메뉴 건너뛰기




Volumn 188, Issue 1, 2009, Pages 1-25

Cancer-causing karyotypes: chromosomal equilibria between destabilizing aneuploidy and stabilizing selection for oncogenic function

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ARTICLE; CELL TRANSFORMATION; CHROMOSOME; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; KARYOTYPE; MOLECULAR CLONING; MUTATION; ONCOGENE; PHENOTYPE; PRIORITY JOURNAL;

EID: 56849133855     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2008.08.016     Document Type: Article
Times cited : (50)

References (126)
  • 1
    • 0000800143 scopus 로고
    • Role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells
    • Levan A., and Biesele J.J. Role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells. Ann N Y Acad Sci 71 (1958) 1022-1053
    • (1958) Ann N Y Acad Sci , vol.71 , pp. 1022-1053
    • Levan, A.1    Biesele, J.J.2
  • 3
    • 0022572689 scopus 로고
    • Cytogenetic heterogeneity: its role in tumor evolution
    • Wolman S.R. Cytogenetic heterogeneity: its role in tumor evolution. Cancer Genet Cytogenet 19 (1986) 129-140
    • (1986) Cancer Genet Cytogenet , vol.19 , pp. 129-140
    • Wolman, S.R.1
  • 5
    • 10944262340 scopus 로고    scopus 로고
    • Mechanisms leading to chromosomal instability
    • Gollin S.M. Mechanisms leading to chromosomal instability. Semin Cancer Biol 15 (2005) 33-42
    • (2005) Semin Cancer Biol , vol.15 , pp. 33-42
    • Gollin, S.M.1
  • 6
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer C., Kinzler K.W., and Vogelstein B. Genetic instability in colorectal cancers. Nature 386 (1997) 623-627
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 7
    • 0032506125 scopus 로고    scopus 로고
    • Genetic instability of cancer cells is proportional to their degree of aneuploidy
    • Duesberg P., Rausch C., Rasnick D., and Hehlmann R. Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proc Natl Acad Sci U S A 95 (1998) 13692-13697
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13692-13697
    • Duesberg, P.1    Rausch, C.2    Rasnick, D.3    Hehlmann, R.4
  • 8
    • 0038668792 scopus 로고    scopus 로고
    • Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy
    • Fabarius A., Hehlmann R., and Duesberg P.H. Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy. Cancer Genet Cytogenet 143 (2003) 59-72
    • (2003) Cancer Genet Cytogenet , vol.143 , pp. 59-72
    • Fabarius, A.1    Hehlmann, R.2    Duesberg, P.H.3
  • 9
    • 1842611683 scopus 로고    scopus 로고
    • Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells
    • Duesberg P., Fabarius A., and Hehlmann R. Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells. IUBMB Life 56 (2004) 65-81
    • (2004) IUBMB Life , vol.56 , pp. 65-81
    • Duesberg, P.1    Fabarius, A.2    Hehlmann, R.3
  • 10
    • 27744565789 scopus 로고    scopus 로고
    • Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells
    • Li R., Hehlmann R., Sachs R., and Duesberg P. Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells. Cancer Genet Cytogenet 163 (2005) 44-56
    • (2005) Cancer Genet Cytogenet , vol.163 , pp. 44-56
    • Li, R.1    Hehlmann, R.2    Sachs, R.3    Duesberg, P.4
  • 12
    • 0007976836 scopus 로고
    • Zytologische Untersuchungen über die Natur maligner Tumoren: II. Teerkarzinome bei Mäusen [Cytological studies on the nature of malignant tumors: II. Tar carcinomas in mice. In German]
    • Winge O. Zytologische Untersuchungen über die Natur maligner Tumoren: II. Teerkarzinome bei Mäusen [Cytological studies on the nature of malignant tumors: II. Tar carcinomas in mice. In German]. Z Zellforsch Mikrosk Anat 10 (1930) 683-735
    • (1930) Z Zellforsch Mikrosk Anat , vol.10 , pp. 683-735
    • Winge, O.1
  • 13
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell P.C. The clonal evolution of tumor cell populations. Science 194 (1976) 23-28
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 15
    • 38349035679 scopus 로고    scopus 로고
    • Specific clones of spontaneously evolving karyotypes generate individuality of cancers
    • Fabarius A., Li R., Yerganian G., Hehlmann R., and Duesberg P. Specific clones of spontaneously evolving karyotypes generate individuality of cancers. Cancer Genet Cytogenet 180 (2008) 89-99
    • (2008) Cancer Genet Cytogenet , vol.180 , pp. 89-99
    • Fabarius, A.1    Li, R.2    Yerganian, G.3    Hehlmann, R.4    Duesberg, P.5
  • 17
    • 0035953435 scopus 로고    scopus 로고
    • Long-term dynamics of chromosomal instability in cancer: a transition probability model
    • Gusev Y., Kagansky V., and Dooley W.C. Long-term dynamics of chromosomal instability in cancer: a transition probability model. Math Comput Model 33 (2001) 1253-1273
    • (2001) Math Comput Model , vol.33 , pp. 1253-1273
    • Gusev, Y.1    Kagansky, V.2    Dooley, W.C.3
  • 19
    • 0004273731 scopus 로고
    • Academic Press, London, New York, San Francisco Vol. 1
    • Foulds L. Neoplastic development (1969), Academic Press, London, New York, San Francisco Vol. 1
    • (1969) Neoplastic development
    • Foulds, L.1
  • 20
    • 0020987278 scopus 로고
    • Karyotypic progression in human tumors
    • Wolman S.R. Karyotypic progression in human tumors. Cancer Metastasis Rev 2 (1983) 257-293
    • (1983) Cancer Metastasis Rev , vol.2 , pp. 257-293
    • Wolman, S.R.1
  • 26
    • 56849124208 scopus 로고    scopus 로고
    • Mitelman F, Johansson B, Mertens F, editors. Mitelman database of chromosome aberrations in cancer [Internet]. Updated quarterly. Available at http://cgap.nci.nih.gov/Chromosomes/Mitelman. Accessed June 2008.
    • Mitelman F, Johansson B, Mertens F, editors. Mitelman database of chromosome aberrations in cancer [Internet]. Updated quarterly. Available at http://cgap.nci.nih.gov/Chromosomes/Mitelman. Accessed June 2008.
  • 28
    • 0034133818 scopus 로고    scopus 로고
    • Patterns of genomic imbalances in human solid tumors (Review)
    • Gebhart E., and Liehr T. Patterns of genomic imbalances in human solid tumors (Review). Int J Oncol 16 (2000) 383-399
    • (2000) Int J Oncol , vol.16 , pp. 383-399
    • Gebhart, E.1    Liehr, T.2
  • 29
    • 38949218379 scopus 로고    scopus 로고
    • Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data
    • Baudis M. Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data. BMC Cancer 7 (2007) 226
    • (2007) BMC Cancer , vol.7 , pp. 226
    • Baudis, M.1
  • 30
    • 0030999555 scopus 로고    scopus 로고
    • A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
    • Spec No:S417-S474
    • Mitelman F., Mertens F., and Johansson B. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet (1997) 15 Spec No:S417-S474
    • (1997) Nat Genet , pp. 15
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3
  • 33
    • 0032006294 scopus 로고    scopus 로고
    • Genetic alterations in prostate cancer cell lines detected by comparative genomic hybridization
    • Nupponen N.N., Hyytinen E.R., Kallioniemi A.H., and Visakorpi T. Genetic alterations in prostate cancer cell lines detected by comparative genomic hybridization. Cancer Genet Cytogenet 101 (1998) 53-57
    • (1998) Cancer Genet Cytogenet , vol.101 , pp. 53-57
    • Nupponen, N.N.1    Hyytinen, E.R.2    Kallioniemi, A.H.3    Visakorpi, T.4
  • 34
    • 0031794480 scopus 로고    scopus 로고
    • Patterns of chromosomal imbalances in advanced urinary bladder cancer detected by comparative genomic hybridization
    • Richter J., Beffa L., Wagner U., Schraml P., Gasser T.C., Moch H., Mihatsch M.J., and Sauter G. Patterns of chromosomal imbalances in advanced urinary bladder cancer detected by comparative genomic hybridization. Am J Pathol 153 (1998) 1615-1621
    • (1998) Am J Pathol , vol.153 , pp. 1615-1621
    • Richter, J.1    Beffa, L.2    Wagner, U.3    Schraml, P.4    Gasser, T.C.5    Moch, H.6    Mihatsch, M.J.7    Sauter, G.8
  • 35
    • 0031847422 scopus 로고    scopus 로고
    • Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization
    • Weber R.G., Scheer M., Born I.A., Joos S., Cobbers J.M., Hofele C., Reifenberger G., Zöller J.E., and Lichter P. Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization. Am J Pathol 153 (1998) 295-303
    • (1998) Am J Pathol , vol.153 , pp. 295-303
    • Weber, R.G.1    Scheer, M.2    Born, I.A.3    Joos, S.4    Cobbers, J.M.5    Hofele, C.6    Reifenberger, G.7    Zöller, J.E.8    Lichter, P.9
  • 37
    • 3242750538 scopus 로고    scopus 로고
    • Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findings
    • Al-Mefty O., Kadri P.A., Pravdenkova S., Sawyer J.R., Stangeby C., and Husain M. Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findings. J Neurosurg 101 (2004) 210-218
    • (2004) J Neurosurg , vol.101 , pp. 210-218
    • Al-Mefty, O.1    Kadri, P.A.2    Pravdenkova, S.3    Sawyer, J.R.4    Stangeby, C.5    Husain, M.6
  • 40
    • 84932232901 scopus 로고
    • Relationships of viruses, chromosomes and carcinogenesis
    • Nichols W.W. Relationships of viruses, chromosomes and carcinogenesis. Hereditas 50 (1963) 51-80
    • (1963) Hereditas , vol.50 , pp. 51-80
    • Nichols, W.W.1
  • 41
    • 0017686931 scopus 로고
    • Chromosome analysis of hepatocellular carcinoma 7777 and correlation with α-fetoprotein production
    • Wolman S.R., Cohen T.I., and Becker F.F. Chromosome analysis of hepatocellular carcinoma 7777 and correlation with α-fetoprotein production. Cancer Res 37 (1977) 2624-2627
    • (1977) Cancer Res , vol.37 , pp. 2624-2627
    • Wolman, S.R.1    Cohen, T.I.2    Becker, F.F.3
  • 42
    • 0014601421 scopus 로고
    • A study of the cytology and karyotype of the canine transmissible venereal tumour
    • Murray M., James Z.H., and Martin W.B. A study of the cytology and karyotype of the canine transmissible venereal tumour. Res Vet Sci 10 (1969) 565-568
    • (1969) Res Vet Sci , vol.10 , pp. 565-568
    • Murray, M.1    James, Z.H.2    Martin, W.B.3
  • 43
    • 26744464306 scopus 로고
    • Chromosome abnormalities and carcinogenesis
    • Lima-de-Faria A. (Ed), American Elsevier Publishing, New York
    • Levan A. Chromosome abnormalities and carcinogenesis. In: Lima-de-Faria A. (Ed). Handbook of molecular cytology (1969), American Elsevier Publishing, New York 716-731
    • (1969) Handbook of molecular cytology , pp. 716-731
    • Levan, A.1
  • 44
    • 31844442380 scopus 로고    scopus 로고
    • Allograft theory: transmission of devil facial-tumour disease
    • Pearse A.M., and Swift K. Allograft theory: transmission of devil facial-tumour disease. Nature 439 (2006) 549
    • (2006) Nature , vol.439 , pp. 549
    • Pearse, A.M.1    Swift, K.2
  • 46
    • 0036145806 scopus 로고    scopus 로고
    • Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability
    • Roschke A.V., Stover K., Tonon G., Schäffer A.A., and Kirsch I.R. Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability. Neoplasia 4 (2002) 19-31
    • (2002) Neoplasia , vol.4 , pp. 19-31
    • Roschke, A.V.1    Stover, K.2    Tonon, G.3    Schäffer, A.A.4    Kirsch, I.R.5
  • 48
    • 2642574942 scopus 로고    scopus 로고
    • Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1
    • Grigorova M., Staines J.M., Ozdag H., Caldas C., and Edwards P.A. Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1. Cytogenet Genome Res 104 (2004) 333-340
    • (2004) Cytogenet Genome Res , vol.104 , pp. 333-340
    • Grigorova, M.1    Staines, J.M.2    Ozdag, H.3    Caldas, C.4    Edwards, P.A.5
  • 49
    • 18144409415 scopus 로고    scopus 로고
    • Comprehensive measurement of chromosomal instability in cancer cells: combination of fluorescence in situ hybridization and cytokinesis-block micronucleus assay
    • Camps J., Ponsa I., Ribas M., Prat E., Egozcue J., Peinado M.A., and Miro R. Comprehensive measurement of chromosomal instability in cancer cells: combination of fluorescence in situ hybridization and cytokinesis-block micronucleus assay. FASEB J 19 (2005) 828-830
    • (2005) FASEB J , vol.19 , pp. 828-830
    • Camps, J.1    Ponsa, I.2    Ribas, M.3    Prat, E.4    Egozcue, J.5    Peinado, M.A.6    Miro, R.7
  • 50
    • 19844366700 scopus 로고    scopus 로고
    • Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer
    • Gorringe K.L., Chin S.F., Pharoah P., Staines J.M., Oliveira C., Edwards P.A., and Caldas C. Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer. Carcinogenesis 26 (2005) 923-930
    • (2005) Carcinogenesis , vol.26 , pp. 923-930
    • Gorringe, K.L.1    Chin, S.F.2    Pharoah, P.3    Staines, J.M.4    Oliveira, C.5    Edwards, P.A.6    Caldas, C.7
  • 52
    • 0015156702 scopus 로고
    • DNA constancy in heteroploidy and the stem line theory of tumors
    • Kraemer P.M., Petersen D.F., and Van Dilla M.A. DNA constancy in heteroploidy and the stem line theory of tumors. Science 174 (1971) 714-717
    • (1971) Science , vol.174 , pp. 714-717
    • Kraemer, P.M.1    Petersen, D.F.2    Van Dilla, M.A.3
  • 56
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37 (1965) 614-636
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 58
    • 0033815915 scopus 로고    scopus 로고
    • Aneuploidy, the somatic mutation that makes cancer a species of its own
    • Duesberg P., and Rasnick D. Aneuploidy, the somatic mutation that makes cancer a species of its own. Cell Motil Cytoskeleton 47 (2000) 81-107
    • (2000) Cell Motil Cytoskeleton , vol.47 , pp. 81-107
    • Duesberg, P.1    Rasnick, D.2
  • 59
    • 0039488192 scopus 로고
    • Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells
    • Saxon P.J., Srivatsan E.S., and Stanbridge E.J. Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells. EMBO J 5 (1986) 3461-3466
    • (1986) EMBO J , vol.5 , pp. 3461-3466
    • Saxon, P.J.1    Srivatsan, E.S.2    Stanbridge, E.J.3
  • 60
    • 0028853405 scopus 로고
    • Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes
    • Theile M., Hartmann S., Scherthan H., Arnold W., Deppert W., Frege R., Glaab F., Haensch W., and Scherneck S. Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes. Oncogene 10 (1995) 439-447
    • (1995) Oncogene , vol.10 , pp. 439-447
    • Theile, M.1    Hartmann, S.2    Scherthan, H.3    Arnold, W.4    Deppert, W.5    Frege, R.6    Glaab, F.7    Haensch, W.8    Scherneck, S.9
  • 61
    • 13444309228 scopus 로고    scopus 로고
    • A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8
    • Seitz S., Frege R., Jacobsen A., Weimer J., Arnold W., von Haefen C., Niederacher D., Schmutzler R., Arnold N., and Scherneck S. A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8. Oncogene 24 (2005) 869-879
    • (2005) Oncogene , vol.24 , pp. 869-879
    • Seitz, S.1    Frege, R.2    Jacobsen, A.3    Weimer, J.4    Arnold, W.5    von Haefen, C.6    Niederacher, D.7    Schmutzler, R.8    Arnold, N.9    Scherneck, S.10
  • 62
    • 21144456793 scopus 로고    scopus 로고
    • Functional evidence of decreased tumorigenicity associated with monochromosome transfer of chromosome 14 in esophageal cancer and the mapping of tumor-suppressive regions to 14q32
    • Ko J.M., Yau W.L., Chan P.L., Lung H.L., Yang L., Lo P.H., Tang J.C., Srivastava G., Stanbridge E.J., and Lung M.L. Functional evidence of decreased tumorigenicity associated with monochromosome transfer of chromosome 14 in esophageal cancer and the mapping of tumor-suppressive regions to 14q32. Genes Chromosomes Cancer 43 (2005) 284-293
    • (2005) Genes Chromosomes Cancer , vol.43 , pp. 284-293
    • Ko, J.M.1    Yau, W.L.2    Chan, P.L.3    Lung, H.L.4    Yang, L.5    Lo, P.H.6    Tang, J.C.7    Srivastava, G.8    Stanbridge, E.J.9    Lung, M.L.10
  • 64
    • 0026053363 scopus 로고
    • Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells
    • Stewart N., and Bacchetti S. Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells. Virology 180 (1991) 49-57
    • (1991) Virology , vol.180 , pp. 49-57
    • Stewart, N.1    Bacchetti, S.2
  • 66
    • 27544453375 scopus 로고    scopus 로고
    • A network of genetic events sufficient to convert normal human cells to a tumorigenic state
    • Kendall S.D., Linardic C.M., Adam S.J., and Counter C.M. A network of genetic events sufficient to convert normal human cells to a tumorigenic state. Cancer Res 65 (2005) 9824-9828
    • (2005) Cancer Res , vol.65 , pp. 9824-9828
    • Kendall, S.D.1    Linardic, C.M.2    Adam, S.J.3    Counter, C.M.4
  • 67
    • 0029818753 scopus 로고    scopus 로고
    • Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen
    • Ewald D., Li M., Efrat S., Auer G., Wall R.J., Furth P.A., and Hennighausen L. Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science 273 (1996) 1384-1386
    • (1996) Science , vol.273 , pp. 1384-1386
    • Ewald, D.1    Li, M.2    Efrat, S.3    Auer, G.4    Wall, R.J.5    Furth, P.A.6    Hennighausen, L.7
  • 69
    • 0037992405 scopus 로고    scopus 로고
    • Are cancers dependent on oncogenes or on aneuploidy?
    • Duesberg P.H. Are cancers dependent on oncogenes or on aneuploidy?. Cancer Genet Cytogenet 143 (2003) 89-91
    • (2003) Cancer Genet Cytogenet , vol.143 , pp. 89-91
    • Duesberg, P.H.1
  • 70
    • 27944459717 scopus 로고    scopus 로고
    • SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
    • Ahuja D., Sáenz-Robles M.T., and Pipas J.M. SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 24 (2005) 7729-7745
    • (2005) Oncogene , vol.24 , pp. 7729-7745
    • Ahuja, D.1    Sáenz-Robles, M.T.2    Pipas, J.M.3
  • 71
    • 85047699318 scopus 로고
    • Chromosomal disturbances observed in human fetal renal cells transformed in vitro by simian virus 40 and carried in culture
    • Yerganian G., Shein H.M., and Enders J.F. Chromosomal disturbances observed in human fetal renal cells transformed in vitro by simian virus 40 and carried in culture. Cytogenetics 1 (1962) 314-324
    • (1962) Cytogenetics , vol.1 , pp. 314-324
    • Yerganian, G.1    Shein, H.M.2    Enders, J.F.3
  • 72
    • 0000095944 scopus 로고
    • The sequence of chromosome aberrations during SV 40 transformation of a human diploid cell strain
    • Moorhead P.S., and Saksela E. The sequence of chromosome aberrations during SV 40 transformation of a human diploid cell strain. Hereditas 52 (1965) 271-284
    • (1965) Hereditas , vol.52 , pp. 271-284
    • Moorhead, P.S.1    Saksela, E.2
  • 73
    • 0019312477 scopus 로고
    • Simian virus 40-induced chromosome changes in human epidermal cultures
    • Wolman S.R., Steinberg M.L., and Defendi V. Simian virus 40-induced chromosome changes in human epidermal cultures. Cancer Genet Cytogenet 2 (1980) 39-46
    • (1980) Cancer Genet Cytogenet , vol.2 , pp. 39-46
    • Wolman, S.R.1    Steinberg, M.L.2    Defendi, V.3
  • 74
    • 0025115324 scopus 로고
    • SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts
    • Ray F.A., Peabody D.S., Cooper J.L., Cram L.S., and Kraemer P.M. SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts. J Cell Biochem 42 (1990) 13-31
    • (1990) J Cell Biochem , vol.42 , pp. 13-31
    • Ray, F.A.1    Peabody, D.S.2    Cooper, J.L.3    Cram, L.S.4    Kraemer, P.M.5
  • 75
    • 0034724312 scopus 로고    scopus 로고
    • Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation, but is found to support aneuploidy
    • Li R., Sonik A., Stindl R., Rasnick D., and Duesberg P. Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation, but is found to support aneuploidy. Proc Natl Acad Sci U S A 97 (2000) 3236-3241
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3236-3241
    • Li, R.1    Sonik, A.2    Stindl, R.3    Rasnick, D.4    Duesberg, P.5
  • 77
    • 0000943342 scopus 로고
    • Agar suspension culture for the selective assay of cells transformed by polyoma virus
    • Macpherson I., and Montagnier L. Agar suspension culture for the selective assay of cells transformed by polyoma virus. Virology 23 (1964) 291-294
    • (1964) Virology , vol.23 , pp. 291-294
    • Macpherson, I.1    Montagnier, L.2
  • 78
    • 33750626189 scopus 로고    scopus 로고
    • Does aneuploidy cause cancer? [Erratum in: Curr Opin Cell Biol 2007;19:246]
    • Weaver B.A., and Cleveland D.W. Does aneuploidy cause cancer? [Erratum in: Curr Opin Cell Biol 2007;19:246]. Curr Opin Cell Biol 18 (2006) 658-667
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 658-667
    • Weaver, B.A.1    Cleveland, D.W.2
  • 81
    • 0030875221 scopus 로고    scopus 로고
    • Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization
    • Richter J., Jiang F., Görög J.P., Sartorius G., Egenter C., Gasser T.C., Moch H., Mihatsch M.J., and Sauter G. Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization. Cancer Res 57 (1997) 2860-2864
    • (1997) Cancer Res , vol.57 , pp. 2860-2864
    • Richter, J.1    Jiang, F.2    Görög, J.P.3    Sartorius, G.4    Egenter, C.5    Gasser, T.C.6    Moch, H.7    Mihatsch, M.J.8    Sauter, G.9
  • 84
    • 43049098968 scopus 로고    scopus 로고
    • Aneuploidy in upper gastro-intestinal tract cancers: a potential prognostic marker?
    • Doak S.H. Aneuploidy in upper gastro-intestinal tract cancers: a potential prognostic marker?. Mutat Res 651 (2008) 93-104
    • (2008) Mutat Res , vol.651 , pp. 93-104
    • Doak, S.H.1
  • 87
    • 11244320839 scopus 로고    scopus 로고
    • Wavelet transformations of tumor expression profiles reveals a pervasive genome-wide imprinting of aneuploidy on the cancer transcriptome
    • Aggarwal A., Leong S.H., Lee C., Kon O.L., and Tan P. Wavelet transformations of tumor expression profiles reveals a pervasive genome-wide imprinting of aneuploidy on the cancer transcriptome. Cancer Res 65 (2005) 186-194
    • (2005) Cancer Res , vol.65 , pp. 186-194
    • Aggarwal, A.1    Leong, S.H.2    Lee, C.3    Kon, O.L.4    Tan, P.5
  • 92
    • 34249734165 scopus 로고    scopus 로고
    • Chromosomal chaos and cancer
    • Duesberg P. Chromosomal chaos and cancer. Sci Am 296 5 (2007) 52-59
    • (2007) Sci Am , vol.296 , Issue.5 , pp. 52-59
    • Duesberg, P.1
  • 93
    • 0022630579 scopus 로고
    • Chemically induced aneuploidy in mammalian cells: mechanisms and biological significance in cancer
    • Oshimura M., and Barrett J.C. Chemically induced aneuploidy in mammalian cells: mechanisms and biological significance in cancer. Environ Mutagen 8 (1986) 129-159
    • (1986) Environ Mutagen , vol.8 , pp. 129-159
    • Oshimura, M.1    Barrett, J.C.2
  • 94
    • 11844262086 scopus 로고    scopus 로고
    • Does aneuploidy or mutation start cancer?
    • Duesberg P. Does aneuploidy or mutation start cancer?. Science 307 (2005) 41-42
    • (2005) Science , vol.307 , pp. 41-42
    • Duesberg, P.1
  • 95
    • 0020056341 scopus 로고
    • The effect of ploidy and colcemid on the frequency of spontaneous transformation of cultured cells
    • Saggioro D., Szpirer J., and Szpirer C. The effect of ploidy and colcemid on the frequency of spontaneous transformation of cultured cells. Cell Biol Int Rep 6 (1982) 29-38
    • (1982) Cell Biol Int Rep , vol.6 , pp. 29-38
    • Saggioro, D.1    Szpirer, J.2    Szpirer, C.3
  • 96
    • 9244263076 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Rajagopalan H., and Lengauer C. Aneuploidy and cancer. Nature 432 (2004) 338-341
    • (2004) Nature , vol.432 , pp. 338-341
    • Rajagopalan, H.1    Lengauer, C.2
  • 97
    • 0017346799 scopus 로고
    • Comparative cytogenetic and histologic studies on early malignant transformation in mesothelial tumors of the ovary
    • Knoerr-Gaertner H., Schuhmann R., Kraus H., and Uebele-Kallhardt B. Comparative cytogenetic and histologic studies on early malignant transformation in mesothelial tumors of the ovary. Hum Genet 35 (1977) 281-297
    • (1977) Hum Genet , vol.35 , pp. 281-297
    • Knoerr-Gaertner, H.1    Schuhmann, R.2    Kraus, H.3    Uebele-Kallhardt, B.4
  • 98
    • 0024366695 scopus 로고
    • Diagnostic and prognostic value of DNA cytometry in gynecologic cytology
    • Bocking A., and Chatelain R. Diagnostic and prognostic value of DNA cytometry in gynecologic cytology. Anal Quant Cytol Histol 11 (1989) 177-186
    • (1989) Anal Quant Cytol Histol , vol.11 , pp. 177-186
    • Bocking, A.1    Chatelain, R.2
  • 99
    • 0007938303 scopus 로고
    • Die Veränderungen der Häufigkeit euploider and aneuploider Chromosomenzahlen in der hepatektomierten Rattenleber bei Buttergelb-Verfütterung
    • [In German]
    • Marquardt H., and Glass E. Die Veränderungen der Häufigkeit euploider and aneuploider Chromosomenzahlen in der hepatektomierten Rattenleber bei Buttergelb-Verfütterung. Naturwissenschaften 44 (1957) 640 [In German]
    • (1957) Naturwissenschaften , vol.44 , pp. 640
    • Marquardt, H.1    Glass, E.2
  • 100
    • 0007938303 scopus 로고
    • Alterations of the frequencies of euploid and aneuploid chromosome numbers in the hepatectomized rat liver after feeding butter yellow
    • [In German]
    • Marquardt H., and Gläss E. Alterations of the frequencies of euploid and aneuploid chromosome numbers in the hepatectomized rat liver after feeding butter yellow. Naturwissenschaften 44 (1957) 640 [In German]
    • (1957) Naturwissenschaften , vol.44 , pp. 640
    • Marquardt, H.1    Gläss, E.2
  • 101
    • 85078507894 scopus 로고    scopus 로고
    • Multistep carcinogenesis: a chain reaction of aneuploidizations
    • Duesberg P., and Li R. Multistep carcinogenesis: a chain reaction of aneuploidizations. Cell Cycle 2 (2003) 202-210
    • (2003) Cell Cycle , vol.2 , pp. 202-210
    • Duesberg, P.1    Li, R.2
  • 105
    • 49849103726 scopus 로고    scopus 로고
    • Aneuploidy: cells losing their balance
    • Torres E.M., Williams B.R., and Amon A. Aneuploidy: cells losing their balance. Genetics 179 (2008) 737-746
    • (2008) Genetics , vol.179 , pp. 737-746
    • Torres, E.M.1    Williams, B.R.2    Amon, A.3
  • 106
    • 0033153475 scopus 로고    scopus 로고
    • Mouse autosomal trisomy: two's company, three's a crowd
    • Hernandez D., and Fisher E.M. Mouse autosomal trisomy: two's company, three's a crowd. Trends Genet 15 (1999) 241-247
    • (1999) Trends Genet , vol.15 , pp. 241-247
    • Hernandez, D.1    Fisher, E.M.2
  • 107
    • 0000049938 scopus 로고
    • Chromosome abnormalities in human reproductive wastage
    • Hassold T.J. Chromosome abnormalities in human reproductive wastage. Trends Genet 2 (1986) 105-110
    • (1986) Trends Genet , vol.2 , pp. 105-110
    • Hassold, T.J.1
  • 108
    • 84883833036 scopus 로고
    • Aneuploidy in the degenerative phase of serial cultivation of human cell strains
    • Saksela E., and Moorhead P.S. Aneuploidy in the degenerative phase of serial cultivation of human cell strains. Proc Natl Acad Sci U S A 50 (1963) 390-395
    • (1963) Proc Natl Acad Sci U S A , vol.50 , pp. 390-395
    • Saksela, E.1    Moorhead, P.S.2
  • 110
    • 0037178734 scopus 로고    scopus 로고
    • Debate surges over the origins of genomic defects in cancer
    • Marx J. Debate surges over the origins of genomic defects in cancer. Science 297 (2002) 544-546
    • (2002) Science , vol.297 , pp. 544-546
    • Marx, J.1
  • 111
    • 0037805151 scopus 로고    scopus 로고
    • Untangling the roots of cancer
    • Gibbs W.W. Untangling the roots of cancer. Sci Am 289 1 (2003) 56-65
    • (2003) Sci Am , vol.289 , Issue.1 , pp. 56-65
    • Gibbs, W.W.1
  • 112
    • 8844279091 scopus 로고    scopus 로고
    • Destructive cycles: the role of genomic instability and adaptation in carcinogenesis
    • Schneider B.L., and Kulesz-Martin M. Destructive cycles: the role of genomic instability and adaptation in carcinogenesis. Carcinogenesis 25 (2004) 2033-2044
    • (2004) Carcinogenesis , vol.25 , pp. 2033-2044
    • Schneider, B.L.1    Kulesz-Martin, M.2
  • 113
    • 24644520641 scopus 로고    scopus 로고
    • A long view of fashions in cancer research
    • Harris H. A long view of fashions in cancer research. Bioessays 27 (2005) 833-838
    • (2005) Bioessays , vol.27 , pp. 833-838
    • Harris, H.1
  • 114
    • 4644276792 scopus 로고    scopus 로고
    • Chromosomal rearrangement as the basis for human tumourigenesis
    • Radford I.R. Chromosomal rearrangement as the basis for human tumourigenesis. Int J Radiat Biol 80 (2004) 543-557
    • (2004) Int J Radiat Biol , vol.80 , pp. 543-557
    • Radford, I.R.1
  • 117
    • 56849101606 scopus 로고    scopus 로고
    • Lewin B, Cassimeris L, Lingappa VR, Plopper B. Cells. Chapter 13. Sudbury, MA: Jones & Bartlett, 2007.
    • Lewin B, Cassimeris L, Lingappa VR, Plopper B. Cells. Chapter 13. Sudbury, MA: Jones & Bartlett, 2007.
  • 119
    • 11844299802 scopus 로고    scopus 로고
    • From spindle checkpoint to cancer
    • Lengauer C., and Wang Z. From spindle checkpoint to cancer. Nat Genet 36 (2004) 1144-1145
    • (2004) Nat Genet , vol.36 , pp. 1144-1145
    • Lengauer, C.1    Wang, Z.2
  • 121
    • 0344823945 scopus 로고    scopus 로고
    • Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation
    • Akagi T., Sasai K., and Hanafusa H. Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation. Proc Natl Acad Sci U S A 100 (2003) 13567-13572
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13567-13572
    • Akagi, T.1    Sasai, K.2    Hanafusa, H.3
  • 122
    • 40449129966 scopus 로고    scopus 로고
    • Clonal selection in malignant transformation of human fibroblasts transduced with defined cellular oncogenes
    • Mahale A.M., Khan Z.A., Igarashi M., Nanjangud G.J., Qiao R.F., Yao S., Lee S.W., and Aaronson S.A. Clonal selection in malignant transformation of human fibroblasts transduced with defined cellular oncogenes. Cancer Res 68 (2008) 1417-1426
    • (2008) Cancer Res , vol.68 , pp. 1417-1426
    • Mahale, A.M.1    Khan, Z.A.2    Igarashi, M.3    Nanjangud, G.J.4    Qiao, R.F.5    Yao, S.6    Lee, S.W.7    Aaronson, S.A.8
  • 123
    • 10944219726 scopus 로고    scopus 로고
    • Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?
    • Teixeira M.R., and Heim S. Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?. Semin Cancer Biol 15 (2005) 3-12
    • (2005) Semin Cancer Biol , vol.15 , pp. 3-12
    • Teixeira, M.R.1    Heim, S.2
  • 124
    • 0034125650 scopus 로고    scopus 로고
    • Recurrent chromosome aberrations in cancer
    • Mitelman F. Recurrent chromosome aberrations in cancer. Mutat Res 462 (2000) 247-253
    • (2000) Mutat Res , vol.462 , pp. 247-253
    • Mitelman, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.