메뉴 건너뛰기




Volumn 168, Issue 4, 2000, Pages 543-549

Molecular mechanisms controlling nutritive blood flow: Role of cytochrome P450 enzymes

Author keywords

Cerebral blood flow; Cytochrome p450; Functional hypermia; Glutamate; Microcirculation

Indexed keywords

ARACHIDONIC ACID DERIVATIVE; COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 4A; EPOXYICOSATRIENOIC ACID; OXYGENASE; UNCLASSIFIED DRUG;

EID: 0034032372     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2000.00707.x     Document Type: Conference Paper
Times cited : (34)

References (37)
  • 1
    • 33750807720 scopus 로고    scopus 로고
    • Inhibition of brain P450 arachidonic acid epoxygenase decreases baseline cerebral blood flow
    • Alkayed, N.J., Birks, E.K., Hudetz, A.G., Roman, R.J., Henderson, L. & Harder, D.R. 1996a. Inhibition of brain P450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol 27, H1541-H1546.
    • (1996) Am J Physiol , vol.27
    • Alkayed, N.J.1    Birks, E.K.2    Hudetz, A.G.3    Roman, R.J.4    Henderson, L.5    Harder, D.R.6
  • 2
    • 0029930387 scopus 로고    scopus 로고
    • Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes
    • Alkayed, N.J., Narayanan, J., Gebremedhin, D., Medhora, M., Roman, R.J. & Harder, D.H. 1996b. Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. Stroke 5, 971-979.
    • (1996) Stroke , vol.5 , pp. 971-979
    • Alkayed, N.J.1    Narayanan, J.2    Gebremedhin, D.3    Medhora, M.4    Roman, R.J.5    Harder, D.H.6
  • 3
    • 84944486665 scopus 로고
    • On the local reactions of the arterial wall to changes of internal pressure
    • Bayliss, W.M. 1902. On the local reactions of the arterial wall to changes of internal pressure. J Physiol (Lond) 28, 220-231.
    • (1902) J Physiol (Lond) , vol.28 , pp. 220-231
    • Bayliss, W.M.1
  • 4
    • 0011330075 scopus 로고
    • Diacyglyceride lipase: A pathway for arachidonate release from human platelets
    • Bell, R.L., Kennerly, D.A., Stanford, N. & Mjerus, P.W. 1979. Diacyglyceride lipase: a pathway for arachidonate release from human platelets. Proc Natl Acad Sci, USA 3238-3241.
    • (1979) Proc Natl Acad Sci, USA , pp. 3238-3241
    • Bell, R.L.1    Kennerly, D.A.2    Stanford, N.3    Mjerus, P.W.4
  • 5
    • 0013649391 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenase inhibitors block the cerebral blood flow response to N-methyl-D-aspartate in rat striatum
    • in press
    • Bhardwaj, A., Northington, F.J., Carhuapoma, J.R. et al. 2000. Cytochrome P450 epoxygenase inhibitors block the cerebral blood flow response to N-methyl-D-aspartate in rat striatum. Am J Physiol in press.
    • (2000) Am J Physiol
    • Bhardwaj, A.1    Northington, F.J.2    Carhuapoma, J.R.3
  • 6
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
    • Campbell, W.B., Gebremedhin, D., Pratt, P.F. & Harder, D.R. 1996. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 78, 415-423.
    • (1996) Circ Res , vol.78 , pp. 415-423
    • Campbell, W.B.1    Gebremedhin, D.2    Pratt, P.F.3    Harder, D.R.4
  • 7
    • 0026569586 scopus 로고
    • Cytochrome P450 and the arachidonic acid cascade
    • Capdevila, J.H., Falck, J.R. & Estabrook, R.W. 1992. Cytochrome P450 and the arachidonic acid cascade. FASEB J 6, 731-736.
    • (1992) FASEB J , vol.6 , pp. 731-736
    • Capdevila, J.H.1    Falck, J.R.2    Estabrook, R.W.3
  • 8
    • 0032989206 scopus 로고    scopus 로고
    • Pentobarbital-sensitive EDHF comediates ACh-induced arteriolar dilation in the hamster microcirculation
    • De Wit, C., Esser, N., Lehr, H.-A., Boltz, S.-S. & Pohl, U. 1999. Pentobarbital-sensitive EDHF comediates ACh-induced arteriolar dilation in the hamster microcirculation. Am J Physiol 276, H1527-H1534.
    • (1999) Am J Physiol , vol.276
    • De Wit, C.1    Esser, N.2    Lehr, H.-A.3    Boltz, S.-S.4    Pohl, U.5
  • 9
    • 0025869402 scopus 로고
    • Role of phospholipases in generating lipid second messengers in signal transduction
    • Dennis, E.A., Rhee, S.G., Billah, M. & Hannun, Y.A. 1991. Role of phospholipases in generating lipid second messengers in signal transduction. FASEB J 5, 2068-2077.
    • (1991) FASEB J , vol.5 , pp. 2068-2077
    • Dennis, E.A.1    Rhee, S.G.2    Billah, M.3    Hannun, Y.A.4
  • 10
    • 0004156151 scopus 로고
    • Cytochrome P-450: A versatile vehicle of variable veracity
    • M. Nozake (ed.) Academic Press, New York
    • Estabrook, R., Chacos, N., Martin-Wixstron, C. & Capdevila, J. 1982. Cytochrome P-450: A Versatile Vehicle of Variable Veracity. In: M. Nozake (ed.) Oxygenases and Oxygen Metabolism, pp. 371-387. Academic Press, New York.
    • (1982) Oxygenases and Oxygen Metabolism , pp. 371-387
    • Estabrook, R.1    Chacos, N.2    Martin-Wixstron, C.3    Capdevila, J.4
  • 11
    • 0024217265 scopus 로고
    • Cytochrome P-450 metabolism of arachidonic acid: Formation and biological actions of 'epoxygenase'-derived eicosanoids
    • Fitzpatrick, F.A. & Murphy, R.C. 1989. Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of 'epoxygenase'-derived eicosanoids. Pharmacol Rev 40, 229-241.
    • (1989) Pharmacol Rev , vol.40 , pp. 229-241
    • Fitzpatrick, F.A.1    Murphy, R.C.2
  • 12
    • 0031819649 scopus 로고    scopus 로고
    • Bioassay of an endothelium-derived hyperpolarizing factor from bovine coronary arteries; role of cytochrome P450 metabolite
    • Gebremedhin, D., Harder, D.R., Pratt, P.F. & Campbell, W.B. 1998a. Bioassay of an endothelium-derived hyperpolarizing factor from bovine coronary arteries; Role of cytochrome P450 metabolite. J Vasc Res 35, 274-284.
    • (1998) J Vasc Res , vol.35 , pp. 274-284
    • Gebremedhin, D.1    Harder, D.R.2    Pratt, P.F.3    Campbell, W.B.4
  • 14
    • 0026758963 scopus 로고
    • Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle
    • Gebremedhin, D., Ma, Y.-H., Falck, J.R., Roman, R.J., VanRollins, M. & Harder, D.R. 1992. Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol 263, H519-H525.
    • (1992) Am J Physiol , vol.263
    • Gebremedhin, D.1    Ma, Y.-H.2    Falck, J.R.3    Roman, R.J.4    VanRollins, M.5    Harder, D.R.6
  • 16
    • 0021182202 scopus 로고
    • Pressure-dependent membrane depolarization in cat middle cerebral artery
    • Harder, D.R. 1984. Pressure-dependent membrane depolarization in cat middle cerebral artery. Circ Res 55, 197-202.
    • (1984) Circ Res , vol.55 , pp. 197-202
    • Harder, D.R.1
  • 17
    • 0031963859 scopus 로고    scopus 로고
    • Functional hyperemia in the brain: Hypothesis for astrocyte derived vasodilator metabolites
    • Harder, D.R., Alkayed, N.J., Lange, A.R., Gebremedhin, D. & Roman, R.J. 1998a. Functional hyperemia in the brain: Hypothesis for astrocyte derived vasodilator metabolites. Stroke 28, 229-234.
    • (1998) Stroke , vol.28 , pp. 229-234
    • Harder, D.R.1    Alkayed, N.J.2    Lange, A.R.3    Gebremedhin, D.4    Roman, R.J.5
  • 18
    • 0028904786 scopus 로고
    • Role of cytochrome P450 enzymes and metabolites of arachidonic acid in the control of vascular tone
    • Harder, D.R., Campbell, W.B. & Roman, R.J. 1995a. Role of cytochrome P450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J Vasc Res 32, 79-92.
    • (1995) J Vasc Res , vol.32 , pp. 79-92
    • Harder, D.R.1    Campbell, W.B.2    Roman, R.J.3
  • 19
    • 0028155755 scopus 로고
    • Formation and action of a P450 metabolite of arachidonic acid in cat cerebral microvessels
    • Harder, D.R., Gebremedhin, D., Narayanan, J. et al. 1994. Formation and action of a P450 metabolite of arachidonic acid in cat cerebral microvessels. Am J Physiol 266, H2098-2107.
    • (1994) Am J Physiol , vol.266
    • Harder, D.R.1    Gebremedhin, D.2    Narayanan, J.3
  • 20
    • 0031002404 scopus 로고    scopus 로고
    • Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecule in vascular tissue
    • Harder, D.R., Lange, A.R., Gebremedhin, D., Birks, E.K. & Roman, R.J. 1997. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecule in vascular tissue. J Vasc Res 34, 237-243.
    • (1997) J Vasc Res , vol.34 , pp. 237-243
    • Harder, D.R.1    Lange, A.R.2    Gebremedhin, D.3    Birks, E.K.4    Roman, R.J.5
  • 21
    • 0029947046 scopus 로고    scopus 로고
    • Identification of a putative microvascular oxygen sensor
    • Harder, D.R., Narayanan, J., Birks, E.K. et al. 1996. Identification of a putative microvascular oxygen sensor. Circ Res 79, 54-61.
    • (1996) Circ Res , vol.79 , pp. 54-61
    • Harder, D.R.1    Narayanan, J.2    Birks, E.K.3
  • 22
    • 0028952938 scopus 로고
    • Transduction of physical force by the vascular wall: Role of phospholipase and cytochrome P450 metabolites of arachidonic acid
    • Harder, D.R., Narayanan, J., Gebremedhin, D. & Roman, R.J. 1995b. Transduction of physical force by the vascular wall: Role of phospholipase and cytochrome P450 metabolites of arachidonic acid. TCM 5, 7-14.
    • (1995) TCM , vol.5 , pp. 7-14
    • Harder, D.R.1    Narayanan, J.2    Gebremedhin, D.3    Roman, R.J.4
  • 23
    • 0032425022 scopus 로고    scopus 로고
    • A common pathway for regulation of nutritive blood flow to the brain: Arterial muscle membrane potential and cytochrome P450 metabolites
    • Harder, D.R., Roman, R.J., Gebremedhin, D. & Lange, A.R. 1998b. A common pathway for regulation of nutritive blood flow to the brain: arterial muscle membrane potential and cytochrome P450 metabolites. Acta Physiol Scand 164, 527-532.
    • (1998) Acta Physiol Scand , vol.164 , pp. 527-532
    • Harder, D.R.1    Roman, R.J.2    Gebremedhin, D.3    Lange, A.R.4
  • 24
    • 0025064738 scopus 로고
    • Evidence for protein kinase C involvement in arteriolar myogenic reactivity
    • Hill, M.A., Falcone, J.C. & Meininger, G.A. 1990. Evidence for protein kinase C involvement in arteriolar myogenic reactivity. Am J Physiol 259, H1586-H1594.
    • (1990) Am J Physiol , vol.259
    • Hill, M.A.1    Falcone, J.C.2    Meininger, G.A.3
  • 25
    • 4243455978 scopus 로고
    • Myogenic response and wall mechanics of arterioles
    • Jackson, P.A. & Dulling, B.P. 1964. Myogenic response and wall mechanics of arterioles. Am J Physiol 257, H1147-1155.
    • (1964) Am J Physiol , vol.257
    • Jackson, P.A.1    Dulling, B.P.2
  • 26
    • 0000300408 scopus 로고
    • The myogenic response
    • D.F. Bohr, A.P. Somlyo, H.V. Sparks (eds). American Physiological Society, Bethesda
    • Johnson, P.C. 1980. The Myogenic Response. In: D.F. Bohr, A.P. Somlyo, H.V. Sparks (eds) Handbook of Physiology, Sect. 2. The Cardiovascular System, Vol. II, pp. 409-442. American Physiological Society, Bethesda.
    • (1980) Handbook of Physiology, Sect. 2. The Cardiovascular System , vol.2 , pp. 409-442
    • Johnson, P.C.1
  • 28
    • 0025967421 scopus 로고
    • Inhibitors of cytochrome P450 attenuate the myogenic response of dog renal arcuate arteries
    • Kauser, K., Clark, J.E., Masters, B.S. et al. 1991. Inhibitors of cytochrome P450 attenuate the myogenic response of dog renal arcuate arteries. Circ Res 68, 1154-1163.
    • (1991) Circ Res , vol.68 , pp. 1154-1163
    • Kauser, K.1    Clark, J.E.2    Masters, B.S.3
  • 31
    • 0033036730 scopus 로고    scopus 로고
    • Cytochrome P450 ω-hydroxylase senses oxygen in hamster muscle, but not cheek pouch epithelium, microcirculation
    • Lombard, J.L., Kunert, M.P., Roman, R.J., Falck, J.R., Harder, D.R. & Jackson, W.F. 1999. Cytochrome P450 ω-hydroxylase senses oxygen in hamster muscle, but not cheek pouch epithelium, microcirculation. Am J Physiol 276, H503-H508.
    • (1999) Am J Physiol , vol.276
    • Lombard, J.L.1    Kunert, M.P.2    Roman, R.J.3    Falck, J.R.4    Harder, D.R.5    Jackson, W.F.6
  • 32
    • 0002441454 scopus 로고    scopus 로고
    • Coupling of cerebral blood flow and metabolism
    • K.M.A. Welch, L.R. Caplan, D.J. Reis, B.K. Siejo & B. Weir (eds). Academic Press, London
    • Magestretti, P.J. 1997. Coupling of Cerebral Blood Flow and Metabolism. In: K.M.A. Welch, L.R. Caplan, D.J. Reis, B.K. Siejo & B. Weir (eds) Primer on Cerebrovascular Diseases, pp. 70-75. Academic Press, London.
    • (1997) Primer on Cerebrovascular Diseases , pp. 70-75
    • Magestretti, P.J.1
  • 33
    • 0025780578 scopus 로고
    • Cytochrome P450 metabolites of arachidonic acid
    • McGiff, J.C. 1991. Cytochrome P450 metabolites of arachidonic acid. Ann Rev Pharmacol Toxicol 31, 339-369.
    • (1991) Ann Rev Pharmacol Toxicol , vol.31 , pp. 339-369
    • McGiff, J.C.1
  • 34
    • 0034109792 scopus 로고    scopus 로고
    • Cerebral microvascular endothelial cell tube formation: Effect of blockade of astrocytic epoxyeicosatrienoic acid production
    • in press
    • Munzenmaier, D.H. & Harder, D.R. 2000. Cerebral microvascular endothelial cell tube formation: effect of blockade of astrocytic epoxyeicosatrienoic acid production. Am J Physiol in press.
    • (2000) Am J Physiol
    • Munzenmaier, D.H.1    Harder, D.R.2
  • 36
    • 0027177730 scopus 로고
    • Myogenic tone is coupled to phospholipase C and G protein activation in small cerebral arteries
    • Osol, G., Laher, I. & Kelly, M. 1993. Myogenic tone is coupled to phospholipase C and G protein activation in small cerebral arteries. Am J Physiol 265, H415-H420.
    • (1993) Am J Physiol , vol.265
    • Osol, G.1    Laher, I.2    Kelly, M.3
  • 37
    • 0028296987 scopus 로고
    • Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow
    • Zou, A.P., Imig, J.D., Kaldunski, M., Ortiz de Montellano, P.R., Sui, Z. & Roman, R.J. 1994. Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. Am J Physiol 266, 275-284.
    • (1994) Am J Physiol , vol.266 , pp. 275-284
    • Zou, A.P.1    Imig, J.D.2    Kaldunski, M.3    Ortiz De Montellano, P.R.4    Sui, Z.5    Roman, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.