Interactions between cytochromes P450, glutathione S-transferases and Ghanaian medicinal plants

Food and Chemical Toxicology

Volumn 46, Issue 12, 2008, Pages 3598-3603

  Appiah Opong, Regina ^a   Commandeur, Jan N M ^a   Axson, Civianny ^a   Vermeulen, Nico P E ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cytochromes P450; Enzyme inhibition; Glutathione S transferases; Herb drug interactions

Indexed keywords

CASSIA SIAMEA EXTRACT; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; LACTUCA TARAXICIFOLIA EXTRACT; MOMORDICA CHARANTIA EXTRACT; MORINDA LUCIDA EXTRACT; PHYLLANTHUS AMARUS EXTRACT; PLANT EXTRACT; RECOMBINANT ENZYME; TRIDAX PROCUMBENS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CASSIA SIAMEA; CYTOSOL; ENZYME INHIBITION; GHANA; HERB DRUG INTERACTION; IC 50; LACTUCA TARAXICIFOLIA; MEDICINAL PLANT; MOMORDICA CHARANTIA; MORINDA LUCIDA; NONHUMAN; PHYLLANTHUS AMARUS; PLANT LEAF; PLANT ROOT; PLANT STEM; PROTEIN EXPRESSION; RAT; TRIDAX PROCUMBENS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTITUSSIVE AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; DICLOFENAC; ENZYME INHIBITORS; GHANA; GLUTATHIONE TRANSFERASE; HYDROXYLATION; INDICATORS AND REAGENTS; MEMBRANES; PLANT EXTRACTS; PLANTS, MEDICINAL; PLASMIDS; RATS;

ESCHERICHIA COLI; MOMORDICA CHARANTIA; PHYLLANTHUS AMARUS; RATTUS; SENNA ALATA; SENNA SIAMEA;

EID: 55949096758     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.09.002     Document Type: Article

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