Amino acids involved in conformational dynamics and G protein coupling of an odorant receptor: Targeting gain-of-function mutation

Journal of Neurochemistry

Volumn 107, Issue 5, 2008, Pages 1261-1270

  Kato, Aya ^a   Katada, Sayako ^a   Touhara, Kazushige ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Guanine nucleotide binding protein; Mutagenesis; Odorant receptor; Signal transduction

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; ODORANT RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG TARGETING; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY SYSTEM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SENSORY NERVE CELL; SENSORY STIMULATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

AMINO ACIDS; CALCIUM; CELL LINE; CYCLIC AMP; FLOW CYTOMETRY; GTP-BINDING PROTEINS; HUMANS; IMMUNOPRECIPITATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; NONLINEAR DYNAMICS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ODORANT; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 55849127127     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05693.x     Document Type: Article

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