Runt-related gene 2 in endothelial cells: Inducible expression and specific regulation of cell migration and invasion

Cancer Research

Volumn 61, Issue 13, 2001, Pages 4994-5001

  Sun, Lixin ^a   Passaniti, Antonino ^a   Vitolo, Michele ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR; UROKINASE;

ANGIOGENESIS; ARTICLE; BONE MARROW; CELL INVASION; CELL MIGRATION; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOMA; METASTASIS; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RUNT RELATED GENE 2; TUMOR GROWTH;

ANIMALS; BONE MARROW CELLS; CATTLE; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CORE BINDING FACTOR ALPHA SUBUNITS; DNA, COMPLEMENTARY; ENDOPEPTIDASES; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMANS; INSULIN-LIKE GROWTH FACTOR I; NEOPLASM PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0035393430     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Tumor angiogenesis: Past, present, and the near future
2. Angiogenesis and cancer: AACR special conference in cancer research
3. Angiogenesis and cancer metastasis
4. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia
5. Evidence of increased angiogenesis in patients with acute myeloid leukemia
6. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes
7. Increased bone marrow angiogenesis in B cell chronic lymphocytic leukemia
8. Protein tyrosine phosphatase regulation of endothelial cell apoptosis and differentiation
9. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
10. The hemostatic system as a regulator of angiogenesis
11. Regulation of capillary formation by laminin and other components of the extracellular matrix
12. Metalloproteases and urokinase in angiogenesis and tumor progression
13. Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: Implications for angiogenesis
14. Extracellular matrix remodeling and cellular differentiation
15. Overexpression of Ets-1 transcription factor in angiosareoma of the skin
16. The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor
17. Transcription factor ETS-1 as a molecular target for angiogenesis inhibition
18. Induction of Ets-1 in endothelial cells during reendothelialization after denuding injury
19. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of turnout xenografts
20. The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF
21. Morphogenesis of the first blood vessels
22. Vezfl: A Zn finger transcription factor restricted to endothelial cells and their precursors
23. Induction of vascular endothelial growth factor by tumor necrosis factor a in human glioma cells. Possible roles of SP-1
24. Pathogenesis of atherosclerosis
25. Estrogen stimulates delayed mitogen-activated protein kinase activity in human endothelial cells via an autocrine loop that involves basic fibroblast growth factor
26. Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis
27. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
28. Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia
29. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
30. A role for hematopoietic stem cells in promoting angiogenesis
31. Osf2/RUNX2: A transcriptional activator of osteoblast differentiation
32. Runt homology domain protein in osteoblast differentiation: AML3/CBFA 1 is a major component of a bone-specific complex
33. Positive and negative regulation of chondrogenesis by splice variants of PEBP2αA/CBFα1 in clonal mouse EC cells, ATDC5
34. Indispensable role of the transcription factor PEBP2/CBF in angiogenic activity of a murine endothelial cell MSS3 1
35. Basement membrane complexes with biological activity
36. Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell line
37. HMEC-1: Establishment of an immortalized human microvascular endothelial cell line
38. Identification of anti-invasive but noncytotoxic chemotherapeutic agents using the tetrazolium dye MTT to quantitate viable cells in Matrigel
39. Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: Its regional distribution and developmental expression in the rat brain
40. Role of the α2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor
41. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor
42. Evidence for circulating bone marrow-derived endothelial cells
43. Heterogeneity of endothelial cells. Specific markers
44. Heterogeneity of the endothelial cell and its role in organ preference of tumor metastasis
45. Increased expression of preprotachyidnin-I and neurokinin receptors in human breast cancer cells: Implications for bone marrow metastasis
46. In vitro differentiation of endothelial cells from AC133-positive progenitor cells
47. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma
48. Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
49. Role of insulin-like growth factors in embryonic and postnatal growth
50. MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, RUNX2
51. Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2
52. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the αvβ3 integrin, osteopontin, and thrombin
53. Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
54. Matrix metalloproteinases
55. Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF