Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss

Apoptosis

Volumn 13, Issue 12, 2008, Pages 1479-1493

  Gilbert, Stéphane ^a,b   Ruel, Alexandre ^b   Loranger, Anne ^b   Marceau, Normand ^a,b  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Bid; Caspases; Cytochrome c; DEDD; DISC; Fas receptor signaling pathways; FasL; Hepatocytes; Keratin 8 and 18

Indexed keywords

CASPASE 8; CYTOCHROME C; CYTOKERATIN 18; CYTOKERATIN 8; FAS LIGAND; PROCASPASE 3;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IMMUNOPRECIPITATION; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; UBIQUITINATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES; ANTIGENS, CD95; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASES; CELLS, CULTURED; CYTOCHROMES C; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; ENZYME ACTIVATION; HEPATOCYTES; INTERMEDIATE FILAMENTS; KERATIN-18; KERATIN-8; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION;

EID: 56349146105     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0274-x     Document Type: Article

References (54)

1. S Kumar 1999 Mechanisms mediating caspase activation in cell death Cell Death Differ 6 1060 1066 10.1038/sj.cdd.4400600
2. TS Zheng RA Flavell 1999 Apoptosis. All's well that ends dead Nature 400 410 411 10.1038/22659
3. ME Peter PH Krammer 2003 The CD95(APO-1/Fas) DISC and beyond Cell Death Differ 10 26 35 10.1038/sj.cdd.4401186
4. BC Barnhart EC Alappat ME Peter 2003 The CD95 type I/type II model Semin Immunol 15 185 193 10.1016/S1044-5323(03)00031-9
5. SM Park ME Peter 2008 microRNAs and death receptors Cytokine Growth Factor Rev 19 303 311 10.1016/j.cytogfr.2008.04.011
6. X Wang 2001 The expanding role of mitochondria in apoptosis Genes Dev 15 2922 2933
7. BC Barnhart JC Lee EC Alappat ME Peter 2003 The death effector domain protein family Oncogene 22 8634 8644 10.1038/sj.onc.1207103
8. S Fulda E Meyer KM Debatin 2000 Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression Cancer Res 60 3947 3956
9. D Dinsdale JC Lee G Dewson GM Cohen ME Peter 2004 Intermediate filaments control the intracellular distribution of caspases during apoptosis Am J Pathol 164 395 407
10. JC Lee O Schickling AH Stegh 2002 DEDD regulates degradation of intermediate filaments during apoptosis J Cell Biol 158 1051 1066 10.1083/jcb.200112124
11. B Schutte M Henfling FC Ramaekers 2006 DEDD association with cytokeratin filaments correlates with sensitivity to apoptosis Apoptosis 11 1561 1572 10.1007/s10495-006-9113-0
12. R Moll WW Franke DL Schiller 1982 The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells Cell 31 11 24 10.1016/0092-8674(82)90400-7
13. J Schweizer PE Bowden PA Coulombe 2006 New consensus nomenclature for mammalian keratins J Cell Biol 174 169 174 10.1083/jcb.200603161
14. PA Coulombe P Wong 2004 Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds Nat Cell Biol 6 699 706 10.1038/ncb0804-699
15. EB Lane BL Hogan M Kurkinen JI Garrels 1983 Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo Nature 303 701 704 10.1038/303701a0
16. H Lu M Hesse B Peters TM Magin 2005 Type II keratins precede type I keratins during early embryonic development Eur J Cell Biol 84 709 718 10.1016/j.ejcb.2005.04.001
17. NO Ku MB Omary 2000 Keratins turn over by ubiquitination in a phosphorylation-modulated fashion J Cell Biol 149 547 552 10.1083/jcb.149.3.547
18. RG Oshima H Baribault C Caulin 1996 Oncogenic regulation and function of keratins 8 and 18 Cancer Metastasis Rev 15 445 471 10.1007/BF00054012
19. NO Ku RM Soetikno MB Omary 2003 Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury Hepatology 37 1006 1014 10.1053/jhep.2003.50181
20. NO Ku P Strnad BH Zhong GZ Tao MB Omary 2007 Keratins let liver live: mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies Hepatology 46 1639 1649 10.1002/hep.21976
21. N Marceau A Loranger S Gilbert N Daigle S Champetier 2001 Keratin-mediated resistance to stress and apoptosis in simple epithelial cells in relation to health and disease Biochem Cell Biol 79 543 555 10.1139/bcb-79-5-543
22. N Marceau B Schutte S Gilbert 2007 Dual roles of intermediate filaments in apoptosis Exp Cell Res 313 2265 2281 10.1016/j.yexcr.2007.03.038
23. RG Oshima 2002 Apoptosis and keratin intermediate filaments Cell Death Differ 9 486 492 10.1038/sj.cdd.4400988
24. S Nagata 1999 Fas ligand-induced apoptosis Annu Rev Genet 33 29 55 10.1146/annurev.genet.33.1.29
25. V Lacronique A Mignon M Fabre 1996 Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice Nat Med 2 80 86 10.1038/nm0196-80
26. A de la Coste M Fabre N [tmp] McDonell 1999 Differential protective effects of Bcl-xL and Bcl-2 on apoptotic liver injury in transgenic mice Am J Physiol 277 G702 G708
27. XM Yin K Wang A Gross 1999 Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis Nature 400 886 891 10.1038/23730
28. S Gilbert A Loranger N Daigle N Marceau 2001 Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation J Cell Biol 154 763 773 10.1083/jcb.200102130
29. S Gilbert A Loranger N Marceau 2004 Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells Mol Cell Biol 24 7072 7081 10.1128/MCB.24.16.7072-7081. 2004
30. DC Huang M Hahne M Schroeter 1999 Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L) Proc Natl Acad Sci USA 96 14871 14876 10.1073/pnas.96.26.14871
31. H Baribault J Penner RV Iozzo M Wilson-Heiner 1994 Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice Genes Dev 8 2964 2973 10.1101/gad.8.24.2964
32. A Loranger S Duclos A Grenier 1997 Simple epithelium keratins are required for maintenance of hepatocyte integrity Am J Pathol 151 1673 1683
33. N Marceau S Gilbert A Loranger 2004 Uncovering the roles of intermediate filaments in apoptosis Methods Cell Biol 78 95 129 10.1016/S0091-679X(04)78005-X
34. Y Zhao WX Ding T Qian S Watkins JJ Lemasters XM Yin 2003 Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement Gastroenterology 125 854 867 10.1016/S0016-5085(03)01066-7
35. KK Nadakavukaren JJ Nadakavukaren LB Chen 1985 Increased rhodamine 123 uptake by carcinoma cells Cancer Res 45 6093 6099
36. UK Laemmli 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 680 685 10.1038/227680a0
37. C Scaffidi S Fulda A Srinivasan 1998 Two CD95 (APO-1/Fas) signaling pathways EMBO J 17 1675 1687 10.1093/emboj/17.6.1675
38. C Caulin GS Salvesen RG Oshima 1997 Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis J Cell Biol 138 1379 1394 10.1083/jcb.138.6.1379
39. R Ni Y Tomita K Matsuda 1994 Fas-mediated apoptosis in primary cultured mouse hepatocytes Exp Cell Res 215 332 337 10.1006/excr.1994.1349
40. M Gyrd-Hansen T Farkas N Fehrenbacher 2006 Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9 Mol Cell Biol 26 7880 7891 10.1128/MCB.00716-06
41. MA [tmp] McDonnell D Wang SM Khan MG Vander Heiden A Kelekar 2003 Caspase-9 is activated in a cytochrome c-independent manner early during TNFalpha-induced apoptosis in murine cells Cell Death Differ 10 1005 1015 10.1038/sj.cdd.4401271
42. AB Berger KB Sexton M Bogyo 2006 Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity Cell Res 16 961 963 10.1038/sj.cr.7310112
43. T Date S Mochizuki AJ Belanger 2003 Differential effects of membrane and soluble Fas ligand on cardiomyocytes: role in ischemia/reperfusion injury J Mol Cell Cardiol 35 811 821 10.1016/S0022-2828(03)00139-1
44. DN Zacks QD Zheng Y Han R Bakhru JW Miller 2004 FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment Invest Ophthalmol Vis Sci 45 4563 4569 10.1167/iovs.04-0598
45. JC Lee GX Wang O Schickling ME Peter 2005 Fusing DEDD with ubiquitin changes its intracellular localization and apoptotic potential Apoptosis 10 1483 1495 10.1007/s10495-005-1833-z
46. I Schmitz H Weyd A Krueger 2004 Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort J Immunol 172 2194 2200
47. G Brumatti M Yon FA Castro 2008 Conversion of CD95 (Fas) Type II into Type I signaling by sub-lethal doses of cycloheximide Exp Cell Res 314 554 563 10.1016/j.yexcr.2007.11.003
48. C Scaffidi I Schmitz J Zha SJ Korsmeyer PH Krammer ME Peter 1999 Differential modulation of apoptosis sensitivity in CD95 type I and type II cells J Biol Chem 274 22532 22538 10.1074/jbc.274.32.22532
49. L Galarneau A Loranger S Gilbert N Marceau 2007 Keratins modulate hepatic cell adhesion, size and G1/S transition Exp Cell Res 313 179 194 10.1016/j.yexcr.2006.10.007
50. J Mathew L Galarneau A Loranger S Gilbert N Marceau 2008 Keratin-protein kinase C interaction in reactive oxygen species-induced hepatic cell death through mitochondrial signaling Free Radic Biol Med 45 413 424 10.1016/j.freeradbiomed.2008.04.031
51. NW Werneburg ME Guicciardi SF Bronk GJ Gores 2002 Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent Am J Physiol Gastrointest Liver Physiol 283 G947 G956
52. WC Earnshaw LM Martins SH Kaufmann 1999 Mammalian caspases: structure, activation, substrates, and functions during apoptosis Annu Rev Biochem 68 383 424 10.1146/annurev.biochem.68.1.383
53. SM Srinivasula M Ahmad T Fernandes-Alnemri ES Alnemri 1998 Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization Mol Cell 1 949 957 10.1016/S1097-2765(00)80095-7
54. B Chaigne-Delalande JF Moreau P Legembre 2008 Rewinding the DISC Arch Immunol Ther Exp (Warsz) 56 9 14 10.1007/s00005-008-0002-9