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Volumn 6, Issue 13, 2004, Pages 1133-1144

CD28 is required for T cell activation and IFN-gamma production by CD4 + and CD8 + T cells in response to Trypanosoma cruzi infection

Author keywords

Costimulation; Cytokines; Nitric oxide; Protozoan infection

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; NITRIC OXIDE;

EID: 5644302249     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2004.07.002     Document Type: Article
Times cited : (21)

References (55)
  • 1
    • 0035468745 scopus 로고    scopus 로고
    • Clinical and epidemiological aspects of Chagas disease
    • A. Prata Clinical and epidemiological aspects of Chagas disease Lancet Infect. Dis. 1 2001 92 100
    • (2001) Lancet Infect. Dis. , vol.1 , pp. 92-100
    • Prata, A.1
  • 2
    • 1142291085 scopus 로고    scopus 로고
    • Chagas disease: A role for autoimmunity
    • R.L. Tarleton Chagas disease: a role for autoimmunity Trends Parasitol. 10 2003 447 451
    • (2003) Trends Parasitol. , vol.10 , pp. 447-451
    • Tarleton, R.L.1
  • 3
    • 3142735123 scopus 로고    scopus 로고
    • The role of nitric oxide in the pathogenesis of Chagas disease
    • J.S. Silva, F.S. Machado, and G.A. Martins The role of nitric oxide in the pathogenesis of Chagas disease Front Biosci. 1 2003 314 325
    • (2003) Front Biosci. , vol.1 , pp. 314-325
    • Silva, J.S.1    MacHado, F.S.2    Martins, G.A.3
  • 4
    • 0028807425 scopus 로고
    • Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages
    • J.S. Silva, G.N.R. Vespa, M.A.C. Cardoso, J.C.S. Aliberti, and F.Q. Cunha Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages Infect. Immun. 63 1995 4862 4867
    • (1995) Infect. Immun. , vol.63 , pp. 4862-4867
    • Silva, J.S.1    Vespa, G.N.R.2    Cardoso, M.A.C.3    Aliberti, J.C.S.4    Cunha, F.Q.5
  • 5
    • 0030010929 scopus 로고    scopus 로고
    • IL-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes
    • J. Aliberti, M.A.G. Cardoso, G.A. Martins, and J.S. Silva IL-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes Infect. Immun. 64 1996 1961 1967
    • (1996) Infect. Immun. , vol.64 , pp. 1961-1967
    • Aliberti, J.1    Cardoso, M.A.G.2    Martins, G.A.3    Silva, J.S.4
  • 6
    • 0030025945 scopus 로고
    • Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: Role of NK cells
    • F. Cardillo, J.C. Voltarelli, S.G. Reed, and J.S. Silva Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells Infect. Immun. 64 1995 128 134
    • (1995) Infect. Immun. , vol.64 , pp. 128-134
    • Cardillo, F.1    Voltarelli, J.C.2    Reed, S.G.3    Silva, J.S.4
  • 7
    • 0028051548 scopus 로고
    • Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vivo
    • G.N.R. Vespa, F.Q. Cunha, and J.S. Silva Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vivo Infect. Immun. 62 1994 5177 5182
    • (1994) Infect. Immun. , vol.62 , pp. 5177-5182
    • Vespa, G.N.R.1    Cunha, F.Q.2    Silva, J.S.3
  • 9
    • 0032791044 scopus 로고    scopus 로고
    • Interferon-gamma modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: A possible role in immune response control
    • G.A. Martins, L.Q. Vieira, F.Q. Cunha, and J.S. Silva Interferon-gamma modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control Infect. Immun. 67 1999 3864 3871
    • (1999) Infect. Immun. , vol.67 , pp. 3864-3871
    • Martins, G.A.1    Vieira, L.Q.2    Cunha, F.Q.3    Silva, J.S.4
  • 10
    • 0031913243 scopus 로고    scopus 로고
    • Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase
    • C. Holscher, G. Kohler, U. Muller, H. Mossmann, G.A. Schaub, and F. Brombacher Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase Infect. Immun. 66 1998 1208 1215
    • (1998) Infect. Immun. , vol.66 , pp. 1208-1215
    • Holscher, C.1    Kohler, G.2    Muller, U.3    Mossmann, H.4    Schaub, G.A.5    Brombacher, F.6
  • 11
    • 0028330168 scopus 로고
    • Depletion of T-cell sub-populations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease
    • R.L. Tarleton, J. Sun, L. Zhang, and M. Postan Depletion of T-cell sub-populations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease Infect. Immun. 62 1994 1820 1829
    • (1994) Infect. Immun. , vol.62 , pp. 1820-1829
    • Tarleton, R.L.1    Sun, J.2    Zhang, L.3    Postan, M.4
  • 12
    • 0029991975 scopus 로고    scopus 로고
    • The influence of T cell subsets on Trypanosoma cruzi multiplication in different organs
    • M. Russo, N. Starobinas, M.C.G. Marcondes, P. Minoprio, and H.M. Joskowicz The influence of T cell subsets on Trypanosoma cruzi multiplication in different organs Immunol. Lett. 49 1996 163 168
    • (1996) Immunol. Lett. , vol.49 , pp. 163-168
    • Russo, M.1    Starobinas, N.2    Marcondes, M.C.G.3    Minoprio, P.4    Joskowicz, H.M.5
  • 13
    • 0035313039 scopus 로고    scopus 로고
    • Antigen-specific Th1 but not Th2 cells provide protection from lethal Trypanosoma cruzi infection in mice
    • S. Kumar, and R.L. Tarleton Antigen-specific Th1 but not Th2 cells provide protection from lethal Trypanosoma cruzi infection in mice J. Immunol. 166 2001 4596 4603
    • (2001) J. Immunol. , vol.166 , pp. 4596-4603
    • Kumar, S.1    Tarleton, R.L.2
  • 15
    • 0025741792 scopus 로고
    • Regulation of Trypanosoma cruzi infections in vivo and in vivo by transforming growth factor beta (TGF-beta)
    • J.S. Silva, D.R. Twardzik, and S.G. Reed Regulation of Trypanosoma cruzi infections in vivo and in vivo by transforming growth factor beta (TGF-beta) J. Exp. Med. 174 1991 539 545
    • (1991) J. Exp. Med. , vol.174 , pp. 539-545
    • Silva, J.S.1    Twardzik, D.R.2    Reed, S.G.3
  • 16
    • 0026537347 scopus 로고
    • CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T cell clones
    • F.A. Harding, J.G. McArthur, J.A. Gross, D.H. Raulet, and J.P. Allison CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T cell clones Nature 356 1992 607 609
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 17
    • 0025273486 scopus 로고
    • The murine homolog of the T lymphocyte antigen CD28: Molecular cloning and cell surface expression
    • J.A. Gross, T. St. John, and J.P. Allison The murine homolog of the T lymphocyte antigen CD28: molecular cloning and cell surface expression J. Immunol. 144 1990 3201 3210
    • (1990) J. Immunol. , vol.144 , pp. 3201-3210
    • Gross, J.A.1    St. John, T.2    Allison, J.P.3
  • 18
    • 0035059417 scopus 로고    scopus 로고
    • Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
    • B. Salomon, and J.A. Bluestone Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation Annu. Rev. Immunol. 19 2001 225 252
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 225-252
    • Salomon, B.1    Bluestone, J.A.2
  • 19
    • 0022632220 scopus 로고
    • A 44 kDa cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes
    • P.J. Martin, J.A. Ledbetter, Y. Morishita, C.H. June, P.G. Beatty, and J.A. Hansen A 44 kDa cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes J. Immunol. 136 1986 3282 3287
    • (1986) J. Immunol. , vol.136 , pp. 3282-3287
    • Martin, P.J.1    Ledbetter, J.A.2    Morishita, Y.3    June, C.H.4    Beatty, P.G.5    Hansen, J.A.6
  • 20
    • 0025947895 scopus 로고
    • CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells
    • M.K. Jenkins, P.S. Taylor, S.D. Norton, and K.B. Urdahl CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells J. Immunol. 147 1991 2461 2466
    • (1991) J. Immunol. , vol.147 , pp. 2461-2466
    • Jenkins, M.K.1    Taylor, P.S.2    Norton, S.D.3    Urdahl, K.B.4
  • 21
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
    • P.S. Linsley, W. Brady, L. Grosmaire, A. Aruffo, N.K. Damle, and J.A. Ledbetter Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation J. Exp. Med. 173 1991 721 730
    • (1991) J. Exp. Med. , vol.173 , pp. 721-730
    • Linsley, P.S.1    Brady, W.2    Grosmaire, L.3    Aruffo, A.4    Damle, N.K.5    Ledbetter, J.A.6
  • 25
    • 0031563160 scopus 로고    scopus 로고
    • + T cells in the absence of CD28/B7 costimulation
    • + T cells in the absence of CD28/B7 costimulation Cell. Immunol. 179 1997 74 83
    • (1997) Cell. Immunol. , vol.179 , pp. 74-83
    • Teh, H.S.1    Teh, S.J.2
  • 26
    • 0028316562 scopus 로고
    • Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen presenting cell types including resting B cells
    • M. Croft, L.M. Bradley, and S.L. Swan Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen presenting cell types including resting B cells J. Immunol. 152 1994 2675 2685
    • (1994) J. Immunol. , vol.152 , pp. 2675-2685
    • Croft, M.1    Bradley, L.M.2    Swan, S.L.3
  • 29
    • 0036467547 scopus 로고    scopus 로고
    • CD28 costimulation and parasite dose combine to influence the susceptibility of BALB/c mice to infection with Leishmania major
    • H.L. Compton, and J.P. Farrel CD28 costimulation and parasite dose combine to influence the susceptibility of BALB/c mice to infection with Leishmania major J. Immunol. 168 2002 1302 1308
    • (2002) J. Immunol. , vol.168 , pp. 1302-1308
    • Compton, H.L.1    Farrel, J.P.2
  • 30
    • 0029822863 scopus 로고    scopus 로고
    • CD28-deficient mice generate an impaired Th2 response to Schistosoma mansoni infection
    • C.L. King, J. Xianli, C.H. June, R. Abe, and K.P. Lee CD28-deficient mice generate an impaired Th2 response to Schistosoma mansoni infection Eur. J. Immunol. 10 1996 2448 2455
    • (1996) Eur. J. Immunol. , vol.10 , pp. 2448-2455
    • King, C.L.1    Xianli, J.2    June, C.H.3    Abe, R.4    Lee, K.P.5
  • 31
    • 0033568716 scopus 로고    scopus 로고
    • Role of CD28 in the generation of effector and memory responses required for resistance to Toxoplasma gondii
    • E.N. Villegas, M.M. Elloso, G. Reichman, R. Peach, and C.A. Hunter Role of CD28 in the generation of effector and memory responses required for resistance to Toxoplasma gondii J. Immunol. 163 1999 3344 3353
    • (1999) J. Immunol. , vol.163 , pp. 3344-3353
    • Villegas, E.N.1    Elloso, M.M.2    Reichman, G.3    Peach, R.4    Hunter, C.A.5
  • 32
    • 0344614706 scopus 로고    scopus 로고
    • Critical role of CD28 in protective immunity against Salmonella typhimurium
    • H.-W. Mittrücker, M. Kursar, A. Köhler, T.W. Mak, and S.H.E. Kaufmann Critical role of CD28 in protective immunity against Salmonella typhimurium J. Immunol. 163 1999 6769 6776
    • (1999) J. Immunol. , vol.163 , pp. 6769-6776
    • Mittrücker, H.-W.1    Kursar, M.2    Köhler, A.3    Mak, T.W.4    Kaufmann, S.H.E.5
  • 33
    • 0035889910 scopus 로고    scopus 로고
    • Role of CD28 for the generation and expansion of antigen-specific CD8+ T lymphocytes during infection with Listeria monocytogenes
    • H.-W. Mittrücker, M. Kursar, A. Köhler, R. Hurwitz, and S.H.E. Kaufmann Role of CD28 for the generation and expansion of antigen-specific CD8+ T lymphocytes during infection with Listeria monocytogenes J. Immunol. 167 2001 5620 5627
    • (2001) J. Immunol. , vol.167 , pp. 5620-5627
    • Mittrücker, H.-W.1    Kursar, M.2    Köhler, A.3    Hurwitz, R.4    Kaufmann, S.H.E.5
  • 38
    • 0034996188 scopus 로고    scopus 로고
    • CD28 costimulation is required not only to induce IL-12 receptor but also to render janus kinases/STAT4 responsive to IL-12 stimulation in TCR-triggered T cells
    • W.R. Park, C.S. Park, M. Tomura, H.J. Ahn, Y. Nakahira, M. Iwasaki, P. Gao, R. Abe, T. Hamaoka, and H. Fujiwara CD28 costimulation is required not only to induce IL-12 receptor but also to render janus kinases/STAT4 responsive to IL-12 stimulation in TCR-triggered T cells Eur. J. Immunol. 5 2001 1456 1464
    • (2001) Eur. J. Immunol. , vol.5 , pp. 1456-1464
    • Park, W.R.1    Park, C.S.2    Tomura, M.3    Ahn, H.J.4    Nakahira, Y.5    Iwasaki, M.6    Gao, P.7    Abe, R.8    Hamaoka, T.9    Fujiwara, H.10
  • 39
    • 0035108525 scopus 로고    scopus 로고
    • Differential requirement of CD28 for IL-12 receptor expression and function in CD4(+) and CD8(+) T cells
    • M.M. Elloso, and P. Scott Differential requirement of CD28 for IL-12 receptor expression and function in CD4(+) and CD8(+) T cells Eur. J. Immunol. 31 2001 384 395
    • (2001) Eur. J. Immunol. , vol.31 , pp. 384-395
    • Elloso, M.M.1    Scott, P.2
  • 40
    • 0018184199 scopus 로고
    • Tissue tropism of different Trypanosoma cruzi strains
    • R.C. Melo, and Z. Brener Tissue tropism of different Trypanosoma cruzi strains J. Parasitol. 64 1978 475 482
    • (1978) J. Parasitol. , vol.64 , pp. 475-482
    • Melo, R.C.1    Brener, Z.2
  • 41
    • 0033568303 scopus 로고    scopus 로고
    • The CD28/B7 interaction is not required for resistance to Toxoplasma gondii in the brain but contributes to the development of immunopathology
    • G. Reichmann, E.N. Villegas, L. Craig, R. Peach, and C.A. Hunter The CD28/B7 interaction is not required for resistance to Toxoplasma gondii in the brain but contributes to the development of immunopathology J. Immunol. 163 1999 3354 3362
    • (1999) J. Immunol. , vol.163 , pp. 3354-3362
    • Reichmann, G.1    Villegas, E.N.2    Craig, L.3    Peach, R.4    Hunter, C.A.5
  • 42
    • 0346366993 scopus 로고    scopus 로고
    • Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo
    • J.C. Wang, and A.M. Livingstone Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo J. Immunol. 171 2003 6339 6343
    • (2003) J. Immunol. , vol.171 , pp. 6339-6343
    • Wang, J.C.1    Livingstone, A.M.2
  • 43
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • D.J. Shedlock, and H. Shen Requirement for CD4 T cell help in generating functional CD8 T cell memory Science 300 2003 337 339
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 44
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • J.C. Sun, and M.J. Bevan Defective CD8 T cell memory following acute infection without CD4 T cell help Science 300 2003 339 342
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 45
    • 0032963292 scopus 로고    scopus 로고
    • CD28-deficient mice are highly resistant to collagen-induced arthritis
    • Y. Tada, K. Nagasawa, A. Ho, F. Morito, O. Ushiyama, and N. Suzuki CD28-deficient mice are highly resistant to collagen-induced arthritis J. Immunol. 162 1999 203 208
    • (1999) J. Immunol. , vol.162 , pp. 203-208
    • Tada, Y.1    Nagasawa, K.2    Ho, A.3    Morito, F.4    Ushiyama, O.5    Suzuki, N.6
  • 46
    • 0034642343 scopus 로고    scopus 로고
    • Trypanosoma cruzi-infected cardiomyocytes produce chemokines and cytokines that trigger potent nitric oxide-dependent tripanocidal activity
    • F.S. Machado, G.A. Martins, J.C. Aliberti, F.L.A.C. Mestriner, F.Q. Cunha, and J.S. Silva Trypanosoma cruzi-infected cardiomyocytes produce chemokines and cytokines that trigger potent nitric oxide-dependent tripanocidal activity Circulation 102 2000 3003 3008
    • (2000) Circulation , vol.102 , pp. 3003-3008
    • MacHado, F.S.1    Martins, G.A.2    Aliberti, J.C.3    Mestriner, F.L.A.C.4    Cunha, F.Q.5    Silva, J.S.6
  • 47
    • 0035149345 scopus 로고    scopus 로고
    • Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection
    • V. Michailowsky, N.M. Silva, C.D. Rocha, L.Q. Vieira, J. Lannes-Vieira, and R.T. Gazzinelli Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection Am. J. Pathol. 159 2001 1723 1733
    • (2001) Am. J. Pathol. , vol.159 , pp. 1723-1733
    • Michailowsky, V.1    Silva, N.M.2    Rocha, C.D.3    Vieira, L.Q.4    Lannes-Vieira, J.5    Gazzinelli, R.T.6
  • 48
    • 0028347462 scopus 로고
    • IFN and virus-inducible expression of an immediate early gene, crg-2/IP-10, and a delayed gene, I-A alpha in astrocytes and microglia
    • P. Vanguri, and J.M. Farber IFN and virus-inducible expression of an immediate early gene, crg-2/IP-10, and a delayed gene, I-A alpha in astrocytes and microglia J. Immunol. 152 1994 1411 1418
    • (1994) J. Immunol. , vol.152 , pp. 1411-1418
    • Vanguri, P.1    Farber, J.M.2
  • 49
    • 0033943272 scopus 로고    scopus 로고
    • Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: Tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi
    • A. Talvani, C.S. Ribeiro, J.C. Aliberti, V. Michailowsky, P.V. Santos, and S.M. Murta Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi Microbes Infect. 8 2000 851 866
    • (2000) Microbes Infect. , vol.8 , pp. 851-866
    • Talvani, A.1    Ribeiro, C.S.2    Aliberti, J.C.3    Michailowsky, V.4    Santos, P.V.5    Murta, S.M.6
  • 50
    • 0024506159 scopus 로고
    • Regulation of a lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
    • T. Lindsten, C.H. June, J.A. Ledbetter, G. Stella, and C.B. Thompson Regulation of a lymphokine messenger RNA stability by a surface-mediated T cell activation pathway Science 244 1989 339 343
    • (1989) Science , vol.244 , pp. 339-343
    • Lindsten, T.1    June, C.H.2    Ledbetter, J.A.3    Stella, G.4    Thompson, C.B.5
  • 51
    • 0028230410 scopus 로고
    • CD28-mediates costimulation is necessary for optimal proliferation of murine NK cells
    • D. Nandi, J.A. Gross, and J.P. Allison CD28-mediates costimulation is necessary for optimal proliferation of murine NK cells J. Immunol. 152 1994 3361 3369
    • (1994) J. Immunol. , vol.152 , pp. 3361-3369
    • Nandi, D.1    Gross, J.A.2    Allison, J.P.3
  • 52
    • 0035873434 scopus 로고    scopus 로고
    • Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways
    • Y. Hawakawa, K. Takeda, H. Yagita, L. Vankaer, I. Saiki, and K. Okumura Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways J. Immunol. 166 2001 6012 6018
    • (2001) J. Immunol. , vol.166 , pp. 6012-6018
    • Hawakawa, Y.1    Takeda, K.2    Yagita, H.3    Vankaer, L.4    Saiki, I.5    Okumura, K.6
  • 53
    • 0033563026 scopus 로고    scopus 로고
    • IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12-induced IFN-γ
    • W. Walker, M. Aste-Amezaga, R.A. Kastelein, G. Trinchieri, and C.A. Hunter IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12-induced IFN-γ J. Immunol. 162 1999 5894 5901
    • (1999) J. Immunol. , vol.162 , pp. 5894-5901
    • Walker, W.1    Aste-Amezaga, M.2    Kastelein, R.A.3    Trinchieri, G.4    Hunter, C.A.5
  • 54
    • 0031091746 scopus 로고    scopus 로고
    • The role of the CD28/B7 interaction in the regulation of NK cell response during infection with Toxoplasma gondii
    • C.A. Hunter, L. Ellis-Neyer, K.E. Gabriel, M.K. Kennedy, K.H. Grabsteins, and P.S. Linsley The role of the CD28/B7 interaction in the regulation of NK cell response during infection with Toxoplasma gondii J. Immunol. 158 1997 2285 2293
    • (1997) J. Immunol. , vol.158 , pp. 2285-2293
    • Hunter, C.A.1    Ellis-Neyer, L.2    Gabriel, K.E.3    Kennedy, M.K.4    Grabsteins, K.H.5    Linsley, P.S.6
  • 55
    • 0031965580 scopus 로고    scopus 로고
    • Interleukin-12-activated natural killer cells recognize B7 costimulatory molecules on tumor cells and autologous dendritic cells
    • A.B. Geldhof, M. Moser, L. Lespagnard, K. Thielemans, and P. De Baetselier Interleukin-12-activated natural killer cells recognize B7 costimulatory molecules on tumor cells and autologous dendritic cells Blood 91 1998 196 206
    • (1998) Blood , vol.91 , pp. 196-206
    • Geldhof, A.B.1    Moser, M.2    Lespagnard, L.3    Thielemans, K.4    De Baetselier, P.5


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