Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60)

Toxicology Letters

Volumn 183, Issue 1-3, 2008, Pages 105-111

  Wu, Ting Shuan ^a   Liao, Yi Chun ^a   Yu, Feng Yih ^a   Chang, Chia Hao ^a   Liu, Biing Hui ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Mitochondrial pathway; p53; Patulin; ROS; Sulfhydrl group

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DNA FRAGMENTATION FACTOR 45; MANNITOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; PATULIN; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TIRON; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CATALYSIS; CELL NUCLEUS; CELL STRAIN HEK293; CELL STRAIN HL 60; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; MITOCHONDRION; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA INTERFERENCE; WESTERN BLOTTING;

1,2-DIHYDROXYBENZENE-3,5-DISULFONIC ACID DISODIUM SALT; AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL SURVIVAL; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROMES C; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FREE RADICAL SCAVENGERS; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MANNITOL; MICROSCOPY, PHASE-CONTRAST; MOLECULAR STRUCTURE; MYCOTOXINS; PATULIN; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 56549106546     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.09.018     Document Type: Article

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