LYVE-1, the lymphatic system and tumor lymphangiogenesis

Trends in Immunology

Volumn 22, Issue 6, 2001, Pages 317-321

  Jackson, David G ^a   Prevo, Remko ^a   Clasper, Steven ^a   Banerji, Suneale ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; HERMES ANTIGEN; HYALURONIC ACID; LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR; MEMBRANE RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL MIGRATION; GLYCOSYLATION; HISTOPATHOLOGY; HUMAN; INFLAMMATORY CELL; LEUKOCYTE; LYMPH NODE; LYMPH VESSEL; LYMPHATIC SYSTEM; MOLECULAR BIOLOGY; REVIEW; TUMOR CELL;

ANIMALS; ANTIGENS, CD44; BIOLOGICAL MARKERS; GLYCOPROTEINS; HUMANS; LYMPHATIC SYSTEM; LYMPHATIC VESSEL TUMORS; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN CONFORMATION;

EID: 0034913816     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4906(01)01936-6     Document Type: Review

References (37)

1. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan
2. Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium
3. Hyaluronan: A multifunctional, megaDalton, stealth molecule
4. Hyaluronan-binding proteins in development, tissue homeostasis and disease
5. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis
6. Administration of antibodies to hyaluronan receptor (CD44) delays the start and ameliorates the severity of collagen II arthritis
7. CD44 is necessary for optimal contact allergic responses but is not required for normal leucocyte extravasation
8. Requirement for CD44 in activated T cell extravasation into an inflammatory site
9. CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma
10. Hyaluronan
11. Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages
12. Hyaluronan fragments activate an NF-κB/I-κB α autoregulatory loop in murine macrophages
13. Angiogenesis induced by degradation products of hyaluronic acid
14. Uptake and degradation of hyaluronan in lymphatic tissue
15. Turnover and metabolism of hyaluronan
16. Solution structure of the link module: A hyaluronan binding domain involved in extracellular matrix stability and cell migration
17. The protein fold of the hyaluronate-binding proteoglycan tandem repeat domain of link protein, aggrecan and CD44 is similar to that of the C-type lectin superfamily
18. CD44 in inflammation and metastasis
19. CD44 is the principal cell surface receptor for hyaluronate
20. CD44 and its interaction with the extracellular matrix
21. Molecular organization, structural features and ligand binding characteristics of CD44, a highly variable cell surface glycoprotein with multiple functions
22. Identification of hyaluronic acid binding sites in the extracellular domain of CD44
23. Identification of CD44 residues important for hyaluronan binding and delineation of the binding site
24. Characterization of a functional hyaluronan-binding domain from the human CD44 molecule expressed in Escherichia coli
25. Phorbol myristate acetate stimulates the dimerization of CD44 involving a cysteine in the transmembrane domain
26. The importance of cellular environment to function of the CD44 matrix receptor
27. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: Podoplanin as a specific marker for lymphatic endothelium
28. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
29. Inhibition of hyaluronan uptake in lymphatic tissue by chondroitin sulphate proteoglycan
30. Lymphangiogenesis and tumor metastasis: Myth or reality?
31. VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
32. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
33. Lack of lymphatics specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumours
34. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
35. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
36. Induction of tumor lymphangiogenesis by vascular endothelial growth factor-C promotes breast cancer metastasis
37. Vascular endothelial growth factor-D promotes tumour growth and spread via the lymphatics