메뉴 건너뛰기




Volumn 5, Issue 4, 2008, Pages 212-215

Telomerase biogenesis: The long road before getting to the end

Author keywords

hTERT; hTR; RNA trafficking; Telomerase biogenesis; Telomeres; TLC1

Indexed keywords

MESSENGER RNA; RIBONUCLEOPROTEIN; RNA; TELOMERASE;

EID: 57349096309     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.7115     Document Type: Review
Times cited : (29)

References (48)
  • 1
    • 34250841785 scopus 로고    scopus 로고
    • Replication and protection of telomeres
    • Verdun RE, Karlseder J. Replication and protection of telomeres. Nature 2007; 447:924-31.
    • (2007) Nature , vol.447 , pp. 924-931
    • Verdun, R.E.1    Karlseder, J.2
  • 2
    • 33745862398 scopus 로고    scopus 로고
    • The biogenesis and regulation of telomerase holoenzymes
    • Collins K. The biogenesis and regulation of telomerase holoenzymes. Nat Rev Mol Cell Biol 2006; 7:484-94.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 484-494
    • Collins, K.1
  • 3
    • 33745849998 scopus 로고    scopus 로고
    • The Structure and Function of Telomerase Reverse Transcriptase
    • Autexier C, Lue NF. The Structure and Function of Telomerase Reverse Transcriptase. Annu Rev Biochem 2006; 75:493-517.
    • (2006) Annu Rev Biochem , vol.75 , pp. 493-517
    • Autexier, C.1    Lue, N.F.2
  • 7
    • 0030721677 scopus 로고    scopus 로고
    • Polyadenylation of telomerase RNA in budding yeast
    • Chapon C, Cech TR, Zaug AJ. Polyadenylation of telomerase RNA in budding yeast. RNA 1997; 3:1337-51.
    • (1997) RNA , vol.3 , pp. 1337-1351
    • Chapon, C.1    Cech, T.R.2    Zaug, A.J.3
  • 8
    • 0033539171 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
    • Seto AG, Zaug AJ, Sobel SG, Wolin SL, Cech TR. Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature 1999; 401:177-80.
    • (1999) Nature , vol.401 , pp. 177-180
    • Seto, A.G.1    Zaug, A.J.2    Sobel, S.G.3    Wolin, S.L.4    Cech, T.R.5
  • 9
    • 2142819496 scopus 로고    scopus 로고
    • Why do cells need an assembly machine for RNA-protein complexes?
    • Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol 2004; 14:226-32.
    • (2004) Trends Cell Biol , vol.14 , pp. 226-232
    • Yong, J.1    Wan, L.2    Dreyfuss, G.3
  • 11
    • 3042798454 scopus 로고    scopus 로고
    • Yeast telomerase RNA: A flexible scaffold for protein subunits
    • Zappulla DC, Cech TR. Yeast telomerase RNA: A flexible scaffold for protein subunits. Proc Nat Acad Sci USA 2004; 101:10024-9.
    • (2004) Proc Nat Acad Sci USA , vol.101 , pp. 10024-10029
    • Zappulla, D.C.1    Cech, T.R.2
  • 12
    • 0033994222 scopus 로고    scopus 로고
    • The Est1 Subunit of Yeast Telomerase Binds the Tlc1 Telomerase RNA
    • Zhou J, Hidaka K, Futcher B. The Est1 Subunit of Yeast Telomerase Binds the Tlc1 Telomerase RNA. Mol Cell Biol 2000; 20:1947-55.
    • (2000) Mol Cell Biol , vol.20 , pp. 1947-1955
    • Zhou, J.1    Hidaka, K.2    Futcher, B.3
  • 14
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases [alpha] and [delta]
    • Diede SJ, Gottschling DE. Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases [alpha] and [delta]. Cell 1999; 99:723-33.
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2
  • 15
    • 0030881688 scopus 로고    scopus 로고
    • Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity
    • Lingner J, Cech TR, Hughes TR, Lundblad V. Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc Nat Acad Sci USA 1997; 94:11190-5.
    • (1997) Proc Nat Acad Sci USA , vol.94 , pp. 11190-11195
    • Lingner, J.1    Cech, T.R.2    Hughes, T.R.3    Lundblad, V.4
  • 16
    • 0033214013 scopus 로고    scopus 로고
    • Est1 and Cdc13 as Comediators of Telomerase Access
    • Evans SK, Lundblad V. Est1 and Cdc13 as Comediators of Telomerase Access. Science 1999; 286:117-20.
    • (1999) Science , vol.286 , pp. 117-120
    • Evans, S.K.1    Lundblad, V.2
  • 17
    • 0037047643 scopus 로고    scopus 로고
    • Est1p As a Cell Cycle-Regulated Activator of Telomere-Bound Telomerase
    • Taggart AKP, Teng S-C, Zakian VA. Est1p As a Cell Cycle-Regulated Activator of Telomere-Bound Telomerase. Science 2002; 297:1023-6.
    • (2002) Science , vol.297 , pp. 1023-1026
    • Taggart, A.K.P.1    Teng, S.-C.2    Zakian, V.A.3
  • 18
    • 34547912131 scopus 로고    scopus 로고
    • Mutual Dependence of Candida albicans Est1p and Est3p in Telomerase Assembly and Activation
    • Hsu M, Yu EY, Singh SM, Lue NF. Mutual Dependence of Candida albicans Est1p and Est3p in Telomerase Assembly and Activation. Eukaryot Cell 2007; 6:1330-8.
    • (2007) Eukaryot Cell , vol.6 , pp. 1330-1338
    • Hsu, M.1    Yu, E.Y.2    Singh, S.M.3    Lue, N.F.4
  • 19
    • 0141525391 scopus 로고    scopus 로고
    • Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
    • Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 2003; 17:2384-95.
    • (2003) Genes Dev , vol.17 , pp. 2384-2395
    • Stellwagen, A.E.1    Haimberger, Z.W.2    Veatch, J.R.3    Gottschling, D.E.4
  • 20
    • 16544390953 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of yeast telomerase by Ku
    • Fisher TS, Taggart AKP, Zakian VA. Cell cycle-dependent regulation of yeast telomerase by Ku. Nat Struct Mol Biol 2004; 11:1198-205.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1198-1205
    • Fisher, T.S.1    Taggart, A.K.P.2    Zakian, V.A.3
  • 21
    • 17944388104 scopus 로고    scopus 로고
    • Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal
    • Jady BE, Bertrand E, Kiss T. Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. J Cell Biol 2004; 164:647-52.
    • (2004) J Cell Biol , vol.164 , pp. 647-652
    • Jady, B.E.1    Bertrand, E.2    Kiss, T.3
  • 22
    • 33644775758 scopus 로고    scopus 로고
    • Human telomerase and Cajal body ribonucleoproteins share a unique specificity of Sm protein association
    • Fu D, Collins K. Human telomerase and Cajal body ribonucleoproteins share a unique specificity of Sm protein association. Genes Dev 2006; 20:531-6.
    • (2006) Genes Dev , vol.20 , pp. 531-536
    • Fu, D.1    Collins, K.2
  • 23
    • 33744799697 scopus 로고    scopus 로고
    • Structure and function of telomerase RNA
    • Theimer CA, Feigon J. Structure and function of telomerase RNA. Curr Opin Struct Biol 2006; 16:307-18.
    • (2006) Curr Opin Struct Biol , vol.16 , pp. 307-318
    • Theimer, C.A.1    Feigon, J.2
  • 24
    • 0032961170 scopus 로고    scopus 로고
    • A Box H/ACA Small Nucleolar RNA-Like Domain at the Human Telomerase RNA 3′ End
    • Mitchell JR, Cheng J, Collins K. A Box H/ACA Small Nucleolar RNA-Like Domain at the Human Telomerase RNA 3′ End. Mol Cell Biol 1999; 19:567-76.
    • (1999) Mol Cell Biol , vol.19 , pp. 567-576
    • Mitchell, J.R.1    Cheng, J.2    Collins, K.3
  • 25
    • 0034459569 scopus 로고    scopus 로고
    • Human H/ACA Small Nucleolar RNPs and Telomerase Share Evolutionarily Conserved Proteins NHP2 and NOP10
    • Pogacic V, Dragon F, Filipowicz W. Human H/ACA Small Nucleolar RNPs and Telomerase Share Evolutionarily Conserved Proteins NHP2 and NOP10. Mol Cell Biol 2000; 20:9028-40.
    • (2000) Mol Cell Biol , vol.20 , pp. 9028-9040
    • Pogacic, V.1    Dragon, F.2    Filipowicz, W.3
  • 26
    • 0038392866 scopus 로고    scopus 로고
    • Distinct Biogenesis Pathways for Human Telomerase RNA and H/ACA Small Nucleolar RNAs
    • Fu D, Collins K. Distinct Biogenesis Pathways for Human Telomerase RNA and H/ACA Small Nucleolar RNAs. Mol Cell 2003; 11:1361-72.
    • (2003) Mol Cell , vol.11 , pp. 1361-1372
    • Fu, D.1    Collins, K.2
  • 28
    • 36749010238 scopus 로고    scopus 로고
    • Purification of Human Telomerase Complexes Identifies Factors Involved in Telomerase Biogenesis and Telomere Length Regulation
    • Fu D, Collins K. Purification of Human Telomerase Complexes Identifies Factors Involved in Telomerase Biogenesis and Telomere Length Regulation. Mol Cell 2007; 28:773-85.
    • (2007) Mol Cell , vol.28 , pp. 773-785
    • Fu, D.1    Collins, K.2
  • 29
    • 32244436688 scopus 로고    scopus 로고
    • Cellular Dynamics of Small RNAs
    • Hopper AK. Cellular Dynamics of Small RNAs. Crit Rev Biochem Mol Biol 2006; 41:3-19.
    • (2006) Crit Rev Biochem Mol Biol , vol.41 , pp. 3-19
    • Hopper, A.K.1
  • 30
    • 33748183271 scopus 로고    scopus 로고
    • Low abundance of telomerase in yeast: Implications for telomerase haploinsufficiency
    • Mozdy AD, Cech TR. Low abundance of telomerase in yeast: Implications for telomerase haploinsufficiency. RNA 2006; 12:1721-37.
    • (2006) RNA , vol.12 , pp. 1721-1737
    • Mozdy, A.D.1    Cech, T.R.2
  • 31
    • 0036333825 scopus 로고    scopus 로고
    • Biogenesis of Yeast Telomerase Depends on the Importin Mtr10
    • Ferrezuelo F, Steiner B, Aldea M, Futcher B. Biogenesis of Yeast Telomerase Depends on the Importin Mtr10. Mol Cell Biol 2002; 22:6046-55.
    • (2002) Mol Cell Biol , vol.22 , pp. 6046-6055
    • Ferrezuelo, F.1    Steiner, B.2    Aldea, M.3    Futcher, B.4
  • 32
    • 0036023953 scopus 로고    scopus 로고
    • Intracellular trafficking of yeast telomerase components
    • Teixeira TM, Förstemann K, Gasser SM, Lingner J. Intracellular trafficking of yeast telomerase components. EMBO R 2002; 3:652-9.
    • EMBO , vol.R 2002 , Issue.3 , pp. 652-659
    • Teixeira, T.M.1    Förstemann, K.2    Gasser, S.M.3    Lingner, J.4
  • 33
    • 40949127352 scopus 로고    scopus 로고
    • TLC1 RNA nucleocytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres
    • Gallardo F, Olivier C, Dandjinou AT, Wellinger RJ, Chartrand P. TLC1 RNA nucleocytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres. The EMBO J 2008; 27:748-57.
    • (2008) The EMBO J , vol.27 , pp. 748-757
    • Gallardo, F.1    Olivier, C.2    Dandjinou, A.T.3    Wellinger, R.J.4    Chartrand, P.5
  • 34
    • 33847187076 scopus 로고    scopus 로고
    • Non-coding RNAs: Lessons from the small nuclear and small nucleolar RNAs
    • Matera AG, Terns RM, Terns MP. Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs. Nat Rev Mol Cell Biol 2007; 8:209-20.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 209-220
    • Matera, A.G.1    Terns, R.M.2    Terns, M.P.3
  • 35
    • 0042594424 scopus 로고    scopus 로고
    • Olson BL and Siliciano A diverse set of nuclear RNAs transfer between nuclei of yeast heterokaryons. Yeast (Chichester, England) 2003; 20:893-903.
    • Olson BL and Siliciano PG. A diverse set of nuclear RNAs transfer between nuclei of yeast heterokaryons. Yeast (Chichester, England) 2003; 20:893-903.
  • 36
    • 0036238278 scopus 로고    scopus 로고
    • Hypermethylation of the Cap Structure of Both Yeast snRNAs and snoRNAs Requires a Conserved Methyltransferase that Is Localized to the Nucleolus
    • Mouaikel J, Verheggen C, Bertrand E, Tazi J, Bordonne R. Hypermethylation of the Cap Structure of Both Yeast snRNAs and snoRNAs Requires a Conserved Methyltransferase that Is Localized to the Nucleolus. Mol Cell 2002; 9:891-901.
    • (2002) Mol Cell , vol.9 , pp. 891-901
    • Mouaikel, J.1    Verheggen, C.2    Bertrand, E.3    Tazi, J.4    Bordonne, R.5
  • 37
    • 17144404877 scopus 로고    scopus 로고
    • Comparative Genomics, Evolution and Origins of the Nuclear Envelope and Nuclear Pore Complex
    • Mans B, Anantharaman V, Aravind L, Koonin EV. Comparative Genomics, Evolution and Origins of the Nuclear Envelope and Nuclear Pore Complex. Cell cycle 2004; 3:1612-37.
    • (2004) Cell cycle , vol.3 , pp. 1612-1637
    • Mans, B.1    Anantharaman, V.2    Aravind, L.3    Koonin, E.V.4
  • 38
    • 33746850081 scopus 로고    scopus 로고
    • Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae
    • Osterhage JL, Talley JM, Friedman KL. Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae. Nat Struct Mol Biol 2006; 13:720-8.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 720-728
    • Osterhage, J.L.1    Talley, J.M.2    Friedman, K.L.3
  • 40
    • 33644927702 scopus 로고    scopus 로고
    • Pumping RNA: Nuclear bodybuilding along the RNP pipeline
    • Matera AG, Shpargel KB. Pumping RNA: nuclear bodybuilding along the RNP pipeline. Curr Opin Cell Biol 2006; 18:317-24.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 317-324
    • Matera, A.G.1    Shpargel, K.B.2
  • 41
    • 34748876539 scopus 로고    scopus 로고
    • Human Telomerase RNA Accumulation in Cajal Bodies Facilitates Telomerase Recruitment to Telomeres and Telomere Elongation
    • Cristofari G, Adolf E, Reichenbach P, Sikora K, Terns RM, Terns MP, Lingner J. Human Telomerase RNA Accumulation in Cajal Bodies Facilitates Telomerase Recruitment to Telomeres and Telomere Elongation. Mol Cell 2007; 27:882-9.
    • (2007) Mol Cell , vol.27 , pp. 882-889
    • Cristofari, G.1    Adolf, E.2    Reichenbach, P.3    Sikora, K.4    Terns, R.M.5    Terns, M.P.6    Lingner, J.7
  • 42
    • 38349087532 scopus 로고    scopus 로고
    • Characterization of a Short Isoform of Human Tgs1 Hypermethylase Associating with Small Nucleolar Ribonucleoprotein Core Proteins and Produced by Limited Proteolytic Processing
    • Girard C, Verheggen C, Neel H, Cammas A, Vagner S, Soret J, Bertrand E, Bordonne R. Characterization of a Short Isoform of Human Tgs1 Hypermethylase Associating with Small Nucleolar Ribonucleoprotein Core Proteins and Produced by Limited Proteolytic Processing. J Biol Chem 2008; 283:2060-9.
    • (2008) J Biol Chem , vol.283 , pp. 2060-2069
    • Girard, C.1    Verheggen, C.2    Neel, H.3    Cammas, A.4    Vagner, S.5    Soret, J.6    Bertrand, E.7    Bordonne, R.8
  • 43
    • 0036711651 scopus 로고    scopus 로고
    • Subnuclear shuttling of human telomerase induced by transformation and DNA damage
    • Wong JMY, Kusdra L, Collins K. Subnuclear shuttling of human telomerase induced by transformation and DNA damage. Nat Cell Biol 2002; 4:731-6.
    • (2002) Nat Cell Biol , vol.4 , pp. 731-736
    • Wong, J.M.Y.1    Kusdra, L.2    Collins, K.3
  • 44
    • 0036311278 scopus 로고    scopus 로고
    • Nucleolar Localization of hTERT Protein Is Associated with Telomerase Function
    • Yang Y, Chen Y, Zhang C, Huang H, Weissman SM. Nucleolar Localization of hTERT Protein Is Associated with Telomerase Function. Exp Cell Res 2002; 277:201-9.
    • (2002) Exp Cell Res , vol.277 , pp. 201-209
    • Yang, Y.1    Chen, Y.2    Zhang, C.3    Huang, H.4    Weissman, S.M.5
  • 46
    • 31944436260 scopus 로고    scopus 로고
    • Cell Cycle-dependent Recruitment of Telomerase RNA and Cajal Bodies to Human Telomeres
    • Jady BE, Richard P, Bertrand E, Kiss T. Cell Cycle-dependent Recruitment of Telomerase RNA and Cajal Bodies to Human Telomeres. Mol Biol Cell 2006; 17:944-54.
    • (2006) Mol Biol Cell , vol.17 , pp. 944-954
    • Jady, B.E.1    Richard, P.2    Bertrand, E.3    Kiss, T.4
  • 47
    • 2042534735 scopus 로고    scopus 로고
    • Telomere Length Homeostasis Is Achieved via a Switch between Telomerase-Extendible and -Nonextendible States
    • Teixeira MT, Arneric M, Sperisen P, Lingner J. Telomere Length Homeostasis Is Achieved via a Switch between Telomerase-Extendible and -Nonextendible States. Cell 2004; 117:323-35.
    • (2004) Cell , vol.117 , pp. 323-335
    • Teixeira, M.T.1    Arneric, M.2    Sperisen, P.3    Lingner, J.4
  • 48
    • 0030886553 scopus 로고    scopus 로고
    • Lack of cell cycle regulation of telomerase activity in human cells
    • Holt SE, Aisner DL, Shay JW, Wright WE. Lack of cell cycle regulation of telomerase activity in human cells. Proc Natl Acad Sci USA 1997; 94:10687-92.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10687-10692
    • Holt, S.E.1    Aisner, D.L.2    Shay, J.W.3    Wright, W.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.