CD28 costimulation is required not only to induce IL-12 receptor but also to render Janus kinases/STAT4 responsive to IL-12 stimulation in TCR-triggered T cells

European Journal of Immunology

Volumn 31, Issue 5, 2001, Pages 1456-1464

  Park, Woong Ryeon ^a   Park, Cheung Seog ^a   Tomura, Michio ^a   Ahn, Hyun Jong ^a   Nakahira, Yasukiyo ^a   Iwasaki, Masayuki ^a   Gao, Ping ^a   Abe, Ryo ^b   Hamaoka, Toshiyuki ^a   Fujiwara, Hiromi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

CD28; Costimulation; IL 12; IL 12 receptor; Signal transduction

Indexed keywords

CD28 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12 RECEPTOR; JANUS KINASE; JANUS KINASE 2; MONOCLONAL ANTIBODY CD3; RECOMBINANT INTERLEUKIN 12; STAT4 PROTEIN; STAT6 PROTEIN; T LYMPHOCYTE RECEPTOR; TYK2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; INTERFERON PRODUCTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD28; BLOTTING, WESTERN; CELLS, CULTURED; DNA-BINDING PROTEINS; ENZYME ACTIVATION; FLOW CYTOMETRY; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-4; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT4 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TRANS-ACTIVATORS;

EID: 0034996188     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200105)31:5<1456::AID-IMMU1456>3.0.CO;2-A     Document Type: Article

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