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Volumn 292, Issue , 2008, Pages 130-136

Genetic and therapeutic control of diabetogenic CD8+ T cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD134 ANTIGEN; CD3 ANTIGEN; G6PC2 PROTEIN, MOUSE; GLUCOSE 6 PHOSPHATASE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 2; HISTOCOMPATIBILITY ANTIGEN; INTERLEUKIN 2; LIGAND; PEPTIDE; PROTEIN;

EID: 56249095153     PISSN: 15282511     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper
Times cited : (2)

References (35)
  • 1
    • 0028031644 scopus 로고
    • Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model
    • Aichele P, Kyburz D, Ohashi PS et al 1994 Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model. Proc Natl Acad Sci USA 91:444-448
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 444-448
    • Aichele, P.1    Kyburz, D.2    Ohashi, P.S.3
  • 2
    • 0034680105 scopus 로고    scopus 로고
    • Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
    • Amrani A, Verdaguer J, Serra P, Tafuro S, Tan R, Santamaria P 2000 Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature 406:739-742
    • (2000) Nature , vol.406 , pp. 739-742
    • Amrani, A.1    Verdaguer, J.2    Serra, P.3    Tafuro, S.4    Tan, R.5    Santamaria, P.6
  • 3
    • 0033529820 scopus 로고    scopus 로고
    • Prevalent CD8+ T cell response against one peptide/MHC complex in autoimmune diabetes
    • Anderson B, Park B, Verdaguer J, Amrani A, Santamaria P 1999 Prevalent CD8+ T cell response against one peptide/MHC complex in autoimmune diabetes. Proc Natl Acad Sci USA 96:9311-9316
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9311-9316
    • Anderson, B.1    Park, B.2    Verdaguer, J.3    Amrani, A.4    Santamaria, P.5
  • 4
    • 0021875480 scopus 로고
    • In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
    • Bottazzo GF, Dean BM, McNally JM, MacKay EH, Swift PG, Gamble DR 1985 In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis. N Engl J Med 313:353-360
    • (1985) N Engl J Med , vol.313 , pp. 353-360
    • Bottazzo, G.F.1    Dean, B.M.2    McNally, J.M.3    MacKay, E.H.4    Swift, P.G.5    Gamble, D.R.6
  • 5
    • 0032514701 scopus 로고    scopus 로고
    • MHC class I-restricted T-cells are required for all but end stages of diabetes development and utilize a prevalent T cell receptor a chain gene rearrangement
    • DiLorenzo TP, Graser RT, Ono T et al 1998 MHC class I-restricted T-cells are required for all but end stages of diabetes development and utilize a prevalent T cell receptor a chain gene rearrangement. Proc Natl Acad Sci USA 95:12538-12543
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12538-12543
    • DiLorenzo, T.P.1    Graser, R.T.2    Ono, T.3
  • 6
    • 0027957088 scopus 로고
    • A gene in the HLA class I region contributes to susceptibility to IDDM in the Finnish population. Childhood Diabetes in Finland (DiMe) Study Group
    • Fennessy M, Metcalfe K, Hitman GA et al 1994 A gene in the HLA class I region contributes to susceptibility to IDDM in the Finnish population. Childhood Diabetes in Finland (DiMe) Study Group. Diabetologia 37:937-945
    • (1994) Diabetologia , vol.37 , pp. 937-945
    • Fennessy, M.1    Metcalfe, K.2    Hitman, G.A.3
  • 7
    • 20944441042 scopus 로고    scopus 로고
    • Prevention of diabetes by manipulation of anti-IGRP autoimmunity: High efficiency of a low-affinity peptide
    • Han B, Serra P, Amrani A et al 2005a Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide. Nat Med 11:645-652
    • (2005) Nat Med , vol.11 , pp. 645-652
    • Han, B.1    Serra, P.2    Amrani, A.3
  • 8
    • 22144482328 scopus 로고    scopus 로고
    • Developmental control of CD8+ T cell-avidity maturation in autoimmune diabetes
    • Han B, Serra P, Yamanouchi J et al 2005b Developmental control of CD8+ T cell-avidity maturation in autoimmune diabetes. J Clin Invest 115:1879-1887
    • (2005) J Clin Invest , vol.115 , pp. 1879-1887
    • Han, B.1    Serra, P.2    Yamanouchi, J.3
  • 9
    • 18744385526 scopus 로고    scopus 로고
    • Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
    • Kent S, Chen Y, Bregoli L et al 2005 Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature 435:224-230
    • (2005) Nature , vol.435 , pp. 224-230
    • Kent, S.1    Chen, Y.2    Bregoli, L.3
  • 10
    • 0036333860 scopus 로고    scopus 로고
    • Autoreactive CD8+ T-cells in organ-specific autoimmunity: Emerging targets for therapeutic intervention
    • Liblau RS, Wong FS, Mars LT, Santamaria P 2002 Autoreactive CD8+ T-cells in organ-specific autoimmunity: emerging targets for therapeutic intervention. Immunity 17:1-6
    • (2002) Immunity , vol.17 , pp. 1-6
    • Liblau, R.S.1    Wong, F.S.2    Mars, L.T.3    Santamaria, P.4
  • 11
    • 0242364727 scopus 로고    scopus 로고
    • A comprehensive guide to antibody and T-cell responses in type 1 diabetes
    • Lieberman S, DiLorenzo T 2003 A comprehensive guide to antibody and T-cell responses in type 1 diabetes. Tissue Antigens 62:359-377
    • (2003) Tissue Antigens , vol.62 , pp. 359-377
    • Lieberman, S.1    DiLorenzo, T.2
  • 12
    • 0037478632 scopus 로고    scopus 로고
    • Identification of the b-cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes
    • Lieberman SM, Evans AM, Han B et al 2003 Identification of the b-cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci USA 100:8384-8388
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8384-8388
    • Lieberman, S.M.1    Evans, A.M.2    Han, B.3
  • 13
    • 27144512284 scopus 로고    scopus 로고
    • Genetic susceptibility to type 1 diabetes
    • Maier L, Wicker L 2005 Genetic susceptibility to type 1 diabetes. Curr Opin Immunol 17: 601-608
    • (2005) Curr Opin Immunol , vol.17 , pp. 601-608
    • Maier, L.1    Wicker, L.2
  • 14
    • 33847338541 scopus 로고    scopus 로고
    • CD8+ T-cell responses identify beta cell autoimmunity in human type 1 diabetes
    • Mallone R, Martinuzzi E, Blancou P et al 2007 CD8+ T-cell responses identify beta cell autoimmunity in human type 1 diabetes. Diabetes 56:613-621
    • (2007) Diabetes , vol.56 , pp. 613-621
    • Mallone, R.1    Martinuzzi, E.2    Blancou, P.3
  • 15
    • 33745289128 scopus 로고    scopus 로고
    • Modeling competition among autoreactive CD8+ T-cells in autoimmune diabetes: Implications for antigen-specific therapy
    • Maree A, Santamaria P, Edelstein-Keshet L 2006 Modeling competition among autoreactive CD8+ T-cells in autoimmune diabetes: implications for antigen-specific therapy. Int Immunol 18:1067-1077
    • (2006) Int Immunol , vol.18 , pp. 1067-1077
    • Maree, A.1    Santamaria, P.2    Edelstein-Keshet, L.3
  • 16
    • 0035816652 scopus 로고    scopus 로고
    • Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes
    • Martin CC, Bischof LJ, Bergman B et al 2001 Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes. J Biol Chem 276:25197-25207
    • (2001) J Biol Chem , vol.276 , pp. 25197-25207
    • Martin, C.C.1    Bischof, L.J.2    Bergman, B.3
  • 17
    • 18744366947 scopus 로고    scopus 로고
    • Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice
    • Nakayama M, Abiru N, Moriyama H et al 2005 Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature 435:220-223
    • (2005) Nature , vol.435 , pp. 220-223
    • Nakayama, M.1    Abiru, N.2    Moriyama, H.3
  • 18
    • 29444433680 scopus 로고    scopus 로고
    • Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes
    • Pinkse G, Tysma O, Bergen CA et al 2005 Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes. Proc Natl Acad Sci USA 102:18425-18430
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18425-18430
    • Pinkse, G.1    Tysma, O.2    Bergen, C.A.3
  • 19
    • 0026565852 scopus 로고
    • Characterization of T lymphocytes infiltrating human pancreas allograft affected by isletitis and recurrent of diabetes
    • Santamaria P, Nakhleh R, Sutherland DE, Barbosa JJ 1992 Characterization of T lymphocytes infiltrating human pancreas allograft affected by isletitis and recurrent of diabetes. Diabetes 41:53-61
    • (1992) Diabetes , vol.41 , pp. 53-61
    • Santamaria, P.1    Nakhleh, R.2    Sutherland, D.E.3    Barbosa, J.J.4
  • 20
    • 0028931879 scopus 로고
    • Beta cell cytotoxic CD8+ T cells from non-obese diabetic mice use highly homologous T cell receptor alpha chain CDR3 sequences
    • Santamaria P, Utsugi T, Park BJ, Averill N, Kawazu S, Yoon JW 1995 Beta cell cytotoxic CD8+ T cells from non-obese diabetic mice use highly homologous T cell receptor alpha chain CDR3 sequences. J Immunol 154:2494-2503
    • (1995) J Immunol , vol.154 , pp. 2494-2503
    • Santamaria, P.1    Utsugi, T.2    Park, B.J.3    Averill, N.4    Kawazu, S.5    Yoon, J.W.6
  • 21
    • 0347480215 scopus 로고    scopus 로고
    • CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells
    • Serra P, Amrani A, Yamanouchi J et al 2003 CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. Immunity 19:877-889
    • (2003) Immunity , vol.19 , pp. 877-889
    • Serra, P.1    Amrani, A.2    Yamanouchi, J.3
  • 22
    • 0021873134 scopus 로고
    • Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases
    • Sibley R, Sutherland D, Goetz F, Michael AF 1985 Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases. Lab Invest 53:132-144
    • (1985) Lab Invest , vol.53 , pp. 132-144
    • Sibley, R.1    Sutherland, D.2    Goetz, F.3    Michael, A.F.4
  • 23
    • 33845533220 scopus 로고    scopus 로고
    • Identification of novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
    • Standifer NE, Ouyang Q, Panagiotopoulos C et al 2006 Identification of novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives. Diabetes 55:3061-3067
    • (2006) Diabetes , vol.55 , pp. 3061-3067
    • Standifer, N.E.1    Ouyang, Q.2    Panagiotopoulos, C.3
  • 24
    • 33644501795 scopus 로고    scopus 로고
    • HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes
    • Takaki T, Marron M, Matthews CE et al 2006 HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. J Immunol 176:3257-3265
    • (2006) J Immunol , vol.176 , pp. 3257-3265
    • Takaki, T.1    Marron, M.2    Matthews, C.E.3
  • 25
    • 29244482759 scopus 로고    scopus 로고
    • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
    • Tang Q, Adams J, Tooley AJ et al 2006 Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 7:83-92
    • (2006) Nat Immunol , vol.7 , pp. 83-92
    • Tang, Q.1    Adams, J.2    Tooley, A.J.3
  • 26
    • 84969213492 scopus 로고    scopus 로고
    • The Wellcome Trust Case Control Consortium 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678
    • The Wellcome Trust Case Control Consortium 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678
  • 27
    • 34347341846 scopus 로고    scopus 로고
    • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
    • Todd JA, Walker NM, Cooper JD et al 2007 Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 39:857-895
    • (2007) Nat Genet , vol.39 , pp. 857-895
    • Todd, J.A.1    Walker, N.M.2    Cooper, J.D.3
  • 28
    • 0029798058 scopus 로고    scopus 로고
    • Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction
    • Toes R, Offringa R, Blom RJ, Melief CJ, Kast WM 1996 Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction. Proc Natl Acad Sci USA 93:7855-7860
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7855-7860
    • Toes, R.1    Offringa, R.2    Blom, R.J.3    Melief, C.J.4    Kast, W.M.5
  • 29
    • 23044455740 scopus 로고    scopus 로고
    • Recognition of a subregion of human proinsulin by class I- restricted T cells in type 1 diabetic patients
    • Toma A, Haddouk S, Briand JP et al 2005 Recognition of a subregion of human proinsulin by class I- restricted T cells in type 1 diabetic patients. Proc Natl Acad Sci USA 102:10581-10586
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10581-10586
    • Toma, A.1    Haddouk, S.2    Briand, J.P.3
  • 30
    • 0037237655 scopus 로고    scopus 로고
    • Autoreactive T cells in peripheral blood predict development of type 1 diabetes
    • Trudeau J, Kelly-Smith C, Verchere CB et al 2003 Autoreactive T cells in peripheral blood predict development of type 1 diabetes. J Clin Invest 111:217-223
    • (2003) J Clin Invest , vol.111 , pp. 217-223
    • Trudeau, J.1    Kelly-Smith, C.2    Verchere, C.B.3
  • 31
    • 34347324029 scopus 로고    scopus 로고
    • A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
    • van Heel DA, Franke L, Hunt KA et al 2007 A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet 39:827-829
    • (2007) Nat Genet , vol.39 , pp. 827-829
    • van Heel, D.A.1    Franke, L.2    Hunt, K.A.3
  • 32
    • 0030588572 scopus 로고    scopus 로고
    • Acceleration of spontaneous diabetes in TCRb-transgenic nonobese diabetic mice by beta cell-cytotoxic CD8+ T-cells expressing identical endogenous TCRa chains
    • Verdaguer J, Yoon JW, Anderson B et al 1996 Acceleration of spontaneous diabetes in TCRb-transgenic nonobese diabetic mice by beta cell-cytotoxic CD8+ T-cells expressing identical endogenous TCRa chains. J Immunol 157:4726-4735
    • (1996) J Immunol , vol.157 , pp. 4726-4735
    • Verdaguer, J.1    Yoon, J.W.2    Anderson, B.3
  • 34
    • 0032823399 scopus 로고    scopus 로고
    • Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
    • Wong F, Karttunen J, Dumont C et al 1999 Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library. Nat Med 5:1026-1031
    • (1999) Nat Med , vol.5 , pp. 1026-1031
    • Wong, F.1    Karttunen, J.2    Dumont, C.3
  • 35
    • 33847246293 scopus 로고    scopus 로고
    • Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
    • Yamanouchi J, Rainbow D, Serra P et al 2007 Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet 39:329-337
    • (2007) Nat Genet , vol.39 , pp. 329-337
    • Yamanouchi, J.1    Rainbow, D.2    Serra, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.