyaryiamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: Effects of 7 specific NAT2 nucleic acid substitutions
    • Hein DW, Doll MA, Rustan TD, Ferguson RJ. Metabolic activation of N-hydroxyaryiamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: Effects of 7 specific NAT2 nucleic acid substitutions. Cancer Res 1995;55:3531-3536.
    • (1995) Cancer Res , vol.55 , pp. 3531-3536
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3    Ferguson, R.J.4
  • 52
    • 0036797382 scopus 로고    scopus 로고
    • 4-Aminobiphenyl is a major etiological agent of human bladder cancer: Evidence from its DNA binding spectrum in human p53 gene
    • Feng Z, Hu W, Rom WN, Beland FA, Tang MS. 4-aminobiphenyl is a major etiological agent of human bladder cancer: Evidence from its DNA binding spectrum in human p53 gene. Cardnogenesis 2002;23:1721-1727.
    • (2002) Cardnogenesis , vol.23 , pp. 1721-1727
    • Feng, Z.1    Hu, W.2    Rom, W.N.3    Beland, F.A.4    Tang, M.S.5
  • 53
    • 0028879678 scopus 로고
    • Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder
    • Badawi AF, Bell DA, Hirvonen A, Kadlubar FF. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder. Cancer Res 1995;55:5230-5237.
    • (1995) Cancer Res , vol.55 , pp. 5230-5237
    • Badawi, A.F.1    Bell, D.A.2    Hirvonen, A.3    Kadlubar, F.F.4
  • 54
    • 0024500474 scopus 로고
    • Polymorphic expression of AcCoA-dependent arylamine N-acetyltransferase and AcCoA-dependent O-acetyltransferase activation of N-hydroxyarylamines by human bladder cytosol
    • Kirlin WG, Trinidad A, Yerokun T, et al. Polymorphic expression of AcCoA-dependent arylamine N-acetyltransferase and AcCoA-dependent O-acetyltransferase activation of N-hydroxyarylamines by human bladder cytosol. Cancer Res 1989;49:2448-2454.
    • (1989) Cancer Res , vol.49 , pp. 2448-2454
    • Kirlin, W.G.1    Trinidad, A.2    Yerokun, T.3
  • 55
    • 0031426390 scopus 로고    scopus 로고
    • Metabolic activation of aromatic amines by human pancreas
    • Anderson KE, Hammons GJ, Kadlubar FF, et al. Metabolic activation of aromatic amines by human pancreas. Carcinogenesis 1997;18:1085-1092.
    • (1997) Carcinogenesis , vol.18 , pp. 1085-1092
    • Anderson, K.E.1    Hammons, G.J.2    Kadlubar, F.F.3
  • 56
    • 0033535441 scopus 로고    scopus 로고
    • Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype
    • 1999
    • Thompson PA, Seyedi F, Lang NP, et al. 1999. Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotype. Mutat Res 1999;424:263-274.
    • (1999) Mutat Res , vol.424 , pp. 263-274
    • Thompson, P.A.1    Seyedi, F.2    Lang, N.P.3
  • 57
    • 17644366799 scopus 로고    scopus 로고
    • Detection and quantification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human pancreas tissue with capillary liquid chromatography- microelectrospray mass spectrometry
    • Ricicki EM, Soglia JR, Teitel C, Kane R, Kadlubar F, Vouros P. Detection and quantification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human pancreas tissue with capillary liquid chromatography-microelectrospray mass spectrometry. Chem Res Toxicol 2005;18:692-699.
    • (2005) Chem Res Toxicol , vol.18 , pp. 692-699
    • Ricicki, E.M.1    Soglia, J.R.2    Teitel, C.3    Kane, R.4    Kadlubar, F.5    Vouros, P.6
  • 58
    • 28844445496 scopus 로고    scopus 로고
    • Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking and risk of pancreatic cancer
    • Epub ahead of print June 29, 2005
    • Li D, Jiao L, Li Y, et al. Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking and risk of pancreatic cancer. Carcinogenesis 2005 (Epub ahead of print June 29, 2005). 239-249
    • (2005) Carcinogenesis , pp. 239-249
    • Li, D.1    Jiao, L.2    Li, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.