Peroxynitrite: Just an oxidative/nitrosative stressor or a physiological regulator as well?

British Journal of Pharmacology

Volumn 148, Issue 1, 2006, Pages 1-3

  Ferdinandy, Péter ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

K ATP; Nitric oxide; Peroxynitrite; Preconditioning; S glutathiolation; S nitrosylation; Stress adaptation; Stress signaling; Superoxide

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ANTIOXIDANT; NITRIC OXIDE; OXIDIZING AGENT; PENICILLAMINE; PEROXYNITRITE; SCAVENGER; SUPEROXIDE;

ADAPTATION; CELL FUNCTION; CELL PROTECTION; CYTOTOXICITY; HUMAN; MEASUREMENT; NITROSATIVE STRESS; NITROSYLATION; NONHUMAN; NOTE; OXIDATIVE STRESS; PHYSIOLOGY; PRECONDITIONING; PRIORITY JOURNAL; PROTECTION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STRESS; VASODILATATION;

ANIMALS; HUMANS; OXIDATIVE STRESS; PEROXYNITROUS ACID; SIGNAL TRANSDUCTION; TYROSINE;

EID: 33646400011     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706693     Document Type: Note

References (37)

1. ADACHI, T., WEISBROD, R.M., PIMENTEL, D.R., YING, J., SHAROV, V.S., SCHONEICH, C. & COHEN, R.A. (2004). S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. Nat. Med., 10, 1200-1207.
2. ALTUG, S., DEMIRYUREK, A.T., KANE, K.A. & KANZIK, I. (2000). Evidence for the involvement of peroxynitrite in ischaemic preconditioning in rat isolated hearts. Br. J. Pharmacol., 130, 125-131.
3. ALVAREZ, B. & RADI, R. (2003). Peroxynitrite reactivity with amino acids and proteins. Amino Acids, 25, 295-311.
4. CERIONI, L., PALOMBA, L., BRUNE, B. & CANTONI, O. (2006). Peroxynitrite-induced mitochondrial translocation of PKCalpha causes U937 cell survival. Biochem. Biophys. Res. Commun., 339, 126-131.
5. CSONKA, C., CSONT, T., ONODY, A. & FERDINANDY, P. (2001). Preconditioning decreases ischemia/reperfusion-induced peroxynitrite formation. Biochem. Biophys. Res. Commun., 285, 1217-1219.
6. DAIBER, A., BACHSCHMID, M., KAVAKLI, C., FREIN, D., WENDT, M., ULLRICH, V. & MUNZEL, T. (2003). A new pitfall in detecting biological end products of nitric oxide-nitration, nitros(yl)ation and nitrite/nitrate artefacts during freezing. Nitric Oxide, 9, 44-52.
7. DENICOLA, A. & RADI, R. (2005). Peroxynitrite and drug-dependent toxicity. Toxicology, 208, 273-288.
8. DIGERNESS, S.B., HARRIS, K.D., KIRKLIN, J.W., URTHALER, F., VIERA, L., BECKMAN, J.S. & DARLEY-USMAR, V. (1999). Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscle. Free Rad. Biol. Med., 27, 1386-1392.
9. EISERICH, J.P., HRISTOVA, M., CROSS, C.E., JONES, A.D., FREEMAN, B.A., HALLIWELL, B. & VAN, D.V. (1998). Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature, 391, 393-397.
10. FERDINANDY, P. & SCHULZ, R. (2001). Peroxynitrite: Toxic or protective in the heart? Circ. Res., 88, e12-e13.
11. FERDINANDY, P. & SCHULZ, R. (2003). Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br. J. Pharmacol., 138, 532-543.
12. FERDINANDY, P., DANIAL, H., AMBRUS, I., ROTHERY, R.A. & SCHULZ, R. (2000). Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ. Res., 87, 241-247.
13. GIRICZ, Z., LALU, M.M., CSONKA, C., BENCSIK, P., SCHULZ, R. & FERDINANDY, P. (2006). Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition. J. Pharmacol. Exp. Ther., 316, 154-161.
14. GRAVES, J.E., KOOY, N.W. & LEWIS, S.J. (2006). L-beta-beta-dimethylcysteine attenuates the haemodynamic responses elicited by systemic injections of peroxynitrite in anaesthetized rats. Br. J. Pharmacol., 148, 7-15 (this issue).
15. GRAVES, J.E., LEWIS, S.J. & KOOY, N.W. (1998). Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols. Am. J. Physiol., 274, H1001-H1008.
16. GRAVES, J.E., LEWIS, S.J. & KOOY, N.W. (2005a). Loss of K+ATP-channel-mediated vasodilation after induction of tachyphylaxis to peroxynitrite. J. Cardiovasc. Pharmacol., 46, 646-652.
17. GRAVES, J.E., LEWIS, S.J. & KOOY, N.W. (2005b). Role of ATP-sensitive K+-channels in hemodynamic effects of peroxynitrite in anesthetized rats. J. Cardiovasc. Pharmacol., 46, 653-659.
18. HEROLD, S. & FAGO, A. (2005). Reactions of peroxynitrite with globin proteins and their possible physiological role. Comp. Biochem. Physiol. A Mol. Integr. Physiol., 142, 124-129.
19. ISHIDA, H., GENKA, C. & NAKAZAWA, H. (1999). Application of authentic peroxynitrite to biological materials. Methods Enzymol., 301, 402-409.
20. JI, Y., AKERBOOM, T.P., SIES, H. & THOMAS, J.A. (1999). S-nitrosylation and S-glutathiolation of protein sulfhydryls by S-nitroso glutathione. Arch. Biochem. Biophys., 362, 67-78.
21. JI, Y., NEVEROVA, I., VAN EYK, J.E. & BENNETT, B.M. (2006). Nitration of tyrosine 92 mediates the activation of rat microsomal glutathione S-transferase by peroxynitrite. J. Biol. Chem., 281, 1986-1991.
22. KLOTZ, L.O., SCHROEDER, P. & SIES, H. (2002). Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways. Free Radic. Biol. Med., 33, 737-743.
23. LEFER, D.J., SCALIA, R., CAMPBELL, B., NOSSULI, T.O., HAYWARD, R., SALAMON, M., GRAYSON, J. & LEFER, A.M. (1997). Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. J. Clin. Invest., 99, 684-691.
24. NOSSULI, T.O., HAYWARD, R., JENSEN, D., SCALIA, R. & LEFER, A.M. (1998). Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury. Am. J. Physiol., 275, H509-H519.
25. NOSSULI, T.O., HAYWARD, R., SCALIA, R. & LEFER, A.M. (1997). Peroxynitrite reduces myocardial infarct size and preserves coronary endothelium after ischemia and reperfusion in cats. Circulation, 96, 2317-2324.
26. OKAMOTO, T., AKAIKE, T., SAWA, T., MIYAMOTO, Y., VAN DER VLIET, A. & MAEDA, H. (2001). Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation. J. Biol. Chem., 276, 29596-29602.
27. PAOLOCCI, N., EKELUND, U.E., ISODA, T., OZAKI, M., VANDEGAER, K., GEORGAKOPOULOS, D., HARRISON, R.W., KASS, D.A. & HARE, J.M. (2000). cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation. Am. J. Physiol. Heart Circ. Physiol., 279, H1982-H1988.
28. RUBBO, H., DARLEY-USMAR, V. & FREEMAN, B.A. (1996). Nitric oxide regulation of tissue free radical injury. Chem. Res. Toxicol., 9, 809-820.
29. SALVEMINI, D., WANG, Z.Q., STERN, M.K., CURRIE, M.G. & MISKO, T.P. (1998). Peroxynitrite decomposition catalysts: novel therapeutics for peroxynitrite-mediated pathology. Proc. Natl. Acad. Sci. U.S.A., 95, 2659-2663.
30. SCHULZ, R., DODGE, K.L., LOPASCHUK, G.D. & CLANACHAN, A.S. (1997). Peroxynitrite impairs cardiac contractile function by decreasing cardiac efficiency. Am. J. Physiol. Heart Circ. Physiol., 272, H1212-H1219.
31. STEFFEN, M., SARKELA, T.M., GYBINA, A.A., STEELE, T.W., TRASSETH, N.J., KUEHL, D. & GIULIVI, C. (2001). Metabolism of S-nitrosoglutathione in intact mitochondria. Biochem. J., 356, 395-402.
32. SZABÓ, C. (1996). The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock, 6, 79-88.
33. TARPEY, M.M. & FRIDOVICH, I. (2001). Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ. Res., 89, 224-236.
34. VAN DER VLIET, A., EISERICH, J.P., O'NEILL, C.A., HALLIWELL, B. & CROSS, C.E. (1995). Tyrosine modification by reactive nitrogen species: a closer look. Arch. Biochem. Biophys., 329, 341-349.
35. VINER, R.I., WILLIAMS, T.D. & SCHONEICH, C. (1999). Peroxynitrite modification of protein thiols: oxidation, nitrosylation, and S-glutathiolation of functionally important cysteine residue(s) in the sarcoplasmic reticulum Ca-ATPase. Biochemistry, 38, 12408-12415.
36. VIRAG, L., SZABO, E., GERGELY, P. & SZABO, C. (2003). Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention. Toxicol. Lett., 140-141, 113-124.
37. WINK, D.A., HANBAUER, I., KRISHNA, M.C., DEGRAFF, W., GAMSON, J. & MITCHELL, J.B. (1993). Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species. Proc. Natl. Acad. Sci. U.S.A., 90, 9813-9817.