Burst analysis spectroscopy: A versatile single-particle approach for studying distributions of protein aggregates and fluorescent assemblies

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 38, 2008, Pages 14400-14405

  Puchalla, Jason ^a   Krantz, Kelly ^a   Austin, Robert ^a   Rye, Hays ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Aggregation; Fluorescence spectroscopy; Microfluidics.

Indexed keywords

CARBOXYLASE; CHAPERONIN; OXYGENASE; RIBULOSEBISPHOSPHATE CARBOXYLASE;

ARTICLE; CONFOCAL MICROSCOPY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FOLDING; SIGNAL NOISE RATIO; SPECTROSCOPY;

FLUORESCENCE; KINETICS; MULTIPROTEIN COMPLEXES; PEPTIDE TERMINATION FACTORS; PRIONS; PROTEIN BINDING; RHODOSPIRILLUM RUBRUM; RIBULOSE-BISPHOSPHATE CARBOXYLASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS;

EID: 55749100687     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0805969105     Document Type: Article

References (30)

1. Chiti F, Dobson CM (2006) Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 75:333-366.
2. Caughey B, Lansbury PT (1996) Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci 26:267-298.
3. Philo JS (2006) Is any measurement method optimal for all aggregate sizes and types? AAPS J 8:E564-E571.
4. Cromwell MEM, Hilario E, Jacobson F (2006) Protein aggregation and bioprocessing. AAPS J 8:E572-E579.
5. Bieschke J, et al. (2000) Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets. Proc Natl Acad Sci USA 97:5468-5473.
6. Ban T, Goto Y (2006) Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy. Methods Enzymol 413:91-102.
7. Giese A, et al. (2005) Single particle detection and characterization of synuclein coaggregation. Biochem Biophys Res Commun 333:1202-1210.
8. Chen Y, Wei LN, Muller JD (2003) Probing protein oligomerization in living cells with fluorescence fluctuation spectroscopy. Proc Natl Acad Sci USA 100:15492-15497.
9. Muller JD, Chen Y, Gratton E (2000) Resolving heterogeneity on the single molecular level with the photon-counting histogram. Biophys J 78:474-486.
10. Kask P, Palo K, Ullmann D, Gall K (1999) Fluorescence-intensity distribution analysis and its application in biomolecular detection technology. Proc Natl Acad Sci USA 96:13756-13761.
11. Chen Y, Muller JD, So PT, Gratton E (1999) The photon counting histogram in fluorescence fluctuation spectroscopy. Biophys J 77:553-567.
12. Eggeling C, et al. (2001) Data registration and selective single-molecule analysis using multi-parameter fluorescence detection. J Biotechnol 86:163-180.
13. Kuhnemuth R, Seidel CAM (2001) Principles of single molecule multiparameter fluorescence spectroscopy. Single Molecules 2:251-254.
14. Schwille P, Meyer-Almes FJ, Rigler R (1997) Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution. Biophys J 72:1878-1886.
15. Bacia K, Kim SA, Schwille P (2006) Fluorescence cross-correlation spectroscopy in living cells. Nat Methods 3:83-89.
16. Meyer T, Schindler H (1988) Particle counting by fluorescence correlation spectroscopy - simultaneous measurement of aggregation and diffusion of molecules in solutions and in membranes. Biophys J 54:983-993.
17. Berland KM, So PTC, Chen Y, Mantulin WW, Gratton E (1996) Scanning two-photon fluctuation correlation spectroscopy: Particle counting measurements for detection of molecular aggregation. Biophys J 71:410-420.
18. Qian H, Elson EL (1991) Analysis of confocal laser-microscope optics for 3-D fluorescence correlation spectroscopy. Applied Optics 30:1185-1195.
19. Hess ST, Webb WW (2002) Focal volume optics and experimental artifacts in confocal fluorescence correlation spectroscopy. Biophys J 83:2300-2317.
20. Meakin P (1992) Aggregation kinetics. Phys Scr 46:295-331.
21. Goloubinoff P, Christeller JT, Gatenby AA, Lorimer GH (1989) Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP. Nature 342:884-889.
22. Lin Z, Rye HS (2004) Expansion and compression of a protein folding intermediate by GroEL. Mol Cell 16:23-34.
23. Collins SR, Douglass A, Vale RD, Weissman JS (2004) Mechanism of prion propagation: Amyloid growth occurs by monomer addition. PLoS Biol 2:e321.
24. Shorter J, Lindquist S (2004) Hsp 104 catalyzes formation and elimination of self-replicating Sup35 prion conformers. Science 304:1793-1797.
25. Patino MM, Liu JJ, Glover JR, Lindquist S (1996) Support for the prion hypothesis for inheritance of a phenotypic trait in yeast. Science 273:622-626.
26. Naiki H, Higuchi K, Hosokawa M, Takeda T (1989) Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1. Anal Biochem 177:244-249.
27. Stray SJ, Johnson JM, Kopek BG, Zlotnick A (2006) An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly. Nat Biotechnol 24:358-362.
28. Hagan MF, Chandler D (2006) Dynamic pathways for viral capsid assembly. Biophys J 91:42-54.
29. Pallitto MM, Murphy RM (2001) A mathematical model of the kinetics of beta-amyloid fibril growth from the denatured state. Biophys J 81:1805-1822.
30. Enderlein J, Robbins DL, Ambrose WP, Keller RA (1998) Molecular shot noise, burst size distribution, and single-molecule detection in fluid flow: Effects of multiple occupancy. J Phys Chem A 102:6089-6094.