Which endothelium-derived factors are really important in humans?

Biological Chemistry

Volumn 387, Issue 2, 2006, Pages 151-157

  Taddei, Stefano ^a   Virdis, Agostino ^a   Ghiadoni, Lorenzo ^a   Versari, Daniele ^a   Salvetti, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Circulation; Endothelium; Nitric oxide; Oxidative stress; Vascular reactivity

Indexed keywords

CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN 1; NITRIC OXIDE; PROSTANOID;

ATHEROSCLEROSIS; BLOOD VESSEL REACTIVITY; BLOOD VESSEL WALL; CARDIOVASCULAR RISK; CONFERENCE PAPER; CORONARY ARTERY DISEASE; DISEASE COURSE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; THROMBOSIS; VASODILATATION;

BIOLOGICAL FACTORS; ENDOTHELIUM, VASCULAR; HUMANS; VASODILATION;

EID: 32344436469     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2006.020     Document Type: Conference Paper

References (44)

1. Anderson, T.J., Uehata, A., Gerhard, M.D., Meredith, I.T., Knab, S., Delagrange, D., Lieberman, E.H., Ganz, P., Creager, M.A., and Yeung, A.C. (1995). Close relation of endothelial function in the human coronary and peripheral circulations. J. Am. Coll. Cardiol. 26, 1235-1241.
2. Brevetti, G., Silvestro, A., Schiano, V., and Chiariello, M. (2003). Endothelial dysfunction and cardiovascular risk prediction in peripheral arterial disease: additive value of flow-mediated dilation to ankle-brachial pressure index. Circulation 108, 2093-2098.
3. Celermajer, D.S., Sorensen, K.E., Gooch, V.M., Spiegelhalter, D.J., Miller, O.I., Sullivan, I.D., Lloyd, J.K., and Deanfield, J.E. (1992). Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 340, 1111-1115.
4. Cohen, R.A. and Vanhoutte, P.M. (1995). Endothelium-dependent hyperpolarization - beyond nitric oxide and cyclic GMP. Circulation 92, 3337-3349.
5. Davis, S.F., Yeung, A.C., Meredith, I.T., Charbonneau, F., Ganz, P., Selwyn, A.P., and Anderson, T.J. (1996). Early endothelial dysfunction predicts the development of transplant coronary artery disease at 1 year posttransplant. Circulation 93, 457-462.
6. Deanfield, J., Donald, A., Ferri, C., Halcox, J., Halligan, S., Lerman, A., Oliver, J.J., Pessina, A.C., Rizzoni, D., Rossi, G.P., et al. (2005). Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds. A statement by the Working Group on Endothelin and Endothelial Factors of the ESH. J. Hypertens. 23, 7-17.
7. Drexler, H. (1997). Endothelial dysfunction: clinical implications. Prog. Cardiovasc. Dis. 39, 287-324.
8. Fichtlscherer, S., Rosenberger, G., Walter, D.H., Breuer, S., Dimmeler, S., and Zeiher, A.M. (2000). Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease. Circulation 102, 1000-1006.
9. Furchgott, R.F. and Zawadzky, J.V. (1980). The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288, 373-376.
10. Ghiadoni, L., Taddei, S., Virdis, A., Sudano, I., Di Legge, V., Meola, M., Di Venanzio, L., and Salvetti, A. (1998). Endothelial function and common carotid artery wall thickening in patients with essential hypertension. Hypertension 32, 25-32.
11. Ghiadoni, L., Donald, A.E., Cropley, M., Mullen, M.J., Oakley, G., Taylor, M., O'Connor, G., Betteridge, J., Klein, N., Steptoe, A., and Deanfield, J.E. (2000). Mental stress induces transient endothelial dysfunction in humans. Circulation 102, 2473-2478.
12. Gokce, N., Keaney, J.F. Jr., Hunter, L.M., Watkins, M.T., Menzoian, J.O., and Vita, J.A. (2002). Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 105, 1567-1572.
13. Haynes, W.G. and Webb, D.J. (1998). Endothelin as a regulator of cardiovascular function in health and disease. J. Hypertens. 16, 1081-1098.
14. Halcox, J.P., Schenke, W.H., Zalos, G., Mincemoyer, R., Prasad, A., Waclawiw, M.A., Nour, K.R., and Quyyumi, A.A. (2002). Prognostic value of coronary vascular endothelial dysfunction. Circulation 106, 653-658.
15. Heitzer, T., Schlinzig, T., Krohn, K., Meinertz, T., and Munzel, T. (2001). Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 104, 2673-2678.
16. Hollemberg, S.M., Klein, L.W., Parrillo, J.E., Scherer, M., Burns, D., Tamburro, P., Oberoi, M., Johnson, M.R., and Costanzo, M.R. (2001). Coronary endothelial dysfunction after heart transplantation predicts allograft vasculopathy and cardiac death. Circulation 104, 3091-3096.
17. John, S. and Schmieder, R.E. (2000). Impaired endothelial function in arterial hypertension and hypercholesterolemia: potential mechanisms and differences. J. Hypertens. 18, 363-374.
18. Ludmer, P.L., Selwyn, A.P., Shook, T.L., Wayne, R.R., Mudge, G.H., Alexander, R.W., and Ganz, P. (1986). Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N. Engl. J. Med. 315, 1046-1051.
19. Lüscher, T.F. and Noll, G. (1996). Endothelial function as an endpoint in intervention trials: concepts, methods and current data. J. Hypertens. 14 (Suppl. 2), S111-S121.
20. Lüscher, T.F. and Vanhoutte, P.M. (1990). The Endothelium: Modulator of Cardiovascular Function (Boca Raton, USA: CRC Press).
21. Mulvany, M.J., Hansen, O.K., and Aalkjaer, C. (1978). Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers. Circ. Res. 43, 854-864.
22. Neunteufl, T., Heher, S., Katzenschlager, R., Wolfl, G., Kostner, K., Maurer, G., and Weidinger, F. (2000). Late prognostic value of flow-mediated dilation in the brachial artery of patients with chest pain. Am. J. Cardiol. 86, 207-210.
23. Panza, J.A., Quyyumi, A.A., Brush, J.E. Jr., and Epstein, S.E. (1990). Abnormal endothelium dependent vascular relaxation in patients with essential hypertension. N. Engl. J. Med. 323, 22-27.
24. Panza, J.A., Casino, P.R., Kilcoyne, C.M., and Quyyumi, A.A. (1993). Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation 87, 1468-1474.
25. Quyyumi, A.A., Dakak, N., Andrews, N.P., Husain, S., Arora, S., Gilligan, D.M., Panza, J.A., and Cannon, R.O. III (1995). Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis. J. Clin. Invest. 95, 1747-1755.
26. Ridker, P.M., Rifai, N., Rose, L., Buring, J.E., and Cook, N.R. (2002). Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N. Engl. J. Med. 347, 1557-1565.
27. Ross, R. (1999). Atherosclerosis - an inflammatory disease? N. Engl. J. Med. 340, 115-126.
28. -786C and glu298asp polymorphisms of the endothelial nitric oxide gene affect the forearm blood flow responses of Caucasian hypertensive patients. J. Am. Coll. Cardiol. 41, 938-948.
29. -786C endothelial nitric oxide synthase genotype is a novel risk factor for coronary artery disease in Caucasian patients of the GENICA study. J. Am. Coll. Cardiol. 41, 930-937.
30. Schachinger, V., Britten, M.B., and Zeiher, A.M. (2000). Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 101, 1899-1906.
31. Solzbach, U., Hornig, B., Jeserich, M., and Just, H. (1997). Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation 96, 1513-1519.
32. Sorensen, K.E., Celermajer, D.S., Spiegelhalter, D.J., Georgakopoulos, D., Robinson, J., Thomas, O., and Deanfield, J.E. (1995). Non-invasive measure of human endothelium-dependent arterial responses: accuracy and reproducibility. Br. Heart J. 74, 150-154.
33. Stern, M.D. (1975). In vivo evaluation of microcirculation by coherent light scattering. Nature 254, 56-58.
34. Suwaidi, J.A., Hamasaki, S., Higano, S.T., Nishimura, R.A., Holmes, D.R. Jr., and Lerman, A. (2000). Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 101, 948-954.
35. Taddei, S. and Salvetti, A. (2002). Endothelial dysfunction in essential hypertension: clinical implications. J. Hypertens. 20, 1671-1674.
36. Taddei, S., Virdis, A., Mattei, P., Natali, A., Ferrannini, E., and Salvetti, A. (1995). Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension. Circulation 92, 2911-2918.
37. Taddei, S., Virdis, A., Ghiadoni, L., Magagna, A., and Salvetti, A. (1997). Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension. Hypertension 29, 274-279.
38. Taddei, S., Virdis, A., Ghiadoni, L., Magagna, A., and Salvetti, A. (1998). Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation 97, 2222-2229.
39. Taddei, S., Ghiadoni, L., Virdis, A., Buralli, A., and Salvetti, A. (1999). Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired NO availability in essential hypertensive patients. Circulation 100, 1400-1405.
40. Taddei, S., Virdis, A., Ghiadoni, L., Magagna, A., Favilla, S., Pompella, A., and Salvetti, A. (2001). Restoration of nitric oxide availability after calcium antagonist treatment in essential hypertension. Hypertension 37, 943-948.
41. Taddei, S., Virdis, A., Ghiadoni, L., Sudano, I., and Salvetti, A. (2002). Effects of antihypertensive drugs on endothelial dysfunction: clinical implications. Drugs 62, 265-284.
42. Targonski, P.V., Bonetti, P.O., Pumper, G.M., Higano, S.T., Holmes, D.R. Jr., and Lerman, A. (2003). Coronary endothelial dysfunction is associated with an increased risk of cerebrovascular events. Circulation 107, 2805-2809.
43. Vallance, P., Coller, J., and Moncada, S. (1989). Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man. Lancet 2, 997-1000.
44. Zeiher, A.M., Schachlinger, V., Hohnloser, S.H., Saurbier, B., and Just, H. (1994). Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis. Circulation 89, 2525-2532.