Data registration and selective single-molecule analysis using multi-parameter fluorescence detection

Journal of Biotechnology

Volumn 86, Issue 3, 2001, Pages 163-180

  Eggeling, C ^a   Berger, S ^a   Brand, L ^a   Fries, J R ^a   Schaffer, J ^a   Volkmer, A ^a   Seidel, C A M ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Fluorescence anisotropy; Fluorescence correlation spectroscopy; Fluorescence lifetime; Green fluorescent protein; High through put screening; Single molecule

Indexed keywords

GREEN FLUORESCENT PROTEIN; OLIGONUCLEOTIDE;

ANISOTROPY; ARTICLE; CONFOCAL MICROSCOPY; CONFORMATION; DIFFUSION; FLUORESCENCE; INFORMATION PROCESSING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SPECTROSCOPY;

FLUORESCENT DYES; GREEN FLUORESCENT PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; LUMINESCENT PROTEINS; MODELS, CHEMICAL; OLIGONUCLEOTIDES; RHODAMINE 123; SPECTROMETRY, FLUORESCENCE; TIME FACTORS;

EID: 0035853637     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(00)00412-0     Document Type: Article

References (43)

1. Application of single molecule detection to DNA sequencing and sizing
2. Single-molecule identification of coumarin-120 by time-resolved fluorescence detection - Comparison of one- and two-photon excitation in solution
3. Single-molecule detection in capillary electrophoresis: Molecular shot noise as a fundamental limit to chemical analysis
4. The photon counting histogram in fluorescence fluctuation spectroscopy
5. Techniques for single molecule sequencing
6. Conformational transitions monitored for single molecules in solution
7. Heterogeneity in single DNA conformational fluctuations
8. Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy
9. Rotational Brownian motion and fluorescence intensity fluctuations
10. Sorting single molecules: Application to diagnostics and evolutionary biotechnology
11. Fluorescence correlation spectroscopy. I. Conceptual basis and theory
12. A maximum likelihood estimator to distinguish single molecules by their fluorescence decays
13. The statistics of single molecule detection: An overview
14. Comparison between time-correlated single photon counting and fluorescence correlation spectroscopy in single molecule identification
15. Molecular shot noise, burst size distribution, and single molecule detection in fluid flow: Effects of multiple occupancy
16. Quantitative identification of different single-molecules by selective time-resolved confocal fluorescence spectroscopy
17. Fluorescence-intensity distribution analysis and its application in biomolecular detection technology
18. Single-molecule fluorescence analysis in solution
19. Determination of the diffusion coefficient of dye in solution at single molecule level
20. Statistical accuracy in fluorescence correlation spectroscopy
21. Time-dependent fluorescence depolarization analysis in three dimensional microscopy
22. Thermodynamic fluctuations in a reacting system - Measurement by fluorescence correlation spectroscopy
23. Submillisecond detection of single rhodamine molecules in water
24. Time-resolved identification of single molecules in solution with a pulsed semiconductor diode laser
25. Probing individual molecules with confocal fluorescence microscopy
26. Crystal structure of the Aequorea victoria green fluorescent protein
27. Fluorescence correlations, single molecule detection and large number screening - Applications in biotechnology
28. Ultrasensitive detection of single molecules by fluorescence correlation spectroscopy
29. Time-resolved identification of individual mononucleotide molecules in aqueous solution with pulsed semiconductor lasers
30. Dynamics of the electron transfer reaction between an oxazine dye and DNA oligonucleotides monitored on the single-molecule level
31. Identification of single molecules in aqueous solution by time-resolved fluorescence spectroscopy
32. Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution
33. Nucleobase-specific quenching of fluorescent dyes. 1. Nucleobase one-electron redox potentials and their correlation with static and dynamic quenching efficiencies
34. Detection of single fluorescent molecules
35. Detection and identification of single molecules in solution
36. Analysis of fluorescence lifetime data for single rhodamine molecules in flowing sample streams
37. Fluorescence correlation spectroscopy
38. Conformational fluctuations in single DNA molecules
39. Fluorescence correlation spectroscopy of triplet states in solution: A theoretical and experimental study
40. Detection and characterization of single molecules in aqueous solution