Ultrafine (nanometre) particle mediated lung injury

Journal of Aerosol Science

Volumn 29, Issue 5-6, 1998, Pages 553-560

  Donaldson, K ^a,b   Li, X Y ^a   MacNee, W ^a  

^a EDINBURGH NAPIER UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AIR POLLUTION; ATMOSPHERIC CHEMISTRY; CELLS; EPIDEMIOLOGY; FREE RADICALS; LIVING SYSTEMS STUDIES; NANOSTRUCTURED MATERIALS; PARTICLES (PARTICULATE MATTER); PULMONARY DISEASES;

MACROPHAGES; PHAGOCYTOSE;

ATMOSPHERIC AEROSOLS;

CARBON; FREE RADICAL; HYDROXYL RADICAL; TITANIUM DIOXIDE;

AIR POLLUTION; AIRBORNE PARTICLE; ARTICLE; DUST; DUST EXPOSURE; INTERSTITIUM; LUNG INJURY; MACROPHAGE; MORBIDITY; MORTALITY; OXIDATIVE STRESS; PARTICLE SIZE; PHAGOCYTOSIS; PRIORITY JOURNAL;

EID: 0032101141     PISSN: 00218502     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-8502(97)00464-3     Document Type: Article

References (37)

1. Allison, A. C., Harington, J. S. and Birbeck, M. (1966) An examination of the cytotoxic effects of silica on macrophages. J. Exp. Med. 124, 141-153.
2. Bauerle, P. A. and Henkel, T. (1994) Function and activation of NF kappa B in the immune system. Ann. Rev. Immunol. 12, 141-179.
3. Castranova, V., Dalal, N. S. and Vallyathan, V. (1996) Role of surface free radicals in the pathogenicity of silica. In Silica and Ciilca-induced Diseases. (Edited by Castranova, V., Vallyathan, V. and Wallace, W. E.) CRC Press, Boca Raton.
4. Dalal, N. S., Suryan, M. M., Vallyathan, V., Green, F. H. Y., Jafari, B. and Wheeler, R. (1989) Detection of reactive free radicals in fresh coalmine dust and their implication for pulmonary injury. Ann. Occup. Hyg. 33, 79-84.
5. Davis, J. M. G., Bolton, R. E., Donaldson, K., Jones, A. D. and Smith, T. (1985) The pathogenicity of long versus short fibres of amosite asbestos administered to rats by inhalation and intraperitoneal injection. Br. J. Exp. Pathol. 67, 415-430.
6. Donaldson, K., Brown, G. M., Brown, D. M., Bolton, R. E.and Davis, J. M. G. (1989) The inflammation generating potential of long and short fibre amosite asbestos samples. Br. J. Ind. Med. 46, 271-276.
7. Dreher, K. L., Jaskot, R. H., Lehmann, J. R., Richards, J. H., McGee, J. K. and Ohio, A. J. (1997) Soluble transition metals mediate residual oil fly ash induced lung injury. J. Toxicol. Environ. Health 50, 286-305.
8. Driscoll, K. E., Higgins, J. M., Leytart, M. J. and Crosby, L. L. (1990) Differential effects of mineral dusts on the in vitro activation of alveolar macrophage eicosanoid and cytokine release. Toxic, in Vitro 4, 284-288.
9. Driscoll, K.E. (1996) Role of inflammation in the development of rat lung tumours in response to chronic particle exposure. Inhalation Tax. 8, (Suppl), 139-153.
10. Driscoll, K. E., Carter, J. M., Howard, B. W., Hassenbein, D. G., Pepelko, W., Baggs, R. B. and Oberdorster, G. (1996) Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon-black. Toxicol. Appl. Pharmacol. 136, 372-380.
11. Driscoll, K. E., Deyo, L. C., Howard, B. W., Poynter, J. and Carter, J. M. (1995) Characterizing mutagenesis in the hprt gene of rat alveolar epithelial-cells. Exp. Lung Res. 21, 941-956.
12. Ferin, J., Oberdorster, G., Penney, D. P., Soderholm, S. C., Gelein, R. and Piper, H. C. (1990) Increased pulmonary toxicity of ultrafine particles? 1 Particle clearance, translocation, morphology. J. Aerosol Sei. 21, 384-387.
13. Ferin, J., Oberdorster, G. and Penney, D. P. (1992) Pulmonary retention of ultrafine and fine particles in rats. Am. J. Respir. Cell Mol. Biol. 6, 535-542.
14. Fubini, B., Bolis, V., Cavenago, A. and Volante, M. ( 1995) Physicochemical properties of crystalline silica dusts and their possible implication in various biological responses. Scand. J. Environ. Health 21 (Suppl. 2) 9-14.
15. Fubini, B. (1993) The possible role of surface chemistry in the toxicity of inhaled fibres. In Fiber Toxicology (Edited by D. Warheit), pp. 229-257. Academic Press, New York.
16. 10: involvement of iron in the generation of hydroxyl radical. Occup. Environ. Med. 53, 817-822.
17. Gilmour, P. S., Brown, D., Beswick, P. H., Benton, E., MacNee, W. and Donaldson, K. (1997) Surface free radical activity of PM10 and ultrafine titanium dioxide: a unifying factor in their toxicity? Ann Occup. Hyg. 41 (Suppl. 1), 32-38.
18. Heinrich, U., Fuhst, R., Rittinghausen, O., Creutzenberg, B., Koch, W. and Levsen, K. (1995) Chronic inhalation exposure of Wistar rts and two different strains of mice to diesel exhaust, carbon black and titnium dioxide. Inhalation Toxicol. 7, 533-556.
19. Janssen, J. M. W., Marsh, J. P., Driscoll, K. E., Borm, P. J. A. and Oberdorster, G. (1994) Increased expression of manganese-containing superoxide dismutase in rat lungs after inhalation of inflammatory and fibrogenic minerals. Free Radical Bio. Med. 16, 315-322.
20. Johnston, C. J., Finkelstein, J. N., Gelein, R., Baggs, R. and Oberdorster, G. (1996) Characterisation of the early pulmonary inflammatory response associated with PTFE fume exposure. Toxicol. Appl. Pharmacol. 140, 154-163.
21. Kamp, D. W., Gracefa, P., Pryor, W. A. and Weitzman, S. A. (1992) The role of free radicals in asbestos-induced diseases. Free Radical Biol. 12, 293-315.
22. 10) in vivo and in vitro. Thorax. 51, 1216-1222.
23. 10) in vivo and in vitro. Ann Occup. Hyg. 41 (Suppl. 1), 7-13.
24. Mauderly, J. L. and McCunney, R. J. (1996) Particle overload in the rat lung and lung cancer: Implications for human risk assessment. Proc. Conf. held in the Massachusetts Institute of Technology. March 1995. Inhalation Toxicol. 8 (Suppl.).
25. Mauderly, J. L. (1996) Lung overload: the dilemma and opportunities for resolution. Inhalation Toxicol. 8 (Suppl.) 1-28.
26. Meyer, M., Pahl, H. K. and Bauerle, P. A. (1994) Regulation of the transcription factors NF-kB and AP-1 by redox changes. Chem. Biol. Interact. 91, 91-100.
27. Morrow, P. E. (1988) Possible mechanisms to explain dust overloading of the lungs. Fundam. Appl. Toxicol. 10, 369-384.
28. Oberdorster, G. Ferin, J. and Morrow, P. E. (1992) Volumetric loading of alveolar macrophages (AM): a possible basis for diminished AM-mediated particle clearance. Exp. Lung Res. 18, 87-104.
29. Oberdorster, G., Ferin, J. and Lehnert, B. E. (1994) Correlation between particle size, in vivo particle persistence and lung injury. Environ. Health Perspect. 102 (Suppl. 5), 173-179.
30. Oberdorster, G., Gelein, R., Ferin, J. and Weiss, B. (1995) Association of particulate air pollution and acute mortality: involvement of ultrafine particles. Inhalation Toxicol. 71, 111-124.
31. Oberdorster, G. (1996) Significance of particle parameters in the evaluation of exposure-dose relationships of inhaled particles. Inhalation Toxicol. 8 (Suppl.), 73-90.
32. Rahman, I., Morrison, D., Donaldson, K. and MacNee, W. (1996) Systemic oxidative stress in asthma, COPD and smokers. Am. J. Resp. Crit. Care Med. 154, 1055-1060.
33. Seaton, A., MacNee, W., Donaldson, K. and Godden, D. (1995) Particulate air pollution and acute health effects. The Lancet. 345, 176-178.
34. Shi, M. M., Godleski, J. J. and Paulauskis, J. D. (1996) Regulation of macrophage inflammatory protein-1-alpha messenger-RNA by oxidative stress. J. Biol. Chem. 271, 5878-5883.
35. Simeonova, P. P. and Luster, M. I. (1995) Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-alpha response from alveolar macrophages. Am. J. Resp. Cell Mol. Biol. 12, 676-683.
36. Vallyathan, V., Shi, X., Dalai, N. S., Irr, W. and Castranova, V. (1988) Generation of free radicals from freshly fractured silica dust: potential role in acute silica-induced lung injury. Am. Rev. Resp. Dis. 138, 1213-1219.
37. Zhang, Q., Kusaka, Y., Sato, K., Nakakuki, K. and Donaldson, K. Differences in the inflammogenicity of 3 ultrafine metals: evidence for the role of surface free radical activity. Toxicol. Environ. Health (in press).