Role of CYP epoxygenases in A2AAR-mediated relaxation using A2AAR-null and wild-type mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 5, 2008, Pages

  Nayeem, Mohammed A ^a   Poloyac, Samuel M ^d   Falck, John R ^b   Zeldin, Darryl C ^e   Ledent, Catherine ^c   Ponnoth, Dovenia S ^a   Ansari, Habib R ^a   Mustafa, S Jamal ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Adenosine; Cytochrome P 450s; Dihydroxyeicosatrienoic acids; Epoxyeicosatrienoic acids; Vasoconstriction; Vasodilation

Indexed keywords

14,15 EPOXYEICOSA 5 ENOIC ACID; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2A RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 EPOXYGENASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPOXYICOSATRIENOIC ACID; INDOMETACIN; N NITRO LEVO ARGININE METHYL ESTER; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; ENDOTHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASOCONSTRICTION;

8,11,14-EICOSATRIENOIC ACID; ACETYLCHOLINE; ADENOSINE; ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ALKANE 1-MONOOXYGENASE; AMIDES; AMIDINES; ANIMALS; AORTA; ARACHIDONIC ACID; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; INDOMETHACIN; MALE; MICE; MICE, KNOCKOUT; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PHENETHYLAMINES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIMIDINES; RECEPTOR, ADENOSINE A2A; TANDEM MASS SPECTROMETRY; TRIAZOLES; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 57049160502     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01333.2007     Document Type: Article

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