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Volumn 286, Issue 5 30-5, 2004, Pages

Pertussis toxin activates L-arginine uptake in pulmonary endothelial cells through downregulation of PKC-α activity

Author keywords

Cationic amino acid transporter; Caveolae; G proteins; Protein kinase C ; Regulation

Indexed keywords

ADENYLATE CYCLASE; AMINO ACID TRANSPORTER; ARGININE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; NITRIC OXIDE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ZETA;

EID: 1942452756     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00236.2003     Document Type: Article
Times cited : (16)

References (38)
  • 1
    • 0024370460 scopus 로고
    • A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
    • Albritton LM, Tseng L, Scadden D, and Cunningham JM. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57: 659-666, 1989.
    • (1989) Cell , vol.57 , pp. 659-666
    • Albritton, L.M.1    Tseng, L.2    Scadden, D.3    Cunningham, J.M.4
  • 2
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthase: Structure, function and inhibition
    • Alderton WK, Cooper CE, and Knowles RG. Nitric oxide synthase: structure, function and inhibition. Biochem J 357: 593-615, 2001.
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 3
    • 0028827584 scopus 로고
    • Hypoxia inhibits L-arginine uptake by pulmonary artery endothelial cells
    • Block ER, Herrera H, and Couch M. Hypoxia inhibits L-arginine uptake by pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 269: L574-L580, 1995.
    • (1995) Am J Physiol Lung Cell Mol Physiol , vol.269
    • Block, E.R.1    Herrera, H.2    Couch, M.3
  • 4
    • 0031877073 scopus 로고    scopus 로고
    • Protein kinase C regulates nutrient uptake and growth in hepatoma cells
    • Bode BP, Reuter N, Conroy JL, and Souba WW. Protein kinase C regulates nutrient uptake and growth in hepatoma cells. Surgery 124: 260-267, 1998.
    • (1998) Surgery , vol.124 , pp. 260-267
    • Bode, B.P.1    Reuter, N.2    Conroy, J.L.3    Souba, W.W.4
  • 5
    • 0025748140 scopus 로고
    • Bradykinin and ATP timulate L-arginine uptake and nitric oxide release in vascular endothelial cells
    • Bogle RG, Coade SB, Moncada S, Pearson JD, and Mann GE. Bradykinin and ATP timulate L-arginine uptake and nitric oxide release in vascular endothelial cells. Biochem Biophys Res Commun 180: 926-932, 1991.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 926-932
    • Bogle, R.G.1    Coade, S.B.2    Moncada, S.3    Pearson, J.D.4    Mann, G.E.5
  • 6
    • 0031866371 scopus 로고    scopus 로고
    • Pertussis toxin modification of PC12 cell inhibits a protein phosphatase 2A-like phosphatase
    • Chen F, Ngoc-Diep V, and Wagner PD. Pertussis toxin modification of PC12 cell inhibits a protein phosphatase 2A-like phosphatase. J Neurochem 71: 248-257, 1998.
    • (1998) J Neurochem , vol.71 , pp. 248-257
    • Chen, F.1    Ngoc-Diep, V.2    Wagner, P.D.3
  • 7
    • 0031916983 scopus 로고    scopus 로고
    • Transporters for cationic amino acids in animal cells: Discovery, structure, and function
    • Deves R and Boyd CAR. Transporters for cationic amino acids in animal cells: discovery, structure, and function. Physiol Rev 78: 487-545, 1998.
    • (1998) Physiol Rev , vol.78 , pp. 487-545
    • Deves, R.1    Boyd, C.A.R.2
  • 10
    • 0035079905 scopus 로고    scopus 로고
    • The transport activity of human cationic amino acid transporter hCAT-1 is down regulated by activation of protein kinase C
    • Graf P, Forstermann U, and Closs EI. The transport activity of human cationic amino acid transporter hCAT-1 is down regulated by activation of protein kinase C. Br J Pharmacol 132: 1193-1200, 2001.
    • (2001) Br J Pharmacol , vol.132 , pp. 1193-1200
    • Graf, P.1    Forstermann, U.2    Closs, E.I.3
  • 11
    • 0027309122 scopus 로고
    • Characterization of L-arginine transport by pulmonary artery endothelial cells
    • Green B, Pacitti AJ, and Souba WW. Characterization of L-arginine transport by pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 264: L351-L356, 1993.
    • (1993) Am J Physiol Lung Cell Mol Physiol , vol.264
    • Green, B.1    Pacitti, A.J.2    Souba, W.W.3
  • 12
    • 0037081491 scopus 로고    scopus 로고
    • Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells
    • Hardy TA and May JM. Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells. Free Radic Biol Med 32: 122-131, 2002.
    • (2002) Free Radic Biol Med , vol.32 , pp. 122-131
    • Hardy, T.A.1    May, J.M.2
  • 13
    • 0027535167 scopus 로고
    • Phorbol esters induce nitric oxide synthase and increase arginine influx in cultured peritoneal macrophages
    • Hortelano S, Genaro MA, and Bosca L. Phorbol esters induce nitric oxide synthase and increase arginine influx in cultured peritoneal macrophages. FEBS Lett 320: 135-139, 1993.
    • (1993) FEBS Lett , vol.320 , pp. 135-139
    • Hortelano, S.1    Genaro, M.A.2    Bosca, L.3
  • 14
    • 0033921371 scopus 로고    scopus 로고
    • Critical dependence of the NO-mediated component of cyclic AMP-induced vasorelaxation on extracellular L-arginine in pulmonary arteries of the rat
    • Hucks D and Ward JPT. Critical dependence of the NO-mediated component of cyclic AMP-induced vasorelaxation on extracellular L-arginine in pulmonary arteries of the rat. Br J Pharmacol 130: 997-1004, 2000.
    • (2000) Br J Pharmacol , vol.130 , pp. 997-1004
    • Hucks, D.1    Ward, J.P.T.2
  • 15
    • 0034672204 scopus 로고    scopus 로고
    • Determination and bioimaging method for nitric oxide in biological specimens by diaminofluorescein fluorometry
    • Itoh Y, Hai Ma F, Hoshi H, Oka M, Noda K, Ukai Y, Kojima H, Nagano T, and Toda N. Determination and bioimaging method for nitric oxide in biological specimens by diaminofluorescein fluorometry. Anal Biochem 287: 203-209, 2000.
    • (2000) Anal Biochem , vol.287 , pp. 203-209
    • Itoh, Y.1    Hai Ma, F.2    Hoshi, H.3    Oka, M.4    Noda, K.5    Ukai, Y.6    Kojima, H.7    Nagano, T.8    Toda, N.9
  • 16
    • 0026634286 scopus 로고
    • Pertussis toxin and target eukaryotic cells: Binding, entry, and activation
    • Kaslow HR and Burns DL. Pertussis toxin and target eukaryotic cells: binding, entry, and activation. FASEB J 6: 2684-2690, 1992.
    • (1992) FASEB J , vol.6 , pp. 2684-2690
    • Kaslow, H.R.1    Burns, D.L.2
  • 17
    • 0029081954 scopus 로고
    • Pertussis toxin specifically inhibits growth cone guidance by a mechanism independent of direct G protein inactivation
    • Kindt RM and Lander AD. Pertussis toxin specifically inhibits growth cone guidance by a mechanism independent of direct G protein inactivation. Neuron 15: 79-88, 1995.
    • (1995) Neuron , vol.15 , pp. 79-88
    • Kindt, R.M.1    Lander, A.D.2
  • 18
    • 0037834879 scopus 로고    scopus 로고
    • Classical isoforms of PKC as regulators of CAT-1 transporter activity in pulmonary artery endothelial cells
    • Krotova KY, Zharikov SI, and Block ER. Classical isoforms of PKC as regulators of CAT-1 transporter activity in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 284: L1037-L1044, 2003.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284
    • Krotova, K.Y.1    Zharikov, S.I.2    Block, E.R.3
  • 20
    • 0031452440 scopus 로고    scopus 로고
    • A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric oxide synthase may explain the "arginine paradox"
    • McDonald KK, Zharikov S, Block ER, and Kilberg MS. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric oxide synthase may explain the "arginine paradox." J Biol Chem 272: 31213-31216, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 31213-31216
    • McDonald, K.K.1    Zharikov, S.2    Block, E.R.3    Kilberg, M.S.4
  • 21
    • 0024465923 scopus 로고
    • Cholera toxin treatment produces down-regulation of the alpha-subunit of the stimulatory quinine-nucleotide-binding protein
    • Milligan G, Unson CG, and Wakelam MJ. Cholera toxin treatment produces down-regulation of the alpha-subunit of the stimulatory quinine-nucleotide-binding protein. Biochem J 262: 643-649, 1989.
    • (1989) Biochem J , vol.262 , pp. 643-649
    • Milligan, G.1    Unson, C.G.2    Wakelam, M.J.3
  • 23
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer R, and Higgs ER. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43: 109-142, 1991.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.2    Higgs, E.R.3
  • 25
    • 0036211981 scopus 로고    scopus 로고
    • RhoA- and RhoD-dependent regulatory switch of Gα subunit signaling by PAR-1 receptors in cellular invasion
    • Nguyen QD, Faivre S, Bruyneel E, Rivat C, Seto M, Endo T, Mareel M, Emami S, and Gespach C. RhoA- and RhoD-dependent regulatory switch of Gα subunit signaling by PAR-1 receptors in cellular invasion. FASEB J 16: 565-576, 2002.
    • (2002) FASEB J , vol.16 , pp. 565-576
    • Nguyen, Q.D.1    Faivre, S.2    Bruyneel, E.3    Rivat, C.4    Seto, M.5    Endo, T.6    Mareel, M.7    Emami, S.8    Gespach, C.9
  • 26
    • 0029007785 scopus 로고
    • TNF-stimulated arginine transport by human vascular endothelium requires activation of protein kinase C
    • Pan M, Wasa M, Lind DS, Geltler J, Abbot W, and Souba WW. TNF-stimulated arginine transport by human vascular endothelium requires activation of protein kinase C. Ann Surg 221: 590-601, 1995.
    • (1995) Ann Surg , vol.221 , pp. 590-601
    • Pan, M.1    Wasa, M.2    Lind, D.S.3    Geltler, J.4    Abbot, W.5    Souba, W.W.6
  • 28
    • 0033556208 scopus 로고    scopus 로고
    • Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide
    • Posch K, Schmidt K, and Graier WF. Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide. Life Sci 64: 63-67, 1999.
    • (1999) Life Sci , vol.64 , pp. 63-67
    • Posch, K.1    Schmidt, K.2    Graier, W.F.3
  • 29
    • 0032530551 scopus 로고    scopus 로고
    • Activation of L-arginine transport by protein kinase C in rabbit, rat and mouse alveolar macrophages
    • Racke K, Hey C, Mossner J, Hammermann R, Stichnote C, and Wessler I. Activation of L-arginine transport by protein kinase C in rabbit, rat and mouse alveolar macrophages. J Physiol 511: 813-825, 1998.
    • (1998) J Physiol , vol.511 , pp. 813-825
    • Racke, K.1    Hey, C.2    Mossner, J.3    Hammermann, R.4    Stichnote, C.5    Wessler, I.6
  • 30
    • 0033553417 scopus 로고    scopus 로고
    • Activated protein kinase C isoforms target to cardiomyocyte caveolae: Stimulation of local protein phosphorylation
    • Rybin VO, Xu X, and Steinberg SF. Activated protein kinase C isoforms target to cardiomyocyte caveolae: stimulation of local protein phosphorylation. Circ Res 84:980-988, 1999.
    • (1999) Circ Res , vol.84 , pp. 980-988
    • Rybin, V.O.1    Xu, X.2    Steinberg, S.F.3
  • 31
    • 0023610240 scopus 로고
    • Human T lymphocyte mitogenesis in response to the β-oligomer of pertussis toxin is associated with an early elevation of cytosolic calcium concentrations
    • Sternad CF and Carchman RA. Human T lymphocyte mitogenesis in response to the β-oligomer of pertussis toxin is associated with an early elevation of cytosolic calcium concentrations. FEBS Lett 225: 16-20, 1987.
    • (1987) FEBS Lett , vol.225 , pp. 16-20
    • Sternad, C.F.1    Carchman, R.A.2
  • 34
    • 0020520658 scopus 로고
    • A role of the β-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells
    • Tamura M, Nogimori K, Yajima M, Ase K, and Ui M. A role of the β-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells. J Biol Chem 258: 6756-6761, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 6756-6761
    • Tamura, M.1    Nogimori, K.2    Yajima, M.3    Ase, K.4    Ui, M.5
  • 35
    • 0024495612 scopus 로고
    • Pertussis toxin activates protein kinase C and tyrosine protein kinase in the human T cell line Jurkat
    • Thom RE and Casnellie JE. Pertussis toxin activates protein kinase C and tyrosine protein kinase in the human T cell line Jurkat. FEBS Lett 244: 181-184, 1989.
    • (1989) FEBS Lett , vol.244 , pp. 181-184
    • Thom, R.E.1    Casnellie, J.E.2
  • 36
    • 0031577278 scopus 로고    scopus 로고
    • Signaling mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: Role of tyrosine phosphorylation
    • Wong WS and Luk JM. Signaling mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of tyrosine phosphorylation. Biochem Biophys Res Commun 236: 479-483, 1997.
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 479-483
    • Wong, W.S.1    Luk, J.M.2
  • 38
    • 0032472847 scopus 로고    scopus 로고
    • Characterization of L-arginine uptake by plasma membrane vesicles isolated from cultured pulmonary artery endothelial cells
    • Zharikov SI and Block ER. Characterization of L-arginine uptake by plasma membrane vesicles isolated from cultured pulmonary artery endothelial cells. Biochim Biophys Acta 1369: 173-183, 1998.
    • (1998) Biochim Biophys Acta , vol.1369 , pp. 173-183
    • Zharikov, S.I.1    Block, E.R.2


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