Inhibition of drug metabolizing enzymes (cytochrome P450) in vitro as well as in vivo by Phyllanthus amarus Schum & Thonn

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 7, 2006, Pages 1310-1313

  Hari Kumar, Kuzhuvelil Bhaskarannair ^a   Kuttan, Ramadasan ^a  

^a AMALA CANCER RESEARCH CENTRE   (India)

Author keywords

Cytochrome P450; Phenobarbitone; Phyllanthus amarus; Xenobiotic

Indexed keywords

7 METHOXYRESORUFIN O DEMETHYLASE; AMINOPYRINE N DEMETHYLASE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2A; CYTOCHROME P450 2B; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2D; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; ETHOXYRESORUFIN DEETHYLASE; ISOENZYME; PENTOXYRESORUFIN DEALKYLASE; PHENOBARBITAL; PHYLLANTHUS AMARUS EXTRACT; RESORUFIN DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARCINOGENESIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INHIBITION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME METABOLISM; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROSOME; NONHUMAN; RAT;

AMINOPYRINE N-DEMETHYLASE; ANILINE HYDROXYLASE; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; ISOENZYMES; KINETICS; MALE; MICROSOMES, LIVER; PHYLLANTHUS; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 33745714104     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.1310     Document Type: Article

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