-
2
-
-
33749356167
-
Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration
-
Cheung RT, Tipoe GL, Tam S, Ma ES, Zou LY, Chan PS. Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration. J Pineal Res 2006 41 : 337 343.
-
(2006)
J Pineal Res
, vol.41
, pp. 337-343
-
-
Cheung, R.T.1
Tipoe, G.L.2
Tam, S.3
Ma, E.S.4
Zou, L.Y.5
Chan, P.S.6
-
3
-
-
0037378182
-
The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion
-
Cheung RT. The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion. J Pineal Res 2003 34 : 153 160.
-
(2003)
J Pineal Res
, vol.34
, pp. 153-160
-
-
Cheung, R.T.1
-
4
-
-
33947592217
-
Melatonin and its metabolites: New findings regarding their production and their radical scavenging actions
-
Reiter RJ, Tan DX, Terron MP, Flores LJ, Czarnocki Z. Melatonin and its metabolites: new findings regarding their production and their radical scavenging actions. Acta Biochim Pol 2007 54 : 1 9.
-
(2007)
Acta Biochim Pol
, vol.54
, pp. 1-9
-
-
Reiter, R.J.1
Tan, D.X.2
Terron, M.P.3
Flores, L.J.4
Czarnocki, Z.5
-
5
-
-
33845536018
-
One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
-
Tan DX, Manchester LC, Terron MP et al. One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res 2007 42 : 28 42.
-
(2007)
J Pineal Res
, vol.42
, pp. 28-42
-
-
Tan, D.X.1
Manchester, L.C.2
Terron, M.P.3
-
6
-
-
12744273107
-
When melatonin gets on your nerves: Its beneficial actions in experimental models of stroke
-
Reiter RJ, Tan DX, Leon J, Kilic U, Kilic E. When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. Exp Biol Med (Maywood) 2005 230 : 104 117.
-
(2005)
Exp Biol Med (Maywood)
, vol.230
, pp. 104-117
-
-
Reiter, R.J.1
Tan, D.X.2
Leon, J.3
Kilic, U.4
Kilic, E.5
-
7
-
-
33746531630
-
Melatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood-brain barrier permeability after transient focal cerebral ischemia in mice
-
Chen HY, Chen TY, Lee MY et al. Melatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood-brain barrier permeability after transient focal cerebral ischemia in mice. J Pineal Res 2006 41 : 175 182.
-
(2006)
J Pineal Res
, vol.41
, pp. 175-182
-
-
Chen, H.Y.1
Chen, T.Y.2
Lee, M.Y.3
-
8
-
-
33644772082
-
Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice
-
Chen TY, Lee MY, Chen HY et al. Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice. J Pineal Res 2006 40 : 242 250.
-
(2006)
J Pineal Res
, vol.40
, pp. 242-250
-
-
Chen, T.Y.1
Lee, M.Y.2
Chen, H.Y.3
-
9
-
-
12344307153
-
Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice
-
Kilic U, Kilic E, Reiter RJ, Bassetti CL, Hermann DM. Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res 2005 38 : 67 71.
-
(2005)
J Pineal Res
, vol.38
, pp. 67-71
-
-
Kilic, U.1
Kilic, E.2
Reiter, R.J.3
Bassetti, C.L.4
Hermann, D.M.5
-
10
-
-
33847654606
-
Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats
-
Lee MY, Kuan YH, Chen HY et al. Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats. J Pineal Res 2007 42 : 297 309.
-
(2007)
J Pineal Res
, vol.42
, pp. 297-309
-
-
Lee, M.Y.1
Kuan, Y.H.2
Chen, H.Y.3
-
11
-
-
0037373015
-
Melatonin reduces nitric oxide level during ischemia but not blood-brain barrier breakdown during reperfusion in a rat middle cerebral artery occlusion stroke model
-
Pei Z, Fung PC, Cheung RT. Melatonin reduces nitric oxide level during ischemia but not blood-brain barrier breakdown during reperfusion in a rat middle cerebral artery occlusion stroke model. J Pineal Res 2003 34 : 110 118.
-
(2003)
J Pineal Res
, vol.34
, pp. 110-118
-
-
Pei, Z.1
Fung, P.C.2
Cheung, R.T.3
-
12
-
-
0036229548
-
Pretreatment with melatonin reduces volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model
-
Pei Z, Pang SF, Cheung RT. Pretreatment with melatonin reduces volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model. J Pineal Res 2002 32 : 168 172.
-
(2002)
J Pineal Res
, vol.32
, pp. 168-172
-
-
Pei, Z.1
Pang, S.F.2
Cheung, R.T.3
-
13
-
-
33750546285
-
Hypoxia-induced astrocytic reaction and increased vascular permeability in the rat cerebellum
-
Kaur C, Sivakumar V, Zhang Y, Ling EA. Hypoxia-induced astrocytic reaction and increased vascular permeability in the rat cerebellum. Glia 2006 54 : 826 839.
-
(2006)
Glia
, vol.54
, pp. 826-839
-
-
Kaur, C.1
Sivakumar, V.2
Zhang, Y.3
Ling, E.A.4
-
14
-
-
0037147074
-
Melatonin reduces cerebral edema formation caused by transient forebrain ischemia in rats
-
Kondoh T, Uneyama H, Nishino H, Torii K. Melatonin reduces cerebral edema formation caused by transient forebrain ischemia in rats. Life Sci 2002 72 : 583 590.
-
(2002)
Life Sci
, vol.72
, pp. 583-590
-
-
Kondoh, T.1
Uneyama, H.2
Nishino, H.3
Torii, K.4
-
15
-
-
1642440106
-
Melatonin suppresses cerebral edema caused by middle cerebral artery occlusion/reperfusion in rats assessed by magnetic resonance imaging
-
Torii K, Uneyama H, Nishino H, Kondoh T. Melatonin suppresses cerebral edema caused by middle cerebral artery occlusion/reperfusion in rats assessed by magnetic resonance imaging. J Pineal Res 2004 36 : 18 24.
-
(2004)
J Pineal Res
, vol.36
, pp. 18-24
-
-
Torii, K.1
Uneyama, H.2
Nishino, H.3
Kondoh, T.4
-
16
-
-
33845529120
-
The potential of melatonin in reducing morbidity-mortality after craniocerebral trauma
-
Maldonado MD, Murillo-Cabezas F, Terron MP et al. The potential of melatonin in reducing morbidity-mortality after craniocerebral trauma. J Pineal Res 2007 42 : 1 11.
-
(2007)
J Pineal Res
, vol.42
, pp. 1-11
-
-
Maldonado, M.D.1
Murillo-Cabezas, F.2
Terron, M.P.3
-
17
-
-
1342268351
-
Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1
-
Beni SM, Kohen R, Reiter RJ, Tan DX, Shohami E. Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1. FASEB J 2004 18 : 149 151.
-
(2004)
FASEB J
, vol.18
, pp. 149-151
-
-
Beni, S.M.1
Kohen, R.2
Reiter, R.J.3
Tan, D.X.4
Shohami, E.5
-
18
-
-
22144489589
-
Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats
-
Ozdemir D, Uysal N, Gonenc S et al. Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats. Physiol Res 2005 54 : 631 637.
-
(2005)
Physiol Res
, vol.54
, pp. 631-637
-
-
Ozdemir, D.1
Uysal, N.2
Gonenc, S.3
-
19
-
-
39149098768
-
Melatonin decreases mortality following severe subarachnoid hemorrhage
-
Ayer RE, Sugawara T, Chen W, Tong W, Zhang JH. Melatonin decreases mortality following severe subarachnoid hemorrhage. J Pineal Res 2008 44 : 197 204.
-
(2008)
J Pineal Res
, vol.44
, pp. 197-204
-
-
Ayer, R.E.1
Sugawara, T.2
Chen, W.3
Tong, W.4
Zhang, J.H.5
-
20
-
-
33644908054
-
Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus
-
Lee SH, Chun W, Kong PJ et al. Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus. J Pineal Res 2006 40 : 79 85.
-
(2006)
J Pineal Res
, vol.40
, pp. 79-85
-
-
Lee, S.H.1
Chun, W.2
Kong, P.J.3
-
21
-
-
27644489007
-
Melatonin and Parkinson's disease
-
Mayo JC, Sainz RM, Tan DX, Antolín I, Rodríguez C, Reiter RJ. Melatonin and Parkinson's disease. Endocrine 2005 27 : 169 178.
-
(2005)
Endocrine
, vol.27
, pp. 169-178
-
-
Mayo, J.C.1
Sainz, R.M.2
Tan, D.X.3
Antolín, I.4
Rodríguez, C.5
Reiter, R.J.6
-
22
-
-
33644809553
-
Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease
-
Alvira D, Tajes M, Verdaguer E et al. Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease. J Pineal Res 2006 40 : 251 258.
-
(2006)
J Pineal Res
, vol.40
, pp. 251-258
-
-
Alvira, D.1
Tajes, M.2
Verdaguer, E.3
-
23
-
-
30144433689
-
Role of melatonin in Alzheimer-like neurodegeneration
-
Wang JZ, Wang ZF. Role of melatonin in Alzheimer-like neurodegeneration. Acta Pharmacol Sin 2006 27 : 41 49.
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 41-49
-
-
Wang, J.Z.1
Wang, Z.F.2
-
24
-
-
27744510015
-
Role of melatonin in neurodegenerative diseases
-
Srinivasan V, Pandi-Perumal SR, Maestroni GJ, Esquifino AI, Hardeland R, Cardinali DP. Role of melatonin in neurodegenerative diseases. Neurotox Res 2005 7 : 293 318.
-
(2005)
Neurotox Res
, vol.7
, pp. 293-318
-
-
Srinivasan, V.1
Pandi-Perumal, S.R.2
Maestroni, G.J.3
Esquifino, A.I.4
Hardeland, R.5
Cardinali, D.P.6
-
25
-
-
0026842182
-
Postoperative complications in neurosurgery
-
Fasano VA, Penna G. Postoperative complications in neurosurgery. Minerva Anestesiol 1992 58 : 15 21.
-
(1992)
Minerva Anestesiol
, vol.58
, pp. 15-21
-
-
Fasano, V.A.1
Penna, G.2
-
27
-
-
0026843916
-
Postoperative cerebral edema. Physiopathology of the edema and medical therapy
-
Tommasino C. Postoperative cerebral edema. Physiopathology of the edema and medical therapy. Minerva Anestesiol 1992 58 : 35 42.
-
(1992)
Minerva Anestesiol
, vol.58
, pp. 35-42
-
-
Tommasino, C.1
-
28
-
-
34047203302
-
Inhibition of Src tyrosine kinase and effect on outcomes in a new in vivo model of surgically induced brain injury
-
Jadhav V, Matchett G, Hsu FP, Zhang JH. Inhibition of Src tyrosine kinase and effect on outcomes in a new in vivo model of surgically induced brain injury. J Neurosurg 2007 106 : 680 686.
-
(2007)
J Neurosurg
, vol.106
, pp. 680-686
-
-
Jadhav, V.1
Matchett, G.2
Hsu, F.P.3
Zhang, J.H.4
-
30
-
-
33847214852
-
NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury
-
Lo W, Bravo T, Jadhav V, Titova E, Zhang JH, Tang J. NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury. Neurosci Lett 2007 414 : 228 232.
-
(2007)
Neurosci Lett
, vol.414
, pp. 228-232
-
-
Lo, W.1
Bravo, T.2
Jadhav, V.3
Titova, E.4
Zhang, J.H.5
Tang, J.6
-
31
-
-
37349057492
-
Matrix metalloproteinase inhibition attenuates brain edema in an in vivo model of surgically-induced brain injury
-
Yamaguchi M, Jadhav V, Obenaus A, Colohan A, Zhang JH. Matrix metalloproteinase inhibition attenuates brain edema in an in vivo model of surgically-induced brain injury. Neurosurgery 2007 61 : 1067 1075.
-
(2007)
Neurosurgery
, vol.61
, pp. 1067-1075
-
-
Yamaguchi, M.1
Jadhav, V.2
Obenaus, A.3
Colohan, A.4
Zhang, J.H.5
-
32
-
-
32144461723
-
Stroke and neurovascular protection
-
Del Zoppo GJ. Stroke and neurovascular protection. N Engl J Med 2006 354 : 553 555.
-
(2006)
N Engl J Med
, vol.354
, pp. 553-555
-
-
Del Zoppo, G.J.1
-
33
-
-
2542551340
-
Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia
-
Gursory-Ozdemir Y, Can A, Dalkara T. Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia. Stroke 2004 35 : 1449 1453.
-
(2004)
Stroke
, vol.35
, pp. 1449-1453
-
-
Gursory-Ozdemir, Y.1
Can, A.2
Dalkara, T.3
-
35
-
-
0035989226
-
Brain edema after intracerebral hemorrhage: The effects of systemic complement depletion
-
Xi G, Hua Y, Keep RF, Younger JG, Hoff JT. Brain edema after intracerebral hemorrhage: the effects of systemic complement depletion. Acta Neurochir Suppl 2002 81 : 253 256.
-
(2002)
Acta Neurochir Suppl
, vol.81
, pp. 253-256
-
-
Xi, G.1
Hua, Y.2
Keep, R.F.3
Younger, J.G.4
Hoff, J.T.5
-
36
-
-
0036791849
-
Behavioral tests after intracerebral hemorrhage in the rat
-
Hua Y, Schallert T, Keep RF, Wu J, Hoff JT, Xi G. Behavioral tests after intracerebral hemorrhage in the rat. Stroke 2002 33 : 2478 2484.
-
(2002)
Stroke
, vol.33
, pp. 2478-2484
-
-
Hua, Y.1
Schallert, T.2
Keep, R.F.3
Wu, J.4
Hoff, J.T.5
Xi, G.6
-
37
-
-
23744513206
-
A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes
-
Tomas-Zapico C, Coto-Montes A. A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes. J Pineal Res 2005 39 : 99 104.
-
(2005)
J Pineal Res
, vol.39
, pp. 99-104
-
-
Tomas-Zapico, C.1
Coto-Montes, A.2
-
38
-
-
33244492125
-
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain
-
Yon JH, Carter LB, Reiter RJ, Jevtovic-Todorovic V. Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiol Dis 2006 21 : 522 530.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 522-530
-
-
Yon, J.H.1
Carter, L.B.2
Reiter, R.J.3
Jevtovic-Todorovic, V.4
-
39
-
-
32944473624
-
Dose-dependent neuroprotective effects of melatonin on experimental spinal cord injury in rats
-
Gul S, Celik SE, Kalayci M, Tasyurekli M, Cokar N, Bilge T. Dose-dependent neuroprotective effects of melatonin on experimental spinal cord injury in rats. Surg Neurol 2005 64 : 355 361.
-
(2005)
Surg Neurol
, vol.64
, pp. 355-361
-
-
Gul, S.1
Celik, S.E.2
Kalayci, M.3
Tasyurekli, M.4
Cokar, N.5
Bilge, T.6
-
40
-
-
0030778136
-
Sleep-promoting effects of melatonin: At what dose, in whom, under what conditions, and by what mechanisms?
-
Sack RL, Hughes RJ, Edgar DM, Lewy AJ. Sleep-promoting effects of melatonin: at what dose, in whom, under what conditions, and by what mechanisms? Sleep 1997 20 : 908 915.
-
(1997)
Sleep
, vol.20
, pp. 908-915
-
-
Sack, R.L.1
Hughes, R.J.2
Edgar, D.M.3
Lewy, A.J.4
|